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Repurposing drugs to outsmart cancers

In an article published today by SAGE Publishing, investigators from The Nagourney Cancer Institute and The Albert Einstein Israelite Hospital in São Paulo, Brazil, announced a new approach to identifying effective treatments for patients with advanced metastatic cancers. A drug commonly used to treat kidney and liver cancer was discovered effective for breast cancer, which may open new drug therapies to patients regardless of tumor type.

22 Mar 2019

Presence of bacteria in urine does not always point to infection, shows study

Doctors should think carefully before testing patients for a urinary tract infection (UTI) to avoid over-diagnosis and unnecessary antibiotic treatment, according to updated asymptomatic bacteriuria (ASB) guidelines released by the Infectious Diseases Society of America (IDSA) and published in Clinical Infectious Diseases.

22 Mar 2019

Alzheimer's patients using antiepileptic drugs have twice the risk of pneumonia, study shows

People with Alzheimer's disease using antiepileptic drugs have twice the risk of pneumonia compared to non-users, a new study from the University of Eastern Finland shows.

21 Mar 2019

New drugs on PBS for Parkinson's, MND and Cutaneous T cell lymphoma

Under Australia's Pharmaceutical Benefits Scheme (PBS), soon many of the rare diseases and their treatments are set to become cheaper.

21 Mar 2019

FDA approves brexanolone, first drug developed to treat postpartum depression

Approximately 1 in 9 women in the United States experiences symptoms of postpartum depression, according to the Centers for Disease Control and Prevention.

21 Mar 2019

New technique detects fake drugs from video taken as sample undergoes disturbance

If we could tell authentic from counterfeit or adulterated drugs and foods just by looking at them, we could save money and lives every year, especially in the developing world, where the problem is worst.

21 Mar 2019

Innovative in vitro method to develop easy-to-swallow medicine for children and older people

Scientists at the University of Surrey and University College London have revealed an innovative in vitro method that can help to develop easy to swallow medicine for children and older people.

21 Mar 2019

Most pills contain common allergens, warn experts

Pills or oral medications contain inactive ingredients such as gluten that may be responsible for dangerous side effects, concludes a new study.

20 Mar 2019

Worryingly long wait for NHS cancer patients

Around a fourth of NHS cancer patients have to wait a worryingly long amount of time to start treatment, according to a new NHS England report.

20 Mar 2019

FDA approves first drug for treatment of postpartum depression in adult women

The U.S. Food and Drug Administration today approved Zulresso (brexanolone) injection for intravenous use for the treatment of postpartum depression in adult women. This is the first drug approved by the FDA specifically for PPD.

20 Mar 2019

Newly discovered parameters offer more control over efficient release of drugs

Researchers at Eindhoven University of Technology and Utrecht University have discovered the parameters that govern the encapsulation of drugs. This gives more control over the slow and steady release of drugs in patients.

20 Mar 2019

FDA warns marketer of unapproved products claiming to treat addiction, chronic pain

The U.S. Food and Drug Administration today posted a warning letter to Nutra Pharma Corp. for illegally marketing unapproved products labeled as homeopathic with claims about their ability to treat addiction and chronic pain, including pain associated with cancer, diabetes, shingles, fibromyalgia and other serious conditions.

19 Mar 2019

Cholesterol lowering drug can also help treat cancer-associated cachexia

Brazilian researchers have discovered that a drug regularly prescribed to control cholesterol can also be used to treat cachexia, or wasting syndrome, a condition characterized by rapid weight loss and muscle atrophy associated with extreme physical weakness.

19 Mar 2019

New electronic support system for choosing drug treatment based on patient’s genotype

The science of pharmacogenomics (PGx) studies how genetic variability affects an individual’s response to a drug. Most patients metabolize a medication as expected. But some eliminate it from the body before it can do its work, while others process it slowly, causing it to build up in the body and risk an overdose.

19 Mar 2019

Pharmacists can undertake overall clinical responsibility for patients, shows study

The first evaluation of pharmacists based in accident and emergency departments has concluded that with additional clinical skills, they are able to take on overall clinical responsibility for patients.

19 Mar 2019

Study shows ticagrelor is equally safe and effective as clopidogrel after heart attack

Patients given clot busters to treat a heart attack fared equally well if they were given the standard blood thinning medication clopidogrel versus the newer, more potent drug ticagrelor, according to research presented at the American College of Cardiology's 68thAnnual Scientific Session.

19 Mar 2019

Common medications to treat heartburn linked to increased risks for kidney failure

Common medications prescribed to treat heartburn, acid reflux and ulcers are linked to increased risks for kidney failure and chronic kidney disease, found a recent University at Buffalo study.

19 Mar 2019

Study indicates the benefits of stopping aspirin in heart attack patients

Patients who stopped taking aspirin three months after receiving a stent to open the heart's arteries but continued taking a P2Y12inhibitor—clopidogrel, prasugrel or ticagrelor—did not experience higher rates of death from any cause, heart attack or stroke after a year compared with those receiving standard therapy, according to research presented at the American College of Cardiology's 68thAnnual Scientific Session.

19 Mar 2019

Two-drug combinations containing calcium channel blocker significantly lowers BP

In the largest randomized controlled trial of treatment for high blood pressure ever conducted in sub-Saharan Africa, two frontline two-drug combinations that included the long-acting calcium channel blocker, amlodipine, were able to drive down blood pressure levels more than a third two-drug combination that did not include amlodipine, according to research presented at the American College of Cardiology's 68th Annual Scientific Session.

19 Mar 2019

A new option for reducing LDL cholesterol in patients at high risk for heart attack, stroke

Patients at high risk for a heart attack or stroke who took an investigational drug in addition to a statin had significantly lower LDL, or "bad" cholesterol, after 12 weeks compared to similar patients who took a placebo in addition to statin therapy, according to research presented at the American College of Cardiology's 68thAnnual Scientific Session.

19 Mar 2019

Pharmaceutical News

Repurposing drugs to outsmart cancers

Presence of bacteria in urine does not always point to infection, shows study

Alzheimer's patients using antiepileptic drugs have twice the risk of pneumonia, study shows

New drugs on PBS for Parkinson's, MND and Cutaneous T cell lymphoma

FDA approves brexanolone, first drug developed to treat postpartum depression

New technique detects fake drugs from video taken as sample undergoes disturbance

Innovative in vitro method to develop easy-to-swallow medicine for children and older people

Most pills contain common allergens, warn experts

Worryingly long wait for NHS cancer patients

FDA approves first drug for treatment of postpartum depression in adult women

Newly discovered parameters offer more control over efficient release of drugs

FDA warns marketer of unapproved products claiming to treat addiction, chronic pain

Cholesterol lowering drug can also help treat cancer-associated cachexia

New electronic support system for choosing drug treatment based on patient’s genotype

Pharmacists can undertake overall clinical responsibility for patients, shows study

Study shows ticagrelor is equally safe and effective as clopidogrel after heart attack

Common medications to treat heartburn linked to increased risks for kidney failure

Study indicates the benefits of stopping aspirin in heart attack patients

Two-drug combinations containing calcium channel blocker significantly lowers BP

A new option for reducing LDL cholesterol in patients at high risk for heart attack, stroke

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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