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Researchers reveal how melanoma becomes resistant to promising new drug combo therapy

In a new study led by UCLA Jonsson Comprehensive Cancer Center member Dr. Roger Lo, researchers have uncovered how melanoma becomes resistant to a promising new drug combo therapy utilizing BRAF+MEK inhibitors in patients after an initial period of tumor shrinkage.

16 Jan 2015

Study: Century-old drug may help treat autism

Autism spectrum disorders (ASD) affect 1 to 2 percent of children in the United States. Hundreds of genetic and environmental factors have been shown to increase the risk of ASD. Researchers at UC San Diego School of Medicine previously reported that a drug used for almost a century to treat trypanosomiasis, or sleeping sickness, reversed environmental autism-like symptoms in mice.

16 Jan 2015

AbbVie gets European Commission's approval to market VIEKIRAX + EXVIERA for HCV treatment

AbbVie announced that the European Commission has granted marketing authorizations for its all-oral, short-course, interferon-free treatment of VIEKIRAX (ombitasvir/paritaprevir/ritonavir tablets) + EXVIERA (dasabuvir tablets). The treatment has been approved with or without ribavirin (RBV) for patients with genotype 1 (GT1) chronic hepatitis C virus (HCV) infection, including those with compensated liver cirrhosis, HIV-1 co-infection, patients on opioid substitution therapy and liver transplant recipients.

16 Jan 2015

Endocrine Society issues guideline on prescribing drugs to manage obesity, promote weight loss

The Endocrine Society today issued a Clinical Practice Guideline (CPG) on strategies for prescribing drugs to manage obesity and promote weight loss.

16 Jan 2015

Report: Folic acid saves babies from neural tube defects

Fortifying grain foods with the B vitamin folic acid has saved about 1,300 babies every year from being born with serious birth defects of the brain and spine known as neural tube defects (NTDs), according to new data published by the US Centers for Disease Control and Prevention in its publication Morbidity and Mortality Weekly Report.

16 Jan 2015

New study finds no correlation between opioids administered in the ER and patient satisfaction scores

A new study co-authored by investigators at the University of Massachusetts Medical School found that there is no correlation between opioids administered in the emergency room setting and Press Ganey ED patient satisfaction scores, one of the most commonly used metrics for measuring patient satisfaction.

16 Jan 2015

MRIGlobal awarded $54 million NIH contract to provide support for drug development

MRIGlobal today announced that it has been awarded a $54 million, 10-year program from the National Institute of Neurological Disorders and Stroke to provide support for the development and manufacturing of drug candidates for ultimate use in human clinical trials.

15 Jan 2015

China Jo-Jo Drugstores opens eight new retail pharmacies in Hangzhou

China Jo-Jo Drugstores, Inc., a leading China-based retail and wholesale distributor of pharmaceutical and health care products through its own online and retail pharmacies, announced today that it opened eight new retail pharmacies in Hangzhou on January 10, 2015, a company record for same-day store openings.

15 Jan 2015

Endocrinology Network offers up-to-date coverage of SGLT2 inhibitors

UBM Medica US announces that Endocrinology Network, a leading online community for endocrinologists and other clinicians who treat patients with T2DM offers comprehensive and up-to-date coverage of the sodium glucose cotransporter 2 (SGLT2) inhibitors.

15 Jan 2015

BellBrook Labs announces launch of new Transcreener UDP TR-FRET Assay

BellBrook Labs, a leader in high throughput screening assays for drug discovery, announced the launch of a TR-FRET (time resolved Forster resonance energy transfer) version of the company's Transcreener UDP Assay, a high throughput screening assay for glycosyltransferases and other UDP-producing enzymes.

15 Jan 2015

Scientists identify first genetic marker linked to severe neurological toxicity

Paclitaxel is a chemotherapeutic drug that has been shown to be highly effective when treating solid tumours, such as breast, ovarian and lung tumours. However, its use frequently causes peripheral neuropathies, neurological problems that affect the vast majority of patients.

15 Jan 2015

GSU researchers discover how steroids use a novel 'trick' to suppress inflammation

A new "trick" steroids use to suppress inflammation, which could be used to make new anti-inflammatory drugs without the harmful side effects of steroids, has been discovered by researchers at Georgia State University.

