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Researchers compare effectiveness of combination therapy for black patients with asthma

Among black adults with asthma treated with an inhaled corticosteroid, adding a long-acting beta-agonist did not improve the time to an asthma exacerbation compared with adding the anticholinergic tiotropium, according to a study in the October 27 issue of JAMA.

28 Oct 2015

Praziquantel treatment safe for pregnant women after first trimester

A study by Rhode Island Hospital researchers confirmed that a drug used to treat a disease afflicting millions of people in developing countries is safe to give pregnant women following their first trimester. The finding could prove critical to the care of pregnant women and lactating women with schistosomiasis, a disease caused by a parasitic worm, who were denied the drug out of concern for their health and the health of their fetuses.

28 Oct 2015

WSU collaborates with Botanisol to study and develop new anti-inflammatory drug

Work on a new anti-inflammatory drug developed from the medicinal/spice plant turmeric recently received funding from a $225,000 grant from the National Institutes of Health National Center for Complementary and Integrative Health.

28 Oct 2015

Oral formulation of insulin shows promise in management of blood glucose in diabetic rats

An intestinal patch device containing insulin that can be swallowed in the form of a capsule, in development by researchers at University of California Santa Barbara, has demonstrated efficacy of blood glucose management in diabetic rats. This work is being presented Oct. 27 at the 2015 American Association of Pharmaceutical Scientists Annual Meeting and Exposition, the world's largest pharmaceutical sciences meeting, in Orlando, Fla. Oct. 25-29.

28 Oct 2015

Lithium chloride could offer effective treatment against osteoarthritis

Bioengineers from Queen Mary University of London have shown for the first time that lithium chloride, a common drug used to treat mental health disorders, could offer an effective treatment against osteoarthritis by disrupting the length of the cells' antennae called primary cilia.

28 Oct 2015

Australian researchers find a way to boost cross-protective capabilities of influenza A vaccine

Australian researchers have found a way to boost the effectiveness and cross-protective capabilities of an influenza A vaccine by adding a simple component. Published this week in mBio, an online open-access journal of the American Society for Microbiology, the research in mice could lead to better seasonal flu vaccines for humans, and also vaccines that could provide community protection in the early stages of an outbreak of a novel flu virus strain.

28 Oct 2015

Imlygic approved for treatment of melanoma lesions in the skin and lymph nodes

The U.S. Food and Drug Administration today approved Imlygic (talimogene laherparepvec), the first FDA-approved oncolytic virus therapy, for the treatment of melanoma lesions in the skin and lymph nodes.

28 Oct 2015

Entry of eleven novel therapies expected to drive NSCLC market's growth to $12.7 billion in 2024

Decision Resources Group finds that the entry of eleven novel therapies into the non-small-cell lung cancer (NSCLC) market will drive the market's growth from $5.4 billion in 2014 to $12.7 billion in 2024.

27 Oct 2015

Mylan announces U.S. launch of generic Fusilev for Injection

Mylan N.V. today announced the U.S. launch of Levoleucovorin Calcium Injection 10 mg (base)/mL; 175 mg (base)/17.5 mL and 250 mg (base)/25 mL Single-use Vials, which is the generic version of Spectrum Pharmaceuticals' Fusilev for Injection.

27 Oct 2015

Oxytocin treatment improves social, emotional and behavioral problems among young kids with autism

A five week treatment with the synthetic hormone oxytocin significantly improved social, emotional and behavioral issues among young children with autism, according to University of Sydney research published today in Molecular Psychiatry.

27 Oct 2015

New drug combination may be effective against malignant melanoma

A team of Massachusetts General Hospital investigators has discovered a new combination of drugs that may be effective against one of the deadliest cancers, malignant melanoma. The combination - pairing a drug targeted against mutations in the BRAF gene with a second drug that targets another important signaling pathway - was discovered through one of the largest screens of cancer drug combinations conducted to date.

27 Oct 2015

Ipsen, EpiVax partner to create next generation botulinum neurotoxin and TSI therapeutics

Ipsen and the US company EpiVax, Inc. today announced that they have completed a collaborative project that provides a novel approach for creating next generation botulinum neurotoxin (BoNT) and Targeted Secretion Inhibitor (TSI) therapeutics.

