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As overdose deaths soar, DEA-wary pharmacies shy from dispensing addiction medication

When Martin Njoku saw opioid addiction devastate his West Virginia community, he felt compelled to help. This was the place he'd called home for three decades, where he'd raised his two girls and turned his dream of owning a pharmacy into reality.

9 Nov 2021

Pfizer-BioNTech COVID-19 vaccine is associated with lower viral load in breakthrough infections

Several vaccines have been rapidly developed to help control the COVID-19 pandemic, including the BNT162b2 vaccine (Pfizer/BioNTech). This severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine has been shown in both clinical trials and in the real world to be highly efficacious in preventing infection, symptoms, hospitalizations, severe disease, and death related to coronavirus disease (COVID-19).

9 Nov 2021

Hemin as a potential therapy for COVID-19

The current study explores the antiviral activity of HO-1 induced by hemin against SARS-CoV-2 and attempts to describe the mechanism of its anti-viral action.

8 Nov 2021

Study compares efficacy of BNT162b2 and CoronaVac as the booster dose for COVID-19 vaccination

A recent study reports the immunogenicity and safety of BNT162b2 and CoronaVac as the third dose in CoronaVac-immunized adults.

8 Nov 2021

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

A new study describes a new small molecule compound that has shown impressive safety, tolerability, and bioavailability against SARS-CoV-2.

7 Nov 2021

Middlemen take home almost 53% of the net proceeds from insulin sales, finds study

Despite its discovery nearly 100 years ago, insulin's list price has been going up, not down, with trade secrets and other protections preventing researchers from pinpointing who is receiving profits from its sale.

7 Nov 2021

Therapeutics that target ceramides may help treat cardiometabolic disease

Therapeutics that target lipids called ceramides might hold potential for treating cardiometabolic disease, argues a review article published November 5th in the journal Trends in Pharmacological Sciences.

7 Nov 2021

Despite restraints, democrats’ drug pricing plan could still aid consumers

The Medicare prescription drug pricing plan Democrats unveiled this week is not nearly as ambitious as many lawmakers sought, but they and drug policy experts say the provisions crack open the door to reforms that could have dramatic effects.

5 Nov 2021

MHRA approves first oral antiviral for the treatment of COVID-19

The antiviral Lagevrio (molnupiravir) is safe and effective at reducing the risk of hospitalization and death in people with mild to moderate COVID-19 who are at increased risk of developing severe disease, the Medicines and Healthcare products Regulatory Agency announced today.

4 Nov 2021

Pfizer COVID-19 vaccine elicits durable specific memory T-cell response

A new preprint describes the protective efficacy of memory T-cells developed in response to the viral antigen, which could offer long-term immunity.

4 Nov 2021

Cuba reports 92.4 percent efficacy for 3 dose SOBERANA 02 COVID-19 vaccine

A new study describes the results of the safety and efficacy phase trials of a new COVID-19 vaccine from Cuba.

4 Nov 2021

Prior SARS-CoV-2 infection and risk of breakthrough infection following mRNA vaccination

The study, recently published in The Journal of the American Medical Association, deduced that previous SARS-CoV-2 infection is associated with a statistically significant reduced hazard of breakthrough infection among recipients of both the BNT162b2 (Pfizer-BioNTech) and the mRNA-1273 (Moderna) vaccines.

3 Nov 2021

Pre-clinical follow-up study boosting with original formulation and next generation INO-4802 SARS-CoV-2 vaccine candidate

Researchers describe the antibody-inducing effects of DNA-based synthetic vaccines INO-4800 and INO-4802 against SARS-CoV-2 in non-human primates.

3 Nov 2021

Waters and Sartorius partner to help bioprocess scientists accelerate clone selection and process development

Waters Corporation and Sartorius announced today they will partner to provide bioprocess experts with direct access to high-quality mass spectrometry (MS) data to accelerate the speed and improve the accuracy of biopharmaceutical process development.

From Sartorius 3 Nov 2021

Early combination treatment achieves clinically inactive disease in children with polyarticular JIA

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that patients started on early, aggressive treatment with a combination of biologic and conventional disease modifying antirheumatic drugs (DMARDs) achieved clinically inactive disease in children with polyarticular juvenile idiopathic arthritis (JIA) more frequently compared to other treatment plans 24 months after starting treatment.

2 Nov 2021

Study: Ultra-low rituximab dose maintains low disease activity for most RA patients

New research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that in one study, the majority of rheumatoid arthritis patients on an ultra-low dose of the drug rituximab maintained low disease activity for up to four years, and rarely needed to switch to other biologic drugs or glucocorticoids to control their disease.

2 Nov 2021

Dutch study compares mRNA vaccines to vector-based vaccines for COVID-19

An overview of the PIENTER-Corona (PiCo) study, which is a Dutch nationwide efficacy comparison study on four different COVID-19 vaccines.

2 Nov 2021

The pros and cons of a COVID-19 vaccine booster

The authors provide an overview of current literature available to assess the need for COVID-19 vaccine booster doses and their potential target population.

2 Nov 2021

Relaxing limits on take-home methadone did not lead to worse outcomes

Relaxing limits on take-home doses of methadone - a medication used to treat opioid addiction - does not appear to lead to worse treatment outcomes, according to a new study led by Washington State University researchers.

1 Nov 2021

Pregnant and breastfeeding women's perceptions and concerns about COVID-19 vaccines

Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination is one of the most important ways of fighting the ongoing COVID-19 pandemic, the recommendations for vaccination for pregnant and breastfeeding women are not consistent.

1 Nov 2021

Pharmaceutical News

As overdose deaths soar, DEA-wary pharmacies shy from dispensing addiction medication

Pfizer-BioNTech COVID-19 vaccine is associated with lower viral load in breakthrough infections

Hemin as a potential therapy for COVID-19

Study compares efficacy of BNT162b2 and CoronaVac as the booster dose for COVID-19 vaccination

Oral SARS-CoV-2 Mpro inhibitor for therapeutic use

Middlemen take home almost 53% of the net proceeds from insulin sales, finds study

Therapeutics that target ceramides may help treat cardiometabolic disease

Despite restraints, democrats’ drug pricing plan could still aid consumers

MHRA approves first oral antiviral for the treatment of COVID-19

Pfizer COVID-19 vaccine elicits durable specific memory T-cell response

Cuba reports 92.4 percent efficacy for 3 dose SOBERANA 02 COVID-19 vaccine

Prior SARS-CoV-2 infection and risk of breakthrough infection following mRNA vaccination

Pre-clinical follow-up study boosting with original formulation and next generation INO-4802 SARS-CoV-2 vaccine candidate

Waters and Sartorius partner to help bioprocess scientists accelerate clone selection and process development

Early combination treatment achieves clinically inactive disease in children with polyarticular JIA

Study: Ultra-low rituximab dose maintains low disease activity for most RA patients

Dutch study compares mRNA vaccines to vector-based vaccines for COVID-19

The pros and cons of a COVID-19 vaccine booster

Relaxing limits on take-home methadone did not lead to worse outcomes

Pregnant and breastfeeding women's perceptions and concerns about COVID-19 vaccines

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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