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FDA grants accelerated approval for Tagrisso to treat patients with advanced NSCLC

Today, the U.S. Food and Drug Administration granted accelerated approval for an oral medication to treat patients with advanced non-small cell lung cancer (NSCLC). Tagrisso (osimertinib) is now approved for patients whose tumors have a specific epidermal growth factor receptor (EGFR) mutation (T790M) and whose disease has gotten worse after treatment with other EGFR-blocking therapy.

14 Nov 2015

Analyzing potential TB vaccine

When results from a landmark tuberculosis vaccine trial in Cape Town, South Africa were published in The Lancet in February 2013, the headlines were grim, despite hopes that the trial would point toward a successful way to thwart one of the globe's biggest public health threats.

13 Nov 2015

Measles vaccination plays key role in reducing child mortality

The number of measles-related deaths has decreased 79% from 546 800 at the beginning of the century to 114 900 in 2014. New data released by WHO for the Measles & Rubella Initiative, estimates that 17.1 million lives have been saved since 2000, largely due to increased vaccination coverage against this highly contagious viral disease.

13 Nov 2015

Experimental drug candidate aimed at combating Alzheimer's disease has anti-aging effects

Salk Institute researchers have found that an experimental drug candidate aimed at combating Alzheimer's disease has a host of unexpected anti-aging effects in animals.

13 Nov 2015

TGen: PPF drug could help treat patients with deadly brain cancer

In a significant breakthrough, the Translational Genomics Research Institute has identified a drug, propentofylline or PPF, that could help treat patients with deadly brain cancer.

13 Nov 2015

Vanderbilt study could lead to development of new drugs that relieve pain without causing vascular effects

It's been about a decade since the promise of COX-2 inhibitors -- drugs that relieve arthritis pain and inflammation without the gastrointestinal side effects of other painkillers -- was tempered by the realization that they could cause heart problems in some patients.

13 Nov 2015

Less effective drugs can help beat malaria more effectively

Oxford University scientists have found that the more effective way to beat malaria is to use less effective drugs some of the time.

13 Nov 2015

Drug combination produces long-term responses in patients with mantle cell lymphoma

New research from Moffitt Cancer Center and its collaborators find that the drug combination rituximab plus lenalidomide was effective and produced long-term responses in patients with mantle cell lymphoma.

13 Nov 2015

Personalized approach to treating side-effects of chemotherapy better for cancer patients

A new research study led by Dr. Mark Clemons, oncologist and associate cancer research scientist at The Ottawa Hospital, has shown that a personalized approach to treating one of the most expected side-effects of chemotherapy is far more effective than the existing "one size fits all" set of guidelines.

13 Nov 2015

FixHepC Buyers Club exposes weakness in Australian healthcare, assists patients to import life saving medication

In one of the greatest advances in medicine in decades, Hepatitis C is now largely curable. Over 200,000 Australians suffer from Hepatitis C. However the US manufacturer, Gilead Sciences Inc is attempting to charge the PBS $84,000 for a 12 week course of medication that costs under $200 dollars to manufacture.

13 Nov 2015

New research uncovers antibiotic prescription trends across England

New research by Antibiotic Research UK, the world’s first charity created to develop new antibiotics in the fight against superbugs, and high-performance analytic database company EXASOL has discovered that while the number of antibiotic prescriptions is coming down across England, GP practices in the most deprived parts of the country are prescribing 20% more and, worryingly, antibiotic prescriptions are on the increase in these deprived areas.

12 Nov 2015

Ovarian cancer patients with a history of oral contraceptive use have better outcomes

Patients who develop ovarian cancer appear to have better outcomes if they have a history of oral contraceptive use, according to a study by Mayo Clinic researchers published in the current issue of the journal BMC Cancer.

12 Nov 2015

MD Anderson study reveals why chemotherapy drugs not effective for many pancreatic cancer patients

A study at The University of Texas MD Anderson Cancer Center may explain why chemotherapy drugs such as gemcitabine are not effective for many pancreatic cancer patients, and perhaps point to new approaches to treatment including enhancing gemcitabine's ability to stop tumor growth.

