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Single dose of BNT162b2 vaccine after COVID provides 82% reduction in reinfection risk

Researchers compare the incidence rate of reinfection in convalescent and unvaccinated people to that in recovered and single-dose vaccinated people.

16 Feb 2022

Omicron breakthrough boosts neutralization titers a little more than a 3rd COVID vaccine dose

Researchers compare the neutralizing antibody titers in individuals who received two or three mRNA vaccine doses and experienced breakthrough infections.

16 Feb 2022

Study analyzes trends in overdose deaths from use of non-benzodiazepines and gabapentinoids

With an alarming rise in the number of prescriptions filled for non-benzo sleeping/z-drugs and anti-epilepsy gabapentinoids over the last two decades, researchers at Columbia University Mailman School of Public Health aimed to fill in the gap in knowledge in the proportion of overdose deaths involving those medications and learn more about their co-usage with other substances across U.S. demographics categories.

16 Feb 2022

Study shows the true prevalence of statin intolerance worldwide is between 6 to 10%

As many as one in two patients stop taking statins, reduce the dose or take them irregularly because they believe the cholesterol-lowering drugs cause muscle pain and other side-effects.

16 Feb 2022

Inside the tactical tug of war over the controversial Alzheimer’s drug

The drug industry, patient advocates, and congressional Republicans have all attacked federal officials' decision to decline routine Medicare coverage for a controversial Alzheimer's drug.

16 Feb 2022

Two doses of psilocybin may ease depression symptoms for up to 12 months

Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month.

15 Feb 2022

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

Researchers select and study an RDV-resistant virus by serial passaging of wild type SARS-CoV-2 in the presence of increasing concentrations of RDV.

15 Feb 2022

Real-world data on efficacy and safety of COVID vaccines in Canada

In a recent study posted to the medRxiv* preprint server, researchers evaluated the efficacy and safety of the coronavirus disease 2019 (COVID-19) vaccines in young and elderly cohorts from Canada.

14 Feb 2022

Study finds Pfizer-BioNTech COVID vaccine doesn't increase pregnancy risk

A new JAMA Network study describes the effects of maternal COVID-19 vaccination on pregnancy outcomes and infant health.

14 Feb 2022

Researchers identify a powerful combination of antivirals to treat COVID-19

Researchers at the University of Maryland School of Medicine and University of Pennsylvania Perelman School of Medicine have identified a powerful combination of antivirals to treat COVID-19.

14 Feb 2022

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

In a study posted to the bioRxiv* preprint server, a team of researchers from the United States evaluated the protective effect of the preclinical version of the current Moderna Omicron-targeted mRNA-1273.529 vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 Omicron infection in mice.

14 Feb 2022

Assessing potential allergic reactions in COVID-19 vaccinated patients

Researchers analyze suspected reactions in patients vaccinated with the first and/or second dose of SARS-CoV-2 vaccines.

13 Feb 2022

Challenges in safely deprescribing common anticholinergic drugs

Medications with anticholinergic properties have been consistently associated with a wide range of adverse outcomes for older adults including cognitive impairment, yet these drugs continue to be commonly prescribed for depression, urinary incontinence, irritable bowel syndrome and Parkinson's disease.

11 Feb 2022

Direct oral anti-coagulants less likely to result in major bleeding after rare, fatal stroke

Direct oral anti-coagulant (anti-clotting) (DOAC) medications that target a single clotting factor work just as well to prevent future clots as the older, less-specific medication warfarin.

11 Feb 2022

Newer clot-busting drug may lengthen the window for additional stroke treatment to 24 hours

If patients with clot-caused strokes obtain medical care more than 4½ hours after their symptoms are noticed, it is too late to receive the standard clot-busting medication alteplase.

11 Feb 2022

Study tests efficacy of molnupiravir against SARS-CoV-2 VOCs in various animal models

A study published on the bioRxiv* preprint server evaluates molnupiravir against a panel of relevant VOCs using three efficacy models: primary human airway epithelium organoids, a ferret model of upper respiratory disease, and a Roborovski dwarf hamster model for severe COVID-19.

9 Feb 2022

Researchers identify a potent new combination of antiviral drugs to combat SARS-CoV-2

The recent success of Paxlovid has encouraged researchers to develop new anti-covid drugs. With this in mind, scientists from the University of Pennsylvania have been investigating a new synergistic treatment. Their research is released early as an unedited version of the manuscript to be published in the journal Nature.

9 Feb 2022

UCI case report: Antihistamines may provide relief for people suffering from long COVID-19 symptoms

Antihistamines may provide relief for the millions of people suffering from the painful, debilitating symptoms of long COVID-19 that impair daily functioning.

9 Feb 2022

Study highlights benefit of mRNA boosters for SARS-CoV-2 following different initial vaccine types

A study by researchers from the United Kingdom finds no difference in the protection offered by mRNA vaccine boosters against the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) when comparing those that have received BioNTech/Pfizer vaccine as a primary course to those that have received Oxford/AstraZeneca.

8 Feb 2022

SARS-CoV-2 Delta variant's effect on COVID-19 vaccine efficacy

In a recent research paper published in the journal Infection, the scientists estimated the transmission and disease severity associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant and the effectiveness of the current coronavirus disease 2019 (COVID-19) vaccines against the same by conducting a literature review. Further, a meta-analysis was conducted to obtain a numeric estimate of the vaccine effectiveness against the Delta variant.

7 Feb 2022

Pharmaceutical News

Single dose of BNT162b2 vaccine after COVID provides 82% reduction in reinfection risk

Omicron breakthrough boosts neutralization titers a little more than a 3rd COVID vaccine dose

Study analyzes trends in overdose deaths from use of non-benzodiazepines and gabapentinoids

Study shows the true prevalence of statin intolerance worldwide is between 6 to 10%

Inside the tactical tug of war over the controversial Alzheimer’s drug

Two doses of psilocybin may ease depression symptoms for up to 12 months

The in vitro selection of a remdesivir-resistant SARS-CoV-2 mutation

Real-world data on efficacy and safety of COVID vaccines in Canada

Study finds Pfizer-BioNTech COVID vaccine doesn't increase pregnancy risk

Researchers identify a powerful combination of antivirals to treat COVID-19

mRNA-1273 and mRNA-1273.529 Omicron-specific boosters highly effective in mouse model

Assessing potential allergic reactions in COVID-19 vaccinated patients

Challenges in safely deprescribing common anticholinergic drugs

Direct oral anti-coagulants less likely to result in major bleeding after rare, fatal stroke

Newer clot-busting drug may lengthen the window for additional stroke treatment to 24 hours

Study tests efficacy of molnupiravir against SARS-CoV-2 VOCs in various animal models

Researchers identify a potent new combination of antiviral drugs to combat SARS-CoV-2

UCI case report: Antihistamines may provide relief for people suffering from long COVID-19 symptoms

Study highlights benefit of mRNA boosters for SARS-CoV-2 following different initial vaccine types

SARS-CoV-2 Delta variant's effect on COVID-19 vaccine efficacy

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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Digital pathology and the PathoVerse: A conversation with Dr. Singh

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