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Researchers develop efficient computational method to create new drugs

Researchers of the University of Barcelona have developed a more efficient computational method to identify new drugs.

1 Dec 2016

TSRI scientists discover potential drug candidate to suppress pain and itch

In a new study, scientists from the Florida campus of The Scripps Research Institute have identified a possible drug candidate that suppresses pain and itch in animal models.

1 Dec 2016

Treatment with biosimilar drug improves progression-free survival in breast cancer patients

Among women with metastatic breast cancer, treatment with a drug that is biosimilar to the breast cancer drug trastuzumab resulted in an equivalent overall response rate at 24 weeks compared with trastuzumab, according to a study published online by JAMA.

1 Dec 2016

Liverpool-led research consortium aims to reduce mother-to-child transmission of HIV

Researchers from the University of Liverpool's Institute of Translational Medicine have been awarded a grant of up to US$ 8.9 million (GBP £5.8m) to lead a multinational research consortium that aims to reduce mother-to-child transmission of HIV.

1 Dec 2016

Combination treatment may be valuable therapeutic option for HER2-negative metastatic breast cancer

Finding the ideal combination of targeted, hormonal and chemotherapeutic agents to treat HER2-negative metastatic breast cancer has been challenging researchers for decades.

1 Dec 2016

Type 2 diabetes drug may someday help combat breast and ovarian cancers

A drug used now to treat Type 2 diabetes may someday help beat breast and ovarian cancers, but not until researchers decode the complex interactions that in some cases help promote tumors, according to Rice University scientists.

30 Nov 2016

PCSK9 and HMGCR genetic variations that lower bad cholesterol affect risk of cardiovascular events

In a new study published in the December 1, 2016 issue of The New England Journal of Medicine, researchers at Brigham and Women's Hospital, and a collaboration of international researchers, studied variants in the genes encoding HMGCR and PCSK9 that affect cholesterol levels, and found that variants that lowered LDL (or "bad") cholesterol in each gene were associated with nearly identical protective effects on the risk of cardiovascular events per unit reduction in LDL cholesterol.

30 Nov 2016

First licensed vaccine could reduce burden in regions with high-levels of dengue infection

The first licensed vaccine for the potentially life-threatening dengue virus should only be used in moderate-to high impacted regions, new research has predicted.

30 Nov 2016

Researchers use microbubbles and ultrasound to transport drugs across blood–brain barrier

The impassable blood-brain barrier prevents microorganisms from entering our brain, however it also blocks medicines that could help treat Parkinson's, Alzheimer's and other neurodegenerative diseases.

30 Nov 2016

Researchers find differences in use of prescription analgesics between people with and without Alzheimer’s disease

Approximately one third of persons with Alzheimer’s disease use prescription medicines for pain after their diagnosis, reports a recent study conducted at the University of Eastern Finland.

30 Nov 2016

Researchers find way to make changes to enzyme-driven assembly line to improve antibiotics

Researchers from North Carolina State University have discovered a way to make pinpoint changes to an enzyme-driven "assembly line" that will enable scientists to improve or change the properties of existing antibiotics as well as create designer compounds.

30 Nov 2016

Researchers come up with new approach to stabilize vaccines at room temperature

Shipping vaccines in an unbroken temperature-controlled supply chain (a "cold chain") all the way to recipients is a major logistical and financial challenge in remote areas and developing countries.

30 Nov 2016

Over-the-counter and prescription pain medications linked to drug-induced liver injury

More than 1,000 medications, with acetaminophen being the most common, have been associated with drug-induced liver injury.

30 Nov 2016

Researchers develop virtual liver model to better understand metabolism of non-prescription painkiller

Researchers at Indiana University's Biocomplexity Institute have developed a virtual model of the human liver to better understand how the organ metabolizes acetaminophen, a common non-prescription painkiller and fever-reducer used in over-the-counter drugs such as Tylenol.

29 Nov 2016

Study explores perceptions of college-age males about HPV

Maggie Pitts took great interest in the human papillomavirus vaccine after Virginia became the first state in the country to mandate its use among girls in the sixth grade.

29 Nov 2016

Study shows heart medications prevent cardiovascular damage during breast cancer treatment

Heart medication taken in combination with chemotherapy reduces the risk of serious cardiovascular damage in patients with early-stage breast cancer, according to results from a new landmark clinical trial.

29 Nov 2016

Study finds link between birth defects and antiepileptic drugs during pregnancy

A joint study conducted by researchers from the universities of Liverpool and Manchester has found a link between birth defects and certain types of epilepsy medication.

29 Nov 2016

Study sheds light on why new drug is effective in combating leukaemia

Researchers at the University of Southampton have shed new light on why and how a new class of drug is effective at fighting off leukaemia.

29 Nov 2016

Kratom may be safer and less addictive than current treatments for pain, research suggests

A delayed U.S. Drug Enforcement Administration ban on kratom would stifle scientific understanding of the herb's active chemical components and documented pharmacologic properties if implemented, according to a special report published today in The Journal of the American Osteopathic Association.

29 Nov 2016

Dirt beneath New York City may provide new weapons to fight against disease

Microbes have long been an invaluable source of new drugs. And to find more, we may have to look no further than the ground beneath our feet.

29 Nov 2016

Pharmaceutical News

Researchers develop efficient computational method to create new drugs

TSRI scientists discover potential drug candidate to suppress pain and itch

Treatment with biosimilar drug improves progression-free survival in breast cancer patients

Liverpool-led research consortium aims to reduce mother-to-child transmission of HIV

Combination treatment may be valuable therapeutic option for HER2-negative metastatic breast cancer

Type 2 diabetes drug may someday help combat breast and ovarian cancers

PCSK9 and HMGCR genetic variations that lower bad cholesterol affect risk of cardiovascular events

First licensed vaccine could reduce burden in regions with high-levels of dengue infection

Researchers use microbubbles and ultrasound to transport drugs across blood–brain barrier

Researchers find differences in use of prescription analgesics between people with and without Alzheimer’s disease

Researchers find way to make changes to enzyme-driven assembly line to improve antibiotics

Researchers come up with new approach to stabilize vaccines at room temperature

Over-the-counter and prescription pain medications linked to drug-induced liver injury

Researchers develop virtual liver model to better understand metabolism of non-prescription painkiller

Study explores perceptions of college-age males about HPV

Study shows heart medications prevent cardiovascular damage during breast cancer treatment

Study finds link between birth defects and antiepileptic drugs during pregnancy

Study sheds light on why new drug is effective in combating leukaemia

Kratom may be safer and less addictive than current treatments for pain, research suggests

Dirt beneath New York City may provide new weapons to fight against disease

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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