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Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Researchers at Monash University and Peter MacCallum Cancer Centre have identified for the first time how a new class of epigenetic drug engages with the immune system to kill off cancer cells, offering powerful new pathways for enhanced blood cancer therapies.

1 Mar 2017

Commonly-prescribed drug for treating weak bone condition linked to increased risk of 'micro-cracks'

A type of drug used to treat weak bones is associated with an increased risk of 'micro-cracks' in bone, according to new research.

1 Mar 2017

Compound from soil bacteria could translate into new drug lead for TB

A new treatment for tuberculosis (TB) is set to be developed using compounds derived from bacteria that live in soil - according an international collaboration of researchers, including the University of Warwick.

1 Mar 2017

Study highlights need to control doping problem in amateur sports

A study led by the University of Granada has shown that doping is not only a problem exclusive to professional sports, but also occurs in amateur sports.

1 Mar 2017

METTLER TOLEDO announces online seminar focusing on crystallization scale-up

METTLER TOLEDO has announced an online seminar focusing on an industrial perspective of successful techniques to develop a scalable crystallization process – Crystallization Scale-up: An Industry Perspective.

From Mettler-Toledo International Inc. 1 Mar 2017

New BSR guideline provides evidence-based recommendations for clinicians prescribing non-biologic DMARDs

This latest guidance sets out evidence based recommendations for clinicians prescribing synthetic, non-biologic, anti-rheumatic drugs to tackle multisystem rheumatic conditions.

1 Mar 2017

WSU study aims to reduce burden of antimicrobial resistance

The death last year of a woman in Reno, Nev., from an infection resistant to every type of antibiotic available in the U.S. highlights how serious the threat of antimicrobial resistance has become.

1 Mar 2017

Novel NMR spectroscopy platform holds potential to revolutionize drug development practices

Implementation of a new nuclear magnetic resonance spectroscopy platform will provide professors Nicolas Doucet and Steven LaPlante of Centre INRS-Institut Armand-Frappier with a powerful new tool for conducting an ambitious research program aimed at identifying new therapeutic molecules.

28 Feb 2017

Study provides new insights into side effects of antipsychotics

After much deliberation and anxiety, the family finally sought psychiatric help for their son. And the results were in a way, a relief.

28 Feb 2017

Biologists develop new way to inhibit cancer cell cleanup mechanism

The genomes of cancer cells--cells that do not obey signals to stop reproducing--are riddled with genetic mutations, causing them inadvertently to make many dysfunctional proteins.

28 Feb 2017

MIT researchers develop new machine to rapidly produce customized peptides

Manufacturing small proteins known as peptides is usually very time-consuming, which has slowed development of new peptide drugs for diseases such as cancer, diabetes, and bacterial infections.

27 Feb 2017

Universal public coverage of essential medicines could save over $4 billion per year, study finds

Universal public coverage of 117 essential medicines could address the needs of most Canadians for pharmaceutical drugs, and possibly save more than $4 billion a year, according to a new study published http://www.cmaj.ca/site/press/cmaj.161082.pdf in CMAJ.

27 Feb 2017

Alzheimer's drug prescribed off-label could accelerate cognitive decline for some patients

Donepezil, a medication that is approved to treat people with Alzheimer's disease, should not be prescribed for people with mild cognitive impairment without a genetic test.

24 Feb 2017

Dietary prebiotics can improve sleep after stress exposure, study suggests

In recent years, reams of research papers have shed light on the health benefits of probiotics, the "good bacteria" found in fermented foods and dietary supplements.

24 Feb 2017

Researchers discover promising target for treatment of leishmaniasis

Each year, about 2 million people contract leishmaniasis, a parasitic disease transmitted by the bite of a sand fly. The cutaneous form of the disease results in disfiguring skin ulcers that may take months or years to heal and in rare cases can become metastatic, causing major tissue damage.

24 Feb 2017

Novel antiviral drug can protect transplant patients against CMV infections

In a significant advance in improving the safety of donor stem cell transplants, a major clinical trial led by researchers at Dana-Farber Cancer Institute and Brigham and Women's Hospital has shown that a novel agent can protect against the most common viral infection that patients face after transplantation.

24 Feb 2017

New trial examines use of nanotechnology to improve delivery of drugs to HIV patients

Successful results of a University of Liverpool-led trial that utilised nanotechnology to improve drug therapies for HIV patients has been presented at the Conference on Retroviruses and Opportunistic Infections in Seattle, a leading annual conference of HIV research, clinical practice and progress.

24 Feb 2017

Scientists devise novel DNA vaccine approach against important cancer antigen targets

Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against one of the most important cancer antigen targets. Study results were published in the journal Molecular Therapy.

24 Feb 2017

New investigational drug may help combat antibiotic-resistant global health threat

The deadly fungus, Candida auris, which has been found in hospitals, is resistant to entire classes of antimicrobial drugs, limiting treatment options for those infected.

24 Feb 2017

Researchers find link between low general cognitive ability and elevated risk of not taking statins

After a heart attack, it is important for patients to take medication that lowers cholesterol levels. In a new study published in the European Journal of Preventive Cardiology, researchers at Uppsala and Umeå Universities have found that general cognitive ability (intelligence) has a bearing, in the first year and two years after the heart attack, on how well men take statins prescribed for them.

24 Feb 2017

Pharmaceutical News

Combination of epigenetic and immune-based treatments could lead to better blood cancer therapies

Commonly-prescribed drug for treating weak bone condition linked to increased risk of 'micro-cracks'

Compound from soil bacteria could translate into new drug lead for TB

Study highlights need to control doping problem in amateur sports

METTLER TOLEDO announces online seminar focusing on crystallization scale-up

New BSR guideline provides evidence-based recommendations for clinicians prescribing non-biologic DMARDs

WSU study aims to reduce burden of antimicrobial resistance

Novel NMR spectroscopy platform holds potential to revolutionize drug development practices

Study provides new insights into side effects of antipsychotics

Biologists develop new way to inhibit cancer cell cleanup mechanism

MIT researchers develop new machine to rapidly produce customized peptides

Universal public coverage of essential medicines could save over $4 billion per year, study finds

Alzheimer's drug prescribed off-label could accelerate cognitive decline for some patients

Dietary prebiotics can improve sleep after stress exposure, study suggests

Researchers discover promising target for treatment of leishmaniasis

Novel antiviral drug can protect transplant patients against CMV infections

New trial examines use of nanotechnology to improve delivery of drugs to HIV patients

Scientists devise novel DNA vaccine approach against important cancer antigen targets

New investigational drug may help combat antibiotic-resistant global health threat

Researchers find link between low general cognitive ability and elevated risk of not taking statins

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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