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Study shows how anesthesia affects cells in central nervous system

Anesthesia, long considered a blessing to patients and surgeons, has been a mystery for much of its 160-plus-year history in the operating room.

14 Nov 2014

Alzheimer's drug may reduce addictive and impulsive behavior associated with binge eating

The Alzheimer's drug memantine may perform double-duty helping binge eaters control their compulsion.

14 Nov 2014

Laurus Labs to use Novasep Varicol continuous chromatography system

Novasep, a leading supplier of manufacturing solutions to the life sciences industry, and its long-time partner Nilsan Nishotech Systems, a specialist in process engineering in India, today announce the commissioning of a continuous chromatography Varicol system at Laurus Labs, one of India’s fastest growing API (Active Pharmaceutical Ingredients) makers.

14 Nov 2014

Representatives from 40 countries meet to discuss plan for antimicrobial resistance

Every year, 25,000 people die as a result of antimicrobial resistance in Europe. A global action plan against one of the greatest health threats of our time is the aim of a conference being held in Oslo on 13th-14th November.

14 Nov 2014

Vitamin B12, folic acid supplements may not reduce risk of memory and thinking problems

Taking vitamin B12 and folic acid supplements may not reduce the risk of memory and thinking problems after all, according to a new study published in the November 12, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology. The study is one of the largest to date to test long-term use of supplements and thinking and memory skills.

13 Nov 2014

Studies evaluate traditional management of heart attack patients after discharge from hospital

Beta-blockers have been a cornerstone in the treatment of heart attack survivors for more than a quarter of a century. However, many of the data predate contemporary medical therapy such as reperfusion, statins, and antiplatelet agents, and recent data have called the role of beta-blockers into question.

12 Nov 2014

Prescription opioids involved in 67.8% of nationwide ED visits in 2010, find researchers

Researchers from Rhode Island and The Miriam hospitals and the Stanford University School of Medicine have found that prescription opioids, including methadone, were involved in 67.8 percent of (or over 135,971 visits to) nationwide emergency department (ED) visits in 2010, with the highest proportion of opioid overdoses occurring in the South.

12 Nov 2014

Tdap vaccination during pregnancy not associated with increased risk of preterm delivery

Among approximately 26,000 women, receipt of the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine during pregnancy was not associated with increased risk of preterm delivery or small-for-gestational-age birth or with hypertensive disorders of pregnancy, although a small increased risk of being diagnosed with chorioamnionitis (an inflammation of the membranes that surround the fetus) was observed, according to a study in the November 12 issue of JAMA.

12 Nov 2014

Study reports anti-cancer activity in mice treated with experimental drug TAK-733

A University of Colorado Cancer Center study published online this week in the journal Molecular Cancer Therapeutics reports anti-cancer activity in 10 out of 11 patient tumor samples grown in mice and treated with the experimental drug TAK-733, a small molecule inhibitor of MEK1/2.

12 Nov 2014

High-absorption BCM-95 Curcumin can reduce spread of cancer cells

A recently published cellular study on colorectal cancer showed that high-absorption BCM-95 Curcumin is able to reduce the spread of cancer cells and potentially increase the effectiveness of chemotherapy in the treatment of advanced colon cancer.

11 Nov 2014

FDA accepts Amgen's evolocumab BLA for review

Amgen today announced that the U.S. Food and Drug Administration has accepted for review Amgen's Biologics License Application (BLA) for evolocumab for the treatment of high cholesterol.

11 Nov 2014

Sulindac drug can protect against oxidative damage due to AMD

While oxygen is essential to our planet's life force and the way we function and stay healthy, high concentrations referred to as oxidative stress may very well be the cause of more than 70 widely-spread diseases such as cancer, heart disease, neurodegenerative diseases, and eye diseases including macular degeneration.

11 Nov 2014

Two new oral medications post-transplant is safe, beneficial for patients with hepatitis C

All patients with hepatitis C who receive a liver transplant will eventually infect their new livers. These transplanted organs then require anti-viral treatment before they become severely damaged. But traditional post-transplant hepatitis C therapy can take up to a year, is potentially toxic and can lead to organ rejection.