12 Nov 2015

Certain antibiotic treatment for MRSA may potentially make patients sicker

A new study sheds light on how treatment of the "superbug" known as MRSA with certain antibiotics can potentially make patients sicker. The findings by Cedars-Sinai scientists, published today in the journal Cell Host & Microbe, could have implications for managing the bug, a virulent form of the common staph infection that can be difficult to control.

12 Nov 2015

Tocilizumab drug offers potential treatment for patients with polymyalgia rheumatics

A drug approved to treat rheumatoid arthritis, tocilizumab (Actemra, Genentech), is a potential new therapy for patients with polymyalgia rheumatica, according to an open-label, phase II study presented at the annual meeting of the American College of Rheumatology/Association of Rheumatology Health Professionals on November 10.

11 Nov 2015

Medicines do not degrade after being stored in space, shows study

The results of an opportunistic, pilot-scale study led by Virginia Wotring of the Center for Space Medicine and Department of Pharmacology at Baylor College of Medicine in the US suggest that medication degradation on the International Space Station (ISS) does not differ from what is typically seen on Earth.

11 Nov 2015

Cotellic (cobimetinib) approved to be used in combination with vemurafenib for melanoma treatment

The U.S. Food and Drug Administration today approved Cotellic (cobimetinib) to be used in combination with vemurafenib to treat advanced melanoma that has spread to other parts of the body or can't be removed by surgery, and that has a certain type of abnormal gene (BRAF V600E or V600K mutation).

10 Nov 2015

New Haven Pharmaceuticals' DURLAZA drug delivers sustained antiplatelet control for full 24 hours

New Haven Pharmaceuticals, Inc. today announced new study data that shows the company's FDA-approved drug DURLAZA delivers sustained antiplatelet control for a full 24-hour period in high-risk patients.

10 Nov 2015

Perrigo receives FDA approval for generic version of KlorCon extended-release tablets

Perrigo Company plc today announced it has received an AB therapeutic equivalent rating and final U.S. Food and Drug Administration approval for the generic version of KlorCon extended-release tablets (600 mg and 750 mg), manufactured by Upsher-Smith Laboratories, Inc., and marketed by Sandoz Pharmaceuticals, Inc.

10 Nov 2015

New findings reveal association between colorectal cancer and melanoma drug treatment

Veteran cancer reseacher Prof. Emeritus Alexander Levitzki of Hebrew University of Jerusalem says new findings show link between colorectal cancer and melanoma drug treatment knoqwn as "NT157" in two recently published studies in journal, "Ocogene."

10 Nov 2015

Pharmaceutical News

FDA grants accelerated approval for Tagrisso to treat patients with advanced NSCLC

Analyzing potential TB vaccine

Measles vaccination plays key role in reducing child mortality

Experimental drug candidate aimed at combating Alzheimer's disease has anti-aging effects

TGen: PPF drug could help treat patients with deadly brain cancer

Vanderbilt study could lead to development of new drugs that relieve pain without causing vascular effects

Less effective drugs can help beat malaria more effectively

Drug combination produces long-term responses in patients with mantle cell lymphoma

Personalized approach to treating side-effects of chemotherapy better for cancer patients

FixHepC Buyers Club exposes weakness in Australian healthcare, assists patients to import life saving medication

New research uncovers antibiotic prescription trends across England

Ovarian cancer patients with a history of oral contraceptive use have better outcomes

MD Anderson study reveals why chemotherapy drugs not effective for many pancreatic cancer patients

Certain antibiotic treatment for MRSA may potentially make patients sicker

Tocilizumab drug offers potential treatment for patients with polymyalgia rheumatics

Medicines do not degrade after being stored in space, shows study

Cotellic (cobimetinib) approved to be used in combination with vemurafenib for melanoma treatment

New Haven Pharmaceuticals' DURLAZA drug delivers sustained antiplatelet control for full 24 hours

Perrigo receives FDA approval for generic version of KlorCon extended-release tablets

New findings reveal association between colorectal cancer and melanoma drug treatment

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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