27 Oct 2015

Patients with treatment-resistant autoimmune blood conditions may benefit from sirolimus

The immunosuppressant sirolimus is an effective and safe steroid-sparing therapy for children and young adults with highly treatment-resistant autoimmune blood conditions, according to a study published online today in Blood, the Journal of the American Society of Hematology.

27 Oct 2015

Nanofiber hydrogel infused with snake venom may stop bleeding, protect wounds

A nanofiber hydrogel infused with snake venom may be the best material to stop bleeding quickly, according to Rice University scientists.

27 Oct 2015

Advanced pancreatic cancer patients now have access to new FDA-approved drug, Onivyde

Patients with advanced pancreatic cancer now have access to the new FDA approved drug, Onivyde, that produced significant overall survival rates in an international clinical study conducted in part by researchers at HonorHealth Research Institute and the Translational Genomics Research Institute.

27 Oct 2015

Future Medicinal Chemistry releases themed issue higlighting the Academic Drug Discovery conference

Future Medicinal Chemistry, a leading MEDLINE-indexed journal published by Future Science Group, has released a themed issue dedicated to providing coverage of the presentations that took place at the 2015 Academic Drug Discovery Conference (Cambridge, UK), organized by SelectBio.

26 Oct 2015

Scalable production of gene therapy vectors: an interview with Frank Ubags

Gene therapy involves introducing genetic material into cells to replace missing or malfunctioning genes or to add a gene to express a beneficial protein in order to treat certain diseases, such as cancer or inherited disorders.

26 Oct 2015

Study: Pediatric patients prescribed more opioid medication than necessary following surgery

Although it is not uncommon for pediatric patients to be prescribed opioids to treat certain types of moderate to severe pain, new research suggests these patients may be prescribed more opioids than necessary following surgery. A study presented at the ANESTHESIOLOGY 2015 annual meeting found nearly 60 percent of opioids dispensed to pediatric patients following surgery remained unused, which could lead to the unused medication being abused by other adolescents in the household.

26 Oct 2015

Magnesium sulfate has protective effect on maternal fever during labor

Women who received magnesium sulfate during labor were less likely to develop maternal fever, a condition that can lead to a variety of complications in newborns including difficulty breathing, seizures, cerebral palsy and a condition known as "floppy baby syndrome," characterized by inadequate muscle tone, according to a retrospective study presented at the ANESTHESIOLOGY 2015 annual meeting in San Diego.

26 Oct 2015

Benzodiazepines and related drugs frequently used before and after diagnosis of Alzheimer's disease

Benzodiazepines and related drugs are initiated frequently in persons with Alzheimer's disease already before the diagnosis, and their use becomes even more common after the diagnosis, shows a recent study from the University of Eastern Finland.

26 Oct 2015

Pharmaceutical News

Researchers compare effectiveness of combination therapy for black patients with asthma

Praziquantel treatment safe for pregnant women after first trimester

WSU collaborates with Botanisol to study and develop new anti-inflammatory drug

Oral formulation of insulin shows promise in management of blood glucose in diabetic rats

Lithium chloride could offer effective treatment against osteoarthritis

Australian researchers find a way to boost cross-protective capabilities of influenza A vaccine

Imlygic approved for treatment of melanoma lesions in the skin and lymph nodes

Entry of eleven novel therapies expected to drive NSCLC market's growth to $12.7 billion in 2024

Mylan announces U.S. launch of generic Fusilev for Injection

Oxytocin treatment improves social, emotional and behavioral problems among young kids with autism

New drug combination may be effective against malignant melanoma

Ipsen, EpiVax partner to create next generation botulinum neurotoxin and TSI therapeutics

Patients with treatment-resistant autoimmune blood conditions may benefit from sirolimus

Nanofiber hydrogel infused with snake venom may stop bleeding, protect wounds

Advanced pancreatic cancer patients now have access to new FDA-approved drug, Onivyde

Future Medicinal Chemistry releases themed issue higlighting the Academic Drug Discovery conference

Scalable production of gene therapy vectors: an interview with Frank Ubags

Study: Pediatric patients prescribed more opioid medication than necessary following surgery

Magnesium sulfate has protective effect on maternal fever during labor

Benzodiazepines and related drugs frequently used before and after diagnosis of Alzheimer's disease

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Digital pathology and the PathoVerse: A conversation with Dr. Singh

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