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Researchers focus on delivery of insulin in pill form

One mother vividly remembers her three-and-a-half-year-old son's pleas when he received insulin injections several times each day. "He would beg and plead, 'Don't do it Momma!'" she recalls.

29 Jun 2018

Blood pressure medications linked to increased mortality, memory problems in old and frail patients

Old and frail patients have an increased mortality risk and increased memory problems when their blood pressure is lowered too much through medication.

28 Jun 2018

LUMICKS partners with AstraZeneca, University of Cambridge to establish new 'Center of Excellence for Dynamic Single-Molecule Analysis for Accelerated Drug Discovery and Biology'

The center will be based around LUMICKS’ C-Trap™ optical tweezers–fluorescence microscope, which for the first time enables real-time observation and probing of biomolecular interactions. The approach will be pioneered in several pharmacology and biology assays with the aim of accelerating the discovery of potential new drugs.

From Lumicks 28 Jun 2018

Researchers examine whether taking a hallucinogen can curb cocaine use

Unlike with alcohol or nicotine, there is not a pharmacological option available to individuals addicted to cocaine to help them stop using the drug. However, researchers at the University of Alabama at Birmingham believe the tool to help individuals treat their addiction may very well exist.

28 Jun 2018

New heat stable version of Carbetocin to prevent hemorrhage after birth

The World Health Organization (WHO) has said that a new heat stable version of a drug Carbetocin can save lives of new mothers could “revolutionize” therapy. The results of the study looking at the effectiveness of the new version of the drug were published in the latest issue of the New England Journal of Medicine.

28 Jun 2018

FDA approves cannabis based drug for severe form of epilepsy

The U.S. Food and Drug Administration (FDA) on the 25th of June 2018 approved Epidiolex oral solution that is essentially cannabidiol or the active component of marijuana or cannabis. As of now the drug is approved for use in two rare forms of epilepsy - Lennox-Gastaut syndrome and Dravet syndrome. The approval comes for individuals over two years of age.

28 Jun 2018

Antidepressant drug appears to effectively stop progression of PBC

Gail Wright considered herself healthy. She had no idea she had a chronic liver disease. "I was at a routine check-up and my doctor said my liver enzymes were elevated. I was sent to a specialist but I wasn't too worried. I didn't have any symptoms."

27 Jun 2018

Human insulin as safe and effective as expensive insulin analogs for patients with type 2 diabetes

Patients with Type 2 diabetes who were treated with the newer generation of insulin analog drugs did not have substantially better outcomes than those treated with less costly human insulin, according to a study by Yale School of Medicine researchers and colleagues at Kaiser Permanente.

27 Jun 2018

New avenue for cancer treatment opens when one drug fails

A new class of cancer drugs – called CDK4/6 inhibitors -- recently approved to treat breast cancer can stunt the cancer's growth and replication.

27 Jun 2018

Researchers examine new influenza drug's mode of action in detail

The new influenza drug Xofluza, developed by the Japanese pharmaceutical company Shionogi, was approved for clinical use in Japan in February 2018.

26 Jun 2018

Unbiased approach reveals how to restore breast cancer drugs’ tumor-killing potential

More than 60 percent of breast cancer cases involve defects in the same biochemical chain of events within cancer cells-- known as the PI3 kinase (PI3K) pathway--but efforts to develop therapies targeting this pathway have met with little success after hundreds of mostly failed clinical trials. And researchers still don't understand why.

26 Jun 2018

Antidepressant use in people with COPD linked to increased risk of death and hospitalization

Antidepressant use in people with chronic obstructive pulmonary disease is associated with a 20 percent increase in likelihood of death and a 15 percent increase in likelihood of hospitalization due to related symptoms, finds a new study led by researchers at St. Michael's Hospital.

