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IMBRUVICA (ibrutinib) wins Prix Galien USA 2015 Award in Best Pharmaceutical Agent category

Today, IMBRUVICA (ibrutinib) was awarded the prestigious Prix Galien USA 2015 Award in the category of Best Pharmaceutical Agent. The Prix Galien Award is considered to be the industry's highest accolade and recognizes the vital technical, scientific and clinical research skills necessary to develop medicines.

28 Oct 2015

Amount of anesthetic needed for general anesthesia during surgery varies widely

The amount of anesthetic required for general anesthesia during surgery varies widely from patient to patient and some may be able to receive a lower dose than typically administered, suggests a study being presented at the ANESTHESIOLOGY® 2015 annual meeting.

28 Oct 2015

New generation of incretin-based medicines allows coordinated action against diabesity

The new generation of incretin-based medicines will allow a coordinated action against the combination diabetes/obesity, also known as diabesity, in some cases with only a single weekly dose, and with the likelihood of additional beneficial effects on other health complications related to this condition, such as cardiovascular and neurodegenerative diseases.

28 Oct 2015

Common heartburn, acid reflux drugs may increase risk for developing kidney disease

Certain medications commonly used to treat heartburn and acid reflux may have damaging effects on the kidneys, according to two studies that will be presented at ASN Kidney Week 2015 November 3–8 at the San Diego Convention Center in San Diego, CA. The drugs, proton pump inhibitors (PPIs), are among the top 10 class of prescribed medications in the United States.

28 Oct 2015

Stopping cholesterol medications before surgery may increase risk of death during recovery

Patients who stop taking cholesterol medications before surgery are following outdated recommendations, and significantly increasing their risk of death if they don't resume taking the medications within two days after surgery, according to a study of more than 300,000 patients being presented at the ANESTHESIOLOGY 2015 annual meeting.

28 Oct 2015

Wyss Institute, UMass team up to develop drug-device combination for treating blood clots in stroke patients

Scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard University developing novel nanotherapeutics for clearing obstructed blood vessels have teamed up with researchers at University of Massachusetts' New England Center for Stroke Research (NECSTR) to develop a new, highly effective drug-device combination for treating life-threatening blood clots in patients with stroke.

28 Oct 2015

Researchers compare effectiveness of combination therapy for black patients with asthma

Among black adults with asthma treated with an inhaled corticosteroid, adding a long-acting beta-agonist did not improve the time to an asthma exacerbation compared with adding the anticholinergic tiotropium, according to a study in the October 27 issue of JAMA.

28 Oct 2015

Praziquantel treatment safe for pregnant women after first trimester

A study by Rhode Island Hospital researchers confirmed that a drug used to treat a disease afflicting millions of people in developing countries is safe to give pregnant women following their first trimester. The finding could prove critical to the care of pregnant women and lactating women with schistosomiasis, a disease caused by a parasitic worm, who were denied the drug out of concern for their health and the health of their fetuses.

28 Oct 2015

WSU collaborates with Botanisol to study and develop new anti-inflammatory drug

Work on a new anti-inflammatory drug developed from the medicinal/spice plant turmeric recently received funding from a $225,000 grant from the National Institutes of Health National Center for Complementary and Integrative Health.

28 Oct 2015

Oral formulation of insulin shows promise in management of blood glucose in diabetic rats

An intestinal patch device containing insulin that can be swallowed in the form of a capsule, in development by researchers at University of California Santa Barbara, has demonstrated efficacy of blood glucose management in diabetic rats. This work is being presented Oct. 27 at the 2015 American Association of Pharmaceutical Scientists Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in Orlando, Fla. Oct. 25-29.

28 Oct 2015

Lithium chloride could offer effective treatment against osteoarthritis

Bioengineers from Queen Mary University of London have shown for the first time that lithium chloride, a common drug used to treat mental health disorders, could offer an effective treatment against osteoarthritis by disrupting the length of the cells' antennae called primary cilia.

28 Oct 2015

Australian researchers find a way to boost cross-protective capabilities of influenza A vaccine

Australian researchers have found a way to boost the effectiveness and cross-protective capabilities of an influenza A vaccine by adding a simple component. Published this week in mBio, an online open-access journal of the American Society for Microbiology, the research in mice could lead to better seasonal flu vaccines for humans, and also vaccines that could provide community protection in the early stages of an outbreak of a novel flu virus strain.