15 Jan 2015

European countries implement ATOME project to study improved access to essential painkillers

Governments in 12 European countries are to implement the recommendations of research into why more patients are not receiving essential painkillers.

15 Jan 2015

Crown's first European symposium to focus on use of Translational Platforms in oncology drug discovery

Crown Bioscience, Inc., a leading global drug discovery and development service company, has announced its first European symposium, detailing the use of Translational Platforms including Patient-Derived Xenograft (PDX) models in oncology drug discovery and development. The conference will be held on Wednesday 11th February, at the headquarters of One Nucleus in Cambridge, UK and will welcome experts from renowned pharmaceutical companies and prominent academics working in oncology.

15 Jan 2015

Study suggests that antibiotics may help fight norovirus

Antibiotics aren't supposed to be effective against viruses. But new evidence in mice suggests antibiotics may help fight norovirus, a highly contagious gastrointestinal virus, report scientists at Washington University School of Medicine in St. Louis.

14 Jan 2015

Universal vaccine against flu may be on the horizon, say researchers

The fact that this year's flu shot is not a good match against this year's influenza strain is well known, and has happened before.

14 Jan 2015

3SBio, PharmAbcine sign licensing agreement to develop and market DIG-KT

3SBio Inc., a leading China-based biotechnology company focused on researching, developing, manufacturing and marketing biopharmaceutical products, today announced it has entered into an exclusive licensing deal with PharmAbcine Inc. for the development, manufacturing and marketing of DIG-KT, a bi-specific monoclonal antibody ("mAb") targeting both VEGFR2/KDR and Tie-2 pathways for cancer in the territory of Greater China (including mainland China, Taiwan, Hong Kong and Macau) and Korea.

14 Jan 2015

Antibiotic resistance remains a serious health problem in Australia, warns NPS MedicineWise

In light of a major breakthrough in the quest to find new antibiotics with the discovery of teixobactin, NPS MedicineWise warns that antibiotic resistance in Australia remains a serious health problem we all need to work to address.

14 Jan 2015

Using MDRS to accelerate deformulation: a new whitepaper from Malvern Instruments

A new whitepaper from Malvern Panalytical on Oral Solid Dose (OSD) deformulation demonstrates how the analytical technique of Morphologically Directed Raman Spectroscopy (MDRS) can be used to accelerate the development of generic products to a successful conclusion.

From Malvern Panalytical 13 Jan 2015

Digital healthcare communications: an interview with David Hunt, CEO of HAVAS LYNX Europe

Digital has excited the industry, it has hinted at a brighter future, a potential competitive advantage and most importantly a better purpose, however like many others, it has not been the revolution it might have been.

13 Jan 2015

Pharmaceutical News

Researchers reveal how melanoma becomes resistant to promising new drug combo therapy

Study: Century-old drug may help treat autism

AbbVie gets European Commission's approval to market VIEKIRAX + EXVIERA for HCV treatment

Endocrine Society issues guideline on prescribing drugs to manage obesity, promote weight loss

Report: Folic acid saves babies from neural tube defects

New study finds no correlation between opioids administered in the ER and patient satisfaction scores

MRIGlobal awarded $54 million NIH contract to provide support for drug development

China Jo-Jo Drugstores opens eight new retail pharmacies in Hangzhou

Endocrinology Network offers up-to-date coverage of SGLT2 inhibitors

BellBrook Labs announces launch of new Transcreener UDP TR-FRET Assay

Scientists identify first genetic marker linked to severe neurological toxicity

GSU researchers discover how steroids use a novel 'trick' to suppress inflammation

European countries implement ATOME project to study improved access to essential painkillers

Crown's first European symposium to focus on use of Translational Platforms in oncology drug discovery

Study suggests that antibiotics may help fight norovirus

Universal vaccine against flu may be on the horizon, say researchers

3SBio, PharmAbcine sign licensing agreement to develop and market DIG-KT

Antibiotic resistance remains a serious health problem in Australia, warns NPS MedicineWise

Using MDRS to accelerate deformulation: a new whitepaper from Malvern Instruments

Digital healthcare communications: an interview with David Hunt, CEO of HAVAS LYNX Europe

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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