11 Nov 2014

New drug combination shows promise as effective, safe treatment for rheumatoid arthritis

A new drug combination for rheumatoid arthritis treats the disease just as well as other intensive treatment strategies but with less medication and fewer side effects at a significantly lower cost. Doctoral researcher Diederik De Cock (KU Leuven) describes the strategy in a new study published in Annals of Rheumatic Diseases.

11 Nov 2014

Eribulin drug has minor added benefit in one patient group, indication of lesser benefit in others

Eribulin (trade name: Halaven) is approved for women with locally advanced or metastatic breast cancer in whom the disease has progressed despite prior drug therapy. The German Institute for Quality and Efficiency in Health Care (IQWiG) examined in a dossier assessment whether the drug offers an added benefit over the appropriate comparator therapy in these patient groups.

7 Nov 2014

Health benefits of modified formulation of curcumin supplements

The health benefits of over-the-counter curcumin supplements might not get past your gut, but new research shows that a modified formulation of the spice releases its anti-inflammatory goodness throughout the body.

7 Nov 2014

Zinc supplements more beneficial for some people with diabetes

Researchers at the Johns Hopkins University School of Medicine and elsewhere have found that genetic differences may account for why zinc supplements are more beneficial to some people than to others for the prevention and control of diabetes. The results of their pilot study of a population of Old Order Amish is believed to be the first to point out the relevance of small genetic differences in response to zinc supplementation at play in diabetes management.

7 Nov 2014

Osteoporosis drugs may also benefit patients with tumours outside the skeleton

Australian researchers have shown why calcium-binding drugs commonly used to treat people with osteoporosis, or with late-stage cancers that have spread to bone, may also benefit patients with tumours outside the skeleton, including breast cancer.

6 Nov 2014

MMRF initiative aims to speed up evaluation of new investigational drugs for multiple myeloma

The Multiple Myeloma Research Foundation today announced an initiative designed to accelerate the evaluation of new investigational therapies for multiple myeloma (MM).

6 Nov 2014

Isis receives $10 million from Biogen Idec to initiate IND-supporting studies of ISIS-BIIB3 Rx

Isis Pharmaceuticals, Inc. announced today that it has earned a $10 million milestone payment from Biogen Idec related to the initiation of investigational new drug (IND)-supporting studies of ISIS-BIIB3Rx. ISIS-BIIB3Rx is a recently identified development candidate designed to inhibit an undisclosed target to treat a neurodegenerative disease.

6 Nov 2014

Pharmaceutical News

Study shows how anesthesia affects cells in central nervous system

Alzheimer's drug may reduce addictive and impulsive behavior associated with binge eating

Laurus Labs to use Novasep Varicol continuous chromatography system

Representatives from 40 countries meet to discuss plan for antimicrobial resistance

Vitamin B12, folic acid supplements may not reduce risk of memory and thinking problems

Studies evaluate traditional management of heart attack patients after discharge from hospital

Prescription opioids involved in 67.8% of nationwide ED visits in 2010, find researchers

Tdap vaccination during pregnancy not associated with increased risk of preterm delivery

Study reports anti-cancer activity in mice treated with experimental drug TAK-733

High-absorption BCM-95 Curcumin can reduce spread of cancer cells

FDA accepts Amgen's evolocumab BLA for review

Sulindac drug can protect against oxidative damage due to AMD

Two new oral medications post-transplant is safe, beneficial for patients with hepatitis C

New drug combination shows promise as effective, safe treatment for rheumatoid arthritis

Eribulin drug has minor added benefit in one patient group, indication of lesser benefit in others

Health benefits of modified formulation of curcumin supplements

Zinc supplements more beneficial for some people with diabetes

Osteoporosis drugs may also benefit patients with tumours outside the skeleton

MMRF initiative aims to speed up evaluation of new investigational drugs for multiple myeloma

Isis receives $10 million from Biogen Idec to initiate IND-supporting studies of ISIS-BIIB3 Rx

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Digital pathology and the PathoVerse: A conversation with Dr. Singh

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