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Cumberland initiates clinical development of Boxaban (ifetroban) oral capsule for AERD treatment

Cumberland Pharmaceuticals Inc. today announced an expansion of its pipeline with a new Phase II development program. The Company has initiated the clinical development of Boxaban (ifetroban) oral capsule for the treatment of aspirin-exacerbated respiratory disease (AERD).

11 Feb 2015

ADDF, Pfizer's CTI collaborate to advance development of new drugs for Alzheimer's disease

The Alzheimer's Drug Discovery Foundation and Pfizer's Centers for Therapeutic Innovation announced today a collaboration designed to advance the development of new small-molecule drugs for Alzheimer's disease and related dementias. As part of the first-of-its kind collaboration in Alzheimer's, the ADDF and CTI will jointly invest in translational research projects, with a focus on novel Alzheimer's drug targets.

11 Feb 2015

Carma Laboratories' NEW Carmex Cold Sore Treatment named 2015 'Product of the Year' winner

Carma Laboratories, Inc., the manufacturer of Carmex lip balm products, is pleased to announce that its NEW Carmex Cold Sore Treatment has been named the 2015 "Product of the Year" winner in the Specialty Skin Treatment category by Product of the Year USA – the nation's largest consumer survey on product innovation.

11 Feb 2015

Oncolytics' REOLYSIN receives FDA Orphan Drug Designation for treatment of ovarian cancer

Oncolytics Biotech Inc., a clinical-stage biotechnology company focused on the development of oncolytic viruses as potential cancer therapeutics, today announced that the U.S. Food and Drug Administration has granted Orphan Drug Designation for its lead product candidate, REOLYSIN, for the treatment of ovarian cancer.

11 Feb 2015

ATA recommends daily serving of iodine in multivitamin/mineral supplements for pregnant, breastfeeding women

The American Thyroid Association has championed the effort to include a daily serving of iodine in multivitamin/mineral supplements intended for pregnant and breastfeeding women, and it applauds the new guidelines released by the U.S. Council for Responsible Nutrition advising manufacturers to include 150 micrograms of iodine to these daily supplements.

11 Feb 2015

Researchers close to novel therapy to treat levodopa-induced dyskinesia

Involuntary dyskinetic movements induced by treatment with levodopa (L-dopa) are a common problem for people with Parkinson's disease. Now, however, researchers at Karolinska Institutet and Lund University in Sweden seem to be close to a novel therapy to this distressing side effect.

11 Feb 2015

OSU researchers discover impact of antibiotics on microorganisms that live in animal's gut

Researchers at Oregon State University have discovered that antibiotics have an impact on the microorganisms that live in an animal's gut that's more broad and complex than previously known.

11 Feb 2015

Study shows low-dose oral iron supplementation after blood donation reduces hemoglobin recovery time

Among blood donors with normal hemoglobin levels, low-dose oral iron supplementation, compared with no supplementation, reduced the time to recovery of the postdonation decrease in hemoglobin concentration in donors with low or higher levels of a marker of overall iron storage (ferritin), according to a study in the February 10 issue of JAMA.

11 Feb 2015

Researchers suggest significant relationship between cannabis use and mania symptoms

Researchers from the University of Warwick have found evidence to suggest a significant relationship between cannabis use and the onset and exacerbation of mania symptoms.

11 Feb 2015

Experimental Ebola virus medication shows promise in monkeys

An experimental medication that targets a protein in Ebola virus called VP24 protected 75% of a group of monkeys that were studied from Ebola virus infection, according to new research conducted by the U.S. Army, in collaboration with Sarepta Therapeutics, Inc.

10 Feb 2015

ISG Health creates new algae-based nutraceutical products

International Sustainability Group, Inc. an innovative green technology company is pleased to announce that its wholly owned subsidiary ISG Health created its new algae based product line, being branded under the name AlgaeUP.

10 Feb 2015

Pfenex, Hospira sign agreement to develop and commercialize LUCENTIS biosimilar

Pfenex Inc., a clinical-stage biotechnology company engaged in the development of biosimilar therapeutics, and Hospira, Inc., the world's leading provider of injectable drugs and infusion technologies, and a global leader in biosimilars, today announced that the companies have entered into an agreement to exclusively develop and commercialize for worldwide sales PF582, Pfenex's biosimilar candidate to Genentech's LUCENTIS (ranibizumab injection).