26 Jun 2018

FDA approves new marijuana-based drug to treat rare and severe forms of epilepsy

The U.S. Food and Drug Administration today approved Epidiolex (cannabidiol) oral solution for the treatment of seizures associated with two rare and severe forms of epilepsy, Lennox-Gastaut syndrome and Dravet syndrome, in patients two years of age and older.

25 Jun 2018

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

AntiCancer's oral drug overcomes gemcitabine resistance in mouse models of human pancreatic cancer

Pancreatic cancer is lethal in about 95% of cases mostly due to failure of first-line therapy gemcitabine. AntiCancer Inc.'s oral methioninase (AC 00619), which is in late pre-clinical development as an anti-cancer as well as an anti-aging drug, has now been shown to overcome gemcitabine resistance in mouse models of human pancreatic cancer, including AntiCancer's patient-derived orthotopic xenograft mouse models.

25 Jun 2018

Drug used to treat opioid dependence poses serious health risks in exposed children

A new study published online today by Pediatrics and conducted by researchers at the Center for Injury Research and Policy and the Central Ohio Poison Center at Nationwide Children's Hospital found that from January 2007 through December 2016 there were more than 11,000 calls to US Poison Centers for pediatric exposures to buprenorphine – a prescription opioid medication used to treat opioid use disorder.

25 Jun 2018

ABPI associated with NHS for 70 years in pharmaceutical research

In this special year, both the NHS and the Association of the British Pharmaceutical Industry are celebrating our respective 70th anniversaries. The histories of these two organizations have been inextricably linked since 1948 and our relationship with the NHS continues to go from strength to strength.

25 Jun 2018

Overdose risk increases five-fold with concurrent opioid and benzodiazepine use

In the first 90 days of concurrent opioid and benzodiazepine use, the risk of opioid-related overdose increases five-fold compared to opioid-only use among Medicare recipients, according to a new study from the University of Pittsburgh School of Pharmacy, published today in JAMA Network Open

22 Jun 2018

UC San Diego launches new bacteriophage therapy center

With microbial resistance to antibiotics growing into a major global health crisis, researchers at University of California San Diego School of Medicine, in collaboration with national research institutions and private industry, are leveraging hard-won expertise to exploit a natural viral enemy of pathogenic bacteria, creating North America's first Center for Innovative Phage Applications and Therapeutics

22 Jun 2018

New review outlines current state of sex-sensitive issues linked to heart failure drugs

Heart failure is almost as common in women as men, but its characteristics vary by sex.

22 Jun 2018

Pharmaceutical News

Researchers focus on delivery of insulin in pill form

Blood pressure medications linked to increased mortality, memory problems in old and frail patients

LUMICKS partners with AstraZeneca, University of Cambridge to establish new 'Center of Excellence for Dynamic Single-Molecule Analysis for Accelerated Drug Discovery and Biology'

Researchers examine whether taking a hallucinogen can curb cocaine use

New heat stable version of Carbetocin to prevent hemorrhage after birth

FDA approves cannabis based drug for severe form of epilepsy

Antidepressant drug appears to effectively stop progression of PBC

Human insulin as safe and effective as expensive insulin analogs for patients with type 2 diabetes

New avenue for cancer treatment opens when one drug fails

Researchers examine new influenza drug's mode of action in detail

Unbiased approach reveals how to restore breast cancer drugs’ tumor-killing potential

Antidepressant use in people with COPD linked to increased risk of death and hospitalization

FDA approves new marijuana-based drug to treat rare and severe forms of epilepsy

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

AntiCancer's oral drug overcomes gemcitabine resistance in mouse models of human pancreatic cancer

Drug used to treat opioid dependence poses serious health risks in exposed children

ABPI associated with NHS for 70 years in pharmaceutical research

Overdose risk increases five-fold with concurrent opioid and benzodiazepine use

UC San Diego launches new bacteriophage therapy center

New review outlines current state of sex-sensitive issues linked to heart failure drugs

How does norepinephrine influence anxiety-related behaviours?

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

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