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Gene testing could help predict ovarian cancer patients' sensitivity to new class of drugs

Testing for a gene commonly mutated in ovarian cancers could pick out patients who will respond well to a promising new class of cancer drugs, a major new study reveals.

22 Dec 2016

TSRI scientists shed light on how antiviral drug stops influenza infections

A new study led by scientists at The Scripps Research Institute (TSRI) is the first to show exactly how the drug Arbidol stops influenza infections. The research reveals that Arbidol stops the virus from entering host cells by binding within a recessed pocket on the virus.

22 Dec 2016

Generative AAE can be radically new way to discover drugs on demand

Scientists at the Pharmaceutical Artificial Intelligence group of Insilico Medicine, Inc, today announced the publication of a seminal paper demonstrating the application of generative adversarial autoencoders (AAEs) to generating new molecular fingerprints on demand.

22 Dec 2016

TSRI scientists identify microbial natural products as abundant sources of potent anticancer drugs

Scientists from the Florida campus of The Scripps Research Institute have developed an efficient process to rapidly discover new “enediyne natural products” from soil microbes that could be further developed into extremely potent anticancer drugs.

22 Dec 2016

Majority of GPs do not offer full range of contraceptive methods to patients, survey finds

A survey of more than 1,000 GPs across England has highlighted worrying gaps in contraceptive provision.

22 Dec 2016

New research offers valuable insight for developing more effective drugs to treat IBD

Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the intestine that includes Crohn's disease and ulcerative colitis.

22 Dec 2016

New UCLA research recommends community clinics to routinely screen for misuse of drugs

The misuse of both prescription and illicit drugs is so prevalent in Tijuana and East Los Angeles that community clinics in those areas should routinely, though discreetly, screen for it, according to new UCLA research.

21 Dec 2016

Leaf-shaped prototype reactor could act as 'mini-factory' for drugs

To produce drugs sustainably and cheaply, anywhere you want. Whether in the middle of the jungle or even on Mars. A 'mini-factory' whereby sunlight can be captured to make chemical products.

21 Dec 2016

Danish researchers uncover bacteria’s secret code language

Antibiotic resistance in pathogenic bacteria is a growing global challenge. Danish researchers have now discovered that bacteria use a code language to avoid being controlled.

21 Dec 2016

Researchers engineer promising live-attenuated RSV vaccine candidate

Crafting a vaccine against RSV (respiratory syncytial virus) has been a minefield for 50 years, but scientists believe they have found the right balance.

21 Dec 2016

OPERA study evaluates patient perceptions of pain treatment with use of transdermal formulations

Clarity, a global international scientific research company, based in Austin, Texas, announces the latest results of its IRB-approved OPERA study.

21 Dec 2016

Scientists identify potential drug treatment in fight against Alzheimer’s disease

An international team of scientists has announced a new advance in the fight against Alzheimer’s disease by identifying a new drug target for not only improving symptoms of brain degeneration – but also to extend the life-span of the terminally ill mice.

21 Dec 2016

UT Southwestern researchers find new way to combat multidrug-resistant bacteria in burn injuries

A new way to fight multidrug-resistant bacteria by blinding them rather than killing them proved highly effective in a model of burn injuries, UT Southwestern Medical Center research shows.

21 Dec 2016

Breast cancer patient finds new hope with potentially revolutionary treatment

City of Hope patient Susan Young has had a remarkable response to a potentially revolutionary new treatment, a combination of the p53 cancer vaccine and a drug that blocks a specific cancer-aiding protein.

21 Dec 2016

Anticholinergic drugs linked to increased rate of emergency department and hospital visits

Anticholinergic medications, a class of drugs very commonly used by older adults, are linked to an increased rate of emergency department and hospital utilization in the United States, according to an Indiana University Center for Aging Research, Indiana University Center for Health Innovation and Implementation Science, and Regenstrief Institute study of community-dwelling Americans age 65 and older.

21 Dec 2016

Gelatin supplement consumption plus intensive exercise can help build ligaments, tendons and bones

A new study from Keith Baar's Functional Molecular Biology Laboratory at the UC Davis College of Biological Sciences and the Australian Institute of Sport suggests that consuming a gelatin supplement, plus a burst of intensive exercise, can help build ligaments, tendons and bones.

21 Dec 2016

Regular use of aspirin could cut pancreatic cancer risk in half

Regular use of aspirin by people living in Shanghai, China, was associated with decreased risk for developing pancreatic cancer, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

20 Dec 2016

Study compares medications for treatment of persons with recurrent genital herpes

In a study appearing in the December 20 issue of JAMA, Anna Wald, M.D., M.P.H., of the University of Washington & Fred Hutchinson Cancer Research Center, Seattle, and colleagues compared the medications pritelivir and valacyclovir for reducing genital herpes simplex virus shedding and lesions in persons with recurrent genital herpes.

20 Dec 2016

Bioinformatics helps identify new, untested drug combinations for treatment of breast cancer

Based on the study of cell signalling networks, the cell signals that drugs alter when they reach their target molecule, an exhaustive in silico analysis of the pairing of 64 therapeutic agents used to treat breast cancer (half already in use and the other half in clinical testing phase) has allowed researchers at the Institute for Research in Biomedicine to identify 10 new and previously untested combinations that hold potential for the treatment of breast cancer.

20 Dec 2016

Regular use of common mouthwash can help curb spread of gonorrhoea infections

A commercial brand of mouthwash that is readily available from supermarkets and pharmacies can help curb the growth of the bacteria responsible for gonorrhoea, reveals preliminary research published online in the journal Sexually Transmitted Infections.

20 Dec 2016

Pharmaceutical News

Gene testing could help predict ovarian cancer patients' sensitivity to new class of drugs

TSRI scientists shed light on how antiviral drug stops influenza infections

Generative AAE can be radically new way to discover drugs on demand

TSRI scientists identify microbial natural products as abundant sources of potent anticancer drugs

Majority of GPs do not offer full range of contraceptive methods to patients, survey finds

New research offers valuable insight for developing more effective drugs to treat IBD

New UCLA research recommends community clinics to routinely screen for misuse of drugs

Leaf-shaped prototype reactor could act as 'mini-factory' for drugs

Danish researchers uncover bacteria’s secret code language

Researchers engineer promising live-attenuated RSV vaccine candidate

OPERA study evaluates patient perceptions of pain treatment with use of transdermal formulations

Scientists identify potential drug treatment in fight against Alzheimer’s disease

UT Southwestern researchers find new way to combat multidrug-resistant bacteria in burn injuries

Breast cancer patient finds new hope with potentially revolutionary treatment

Anticholinergic drugs linked to increased rate of emergency department and hospital visits

Gelatin supplement consumption plus intensive exercise can help build ligaments, tendons and bones

Regular use of aspirin could cut pancreatic cancer risk in half

Study compares medications for treatment of persons with recurrent genital herpes

Bioinformatics helps identify new, untested drug combinations for treatment of breast cancer

Regular use of common mouthwash can help curb spread of gonorrhoea infections

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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