10 Feb 2015

Too much folic acid during pregnancy puts daughters at risk of diabetes, obesity later in life

Mothers that take excessive amounts of folic acid during pregnancy may predispose their daughters to diabetes and obesity later in life, according to a new study published today in the Journal of Endocrinology. With high dose supplements being widely available, the study calls for a need to establish a safe upper limit of folic acid intake for pregnant women.

10 Feb 2015

Isis receives $5 million from Biogen Idec to develop drugs for neurological disorders

Isis Pharmaceuticals, Inc. announced today it has earned a $5 million milestone payment from Biogen Idec associated with the validation of an undisclosed target to treat a neurological disorder under its broad strategic collaboration with Biogen Idec to develop drugs to treat patients with neurological disorders.

10 Feb 2015

HPV vaccine does not increase rates of STIs in adolescent females

Receiving the human papillomavirus vaccine does not increase rates of sexually transmitted infections (STIs) in adolescent females. The vaccine, which can prevent cervical cancer in women, has had a low uptake, partly because of concerns about how it will affect adolescent sexual activity.

10 Feb 2015

Researchers identify axitinib as promising candidate to treat drug-resistant leukaemia

A study led by researchers at the Institute for Molecular Medicine Finland FIMM and Faculty of Medicine, University of Helsinki and the Helsinki University Central Hospital Comprehensive Cancer Center, in close collaboration with researchers at Pfizer, has identified a previously unrecognized action of Pfizer's axitinib as a potent inhibitor of the dominant mutation that confers drug resistance to all well tolerated treatments in patients with certain types of leukemia.

10 Feb 2015

Psychedelic drug prevents allergic asthma in mouse model

Research led by Charles Nichols, PhD, Associate Professor of Pharmacology and Experimental Therapeutics at the LSU Health New Orleans School of Medicine, has found that a psychedelic drug, (R)-DOI, prevents the development of allergic asthma in a mouse model.

10 Feb 2015

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

University of Chicago Medicine researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in ovarian cancer metastasis. Their three-dimensional cell-culture system, adapted for high-throughput screening, has enabled them to identify small molecules that can inhibit adhesion and invasion, preventing ovarian cancers from spreading to nearby tissues.

10 Feb 2015

Drug similar to Gleevec may help tame some brain cancers

The drug Gleevec (imatinib mesylate) is well known not only for its effectiveness against chronic myeloid leukemia (CML) and acute lymphoblastic leukemia, but also for the story behinds its development. The drug was specifically designed to target an abnormal molecule--a fusion of two normal cell proteins--that fueled a tumor's growth.

10 Feb 2015

Mice genetically deficient in serotonin are more vulnerable to social stressors

Mice genetically deficient in serotonin -- a crucial brain chemical implicated in clinical depression -- are more vulnerable than their normal littermates to social stressors, according to a Duke study appearing this week in the Proceedings of the National Academy of Sciences.

10 Feb 2015

Pharmaceutical News

Cumberland initiates clinical development of Boxaban (ifetroban) oral capsule for AERD treatment

ADDF, Pfizer's CTI collaborate to advance development of new drugs for Alzheimer's disease

Carma Laboratories' NEW Carmex Cold Sore Treatment named 2015 'Product of the Year' winner

Oncolytics' REOLYSIN receives FDA Orphan Drug Designation for treatment of ovarian cancer

ATA recommends daily serving of iodine in multivitamin/mineral supplements for pregnant, breastfeeding women

Researchers close to novel therapy to treat levodopa-induced dyskinesia

OSU researchers discover impact of antibiotics on microorganisms that live in animal's gut

Study shows low-dose oral iron supplementation after blood donation reduces hemoglobin recovery time

Researchers suggest significant relationship between cannabis use and mania symptoms

Experimental Ebola virus medication shows promise in monkeys

ISG Health creates new algae-based nutraceutical products

Pfenex, Hospira sign agreement to develop and commercialize LUCENTIS biosimilar

Too much folic acid during pregnancy puts daughters at risk of diabetes, obesity later in life

Isis receives $5 million from Biogen Idec to develop drugs for neurological disorders

HPV vaccine does not increase rates of STIs in adolescent females

Researchers identify axitinib as promising candidate to treat drug-resistant leukaemia

Psychedelic drug prevents allergic asthma in mouse model

Study describes novel screening system that has potential to uncover effective ovarian cancer drugs

Drug similar to Gleevec may help tame some brain cancers

Mice genetically deficient in serotonin are more vulnerable to social stressors

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