28 Oct 2015

Imlygic approved for treatment of melanoma lesions in the skin and lymph nodes

The U.S. Food and Drug Administration today approved Imlygic (talimogene laherparepvec), the first FDA-approved oncolytic virus therapy, for the treatment of melanoma lesions in the skin and lymph nodes.

28 Oct 2015

Entry of eleven novel therapies expected to drive NSCLC market's growth to $12.7 billion in 2024

Decision Resources Group finds that the entry of eleven novel therapies into the non-small-cell lung cancer (NSCLC) market will drive the market's growth from $5.4 billion in 2014 to $12.7 billion in 2024.

27 Oct 2015

Mylan announces U.S. launch of generic Fusilev for Injection

Mylan N.V. today announced the U.S. launch of Levoleucovorin Calcium Injection 10 mg (base)/mL; 175 mg (base)/17.5 mL and 250 mg (base)/25 mL Single-use Vials, which is the generic version of Spectrum Pharmaceuticals' Fusilev for Injection.

27 Oct 2015

Oxytocin treatment improves social, emotional and behavioral problems among young kids with autism

A five week treatment with the synthetic hormone oxytocin significantly improved social, emotional and behavioral issues among young children with autism, according to University of Sydney research published today in Molecular Psychiatry.

27 Oct 2015

New drug combination may be effective against malignant melanoma

A team of Massachusetts General Hospital investigators has discovered a new combination of drugs that may be effective against one of the deadliest cancers, malignant melanoma. The combination - pairing a drug targeted against mutations in the BRAF gene with a second drug that targets another important signaling pathway - was discovered through one of the largest screens of cancer drug combinations conducted to date.

27 Oct 2015

Ipsen, EpiVax partner to create next generation botulinum neurotoxin and TSI therapeutics

Ipsen and the US company EpiVax, Inc. today announced that they have completed a collaborative project that provides a novel approach for creating next generation botulinum neurotoxin (BoNT) and Targeted Secretion Inhibitor (TSI) therapeutics.

27 Oct 2015

Patients with treatment-resistant autoimmune blood conditions may benefit from sirolimus

The immunosuppressant sirolimus is an effective and safe steroid-sparing therapy for children and young adults with highly treatment-resistant autoimmune blood conditions, according to a study published online today in Blood, the Journal of the American Society of Hematology.

27 Oct 2015

Nanofiber hydrogel infused with snake venom may stop bleeding, protect wounds

A nanofiber hydrogel infused with snake venom may be the best material to stop bleeding quickly, according to Rice University scientists.

27 Oct 2015

Pharmaceutical News

IMBRUVICA (ibrutinib) wins Prix Galien USA 2015 Award in Best Pharmaceutical Agent category

Amount of anesthetic needed for general anesthesia during surgery varies widely

New generation of incretin-based medicines allows coordinated action against diabesity

Common heartburn, acid reflux drugs may increase risk for developing kidney disease

Stopping cholesterol medications before surgery may increase risk of death during recovery

Wyss Institute, UMass team up to develop drug-device combination for treating blood clots in stroke patients

Researchers compare effectiveness of combination therapy for black patients with asthma

Praziquantel treatment safe for pregnant women after first trimester

WSU collaborates with Botanisol to study and develop new anti-inflammatory drug

Oral formulation of insulin shows promise in management of blood glucose in diabetic rats

Lithium chloride could offer effective treatment against osteoarthritis

Australian researchers find a way to boost cross-protective capabilities of influenza A vaccine

Imlygic approved for treatment of melanoma lesions in the skin and lymph nodes

Entry of eleven novel therapies expected to drive NSCLC market's growth to $12.7 billion in 2024

Mylan announces U.S. launch of generic Fusilev for Injection

Oxytocin treatment improves social, emotional and behavioral problems among young kids with autism

New drug combination may be effective against malignant melanoma

Ipsen, EpiVax partner to create next generation botulinum neurotoxin and TSI therapeutics

Patients with treatment-resistant autoimmune blood conditions may benefit from sirolimus

Nanofiber hydrogel infused with snake venom may stop bleeding, protect wounds

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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