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Common genetic variation in gene may modify cardiovascular benefit of aspirin

Aspirin is the gold standard for antiplatelet therapy and a daily low-dose aspirin is widely prescribed for the prevention of cardiovascular disease.

21 Jul 2014

Study confirms link between antipsychotic medication and slight decrease in brain volume

A study published today has confirmed a link between antipsychotic medication and a slight, but measureable, decrease in brain volume in patients with schizophrenia.

19 Jul 2014

National Med Care partners with Taking You Forward for marketing pharmaceutical products in the U.S.

Richmond Private Equity Group Limited announced today that its "portfolio company", National Med Care Ltd, a Salt Lake City Utah, based pharmaceutical marketing firm has entered into an agreement with Taking You Forward Inc., a Cebu Philippines based BPO firm to form a joint venture for the marketing of its compound pharmaceutical products in the United States.

18 Jul 2014

Phase II study reveals potential biomarker for HIV vaccine

Further analysis of a Phase II study of therapeutic HIV vaccine candidate Vacc-4x revealed a potential biomarker associated with participants who experienced a more profound viral load reduction after receiving the vaccine.

18 Jul 2014

FDA approves Ruconest for treatment of acute attacks in adolescent patients with HAE

The U.S. Food and Drug Administration yesterday approved Ruconest, the first recombinant C1-Esterase Inhibitor product for the treatment of acute attacks in adult and adolescent patients with hereditary angioedema (HAE).

18 Jul 2014

Splice-switching oligonucleotide drugs alter editing of gene transcript

In splice-switching, an innovative therapeutic approach, targeted oligonucleotide drugs alter the editing of a gene transcript to produce the desired form of a protein.

18 Jul 2014

Asthma inhalers may suppress children's growth

Corticosteroid drugs that are given by inhalers to children with asthma may suppress their growth, evidence suggests. Two new systematic reviews published in The Cochrane Library focus on the effects of inhaled corticosteroid drugs (ICS) on growth rates.

17 Jul 2014

New study finds highest rates of decline in prescription drug misuse nationwide

Five states that have implemented multi-faceted prescription drug abuse prevention programs in recent years showed the highest rate of decline in prescription drug misuse rates nationwide, according to a new study issued today by Quest Diagnostics, the world's leading provider of diagnostic information services.

From Quest Diagnostics 17 Jul 2014

Ruthigen treats first human subjects with leading drug candidate RUT58-60

Ruthigen, Inc., today announced that it has treated the first human subjects with its leading drug candidate RUT58-60 in a 30 patient, 21-day skin irritation trial, which is expected to be completed in August 2014.

17 Jul 2014

Phase 2 dose-ranging study of AYX1 for prevention of post-surgical pain

Adynxx, developer of a first-in-class platform of therapeutics to address pain at its molecular roots, announced today that the first patient was dosed in ADYX-003, a Phase 2 dose-ranging study of AYX1, an investigational drug candidate for the prevention of post-surgical pain.

17 Jul 2014

FDA designated Astellas’ isavuconazole as QIDP for treatment of invasive candidiasis

Astellas today announced that the U.S. Food and Drug Administration (FDA) designated isavuconazole as a Qualified Infectious Disease Product (QIDP) for the treatment of invasive candidiasis, a life-threatening, invasive fungal infection.

17 Jul 2014

First publication describing use of CytoSorb during cardiac surgery

CytoSorbents Corporation, a critical care immunotherapy company commercializing its CytoSorb® cytokine adsorber in multiple countries worldwide, announced the PDF availability of the first publication describing the use of CytoSorb® intra-operatively during cardiac surgery at the Ludwig Maximilian University of Munich Hospital - Grosshadern Campus, in Germany.

17 Jul 2014

FDA grants Breakthrough Therapy designation to Boehringer Ingelheim’s nintedanib

Boehringer Ingelheim Pharmaceuticals, Inc. today announced that the U.S. Food & Drug Administration (FDA) has granted Breakthrough Therapy designation to nintedanib, an investigational therapy currently under FDA review for the treatment of people with idiopathic pulmonary fibrosis (IPF).

17 Jul 2014

New analysis provides information about which medications best after different types of surgery

Current guidelines do not distinguish between aspirin and more potent blood thinners for protecting against blood clots in patients who undergo major orthopedic operations, leaving the decision up to individual clinicians.

17 Jul 2014

Once-a-day pill for patients experiencing opioid-induced constipation

Opioids - strong morphine-based painkillers - are widely prescribed to patients experiencing chronic severe pain. While these drugs are very effective for treating and managing pain, they have one particularly bothersome side effect: constipation.

17 Jul 2014

GSK begins shipment of flu vaccines to U.S. for the upcoming 2014-15 season

GSK announced today it has begun shipping FLUARIX QUADRIVALENT (Influenza Vaccine) doses to U.S. healthcare providers. This is the first shipment of GSK’s U.S. flu vaccine supply for the flu season, following licensing and lot-release approval from the U.S. Food and Drug Administration’s Center for Biologics Evaluation and Research.

17 Jul 2014

Cholesterol-lowering statins may prolong lives of people with diabetic cardiovascular disease

Heart disease and stroke are the leading causes of death and disability among people with Type 2 diabetes. In fact, at least 65 percent of people with diabetes die from some form of heart disease or stroke, according to the American Heart Association.

17 Jul 2014

Researchers develop world's first T-cell peptide-based vaccine for heart disease

Researchers at Wayne State University have made a fundamental discovery and, in subsequent collaboration with scientists at La Jolla Institute for Allergy and Immunology (LIAI), are one step closer to the goal of developing the world's first T-cell peptide-based vaccine for heart disease - the number one killer in the nation.

17 Jul 2014

Prevalence of potentially inappropriate prescribing and prescribing omissions in older adults examined by new study from RCSI

A new study from RCSI (Royal College of Surgeons in Ireland) and Trinity College Dublin, which examined the prevalence of potentially inappropriate prescribing (PIP) and prescribing omissions in older Irish adults, has found that 14% of people over the age of 65 has been prescribed at least one inappropriate form of medication in their lives and 30% have not been prescribed clinically indicated medications, at least once in their lives. The

16 Jul 2014

Drug paraphernalia triggers reward areas of brain differently in marijuana users

New research from The University of Texas at Dallas demonstrates that drug paraphernalia triggers the reward areas of the brain differently in dependent and non-dependent marijuana users.

16 Jul 2014

Pharmaceutical News

Common genetic variation in gene may modify cardiovascular benefit of aspirin

Study confirms link between antipsychotic medication and slight decrease in brain volume

National Med Care partners with Taking You Forward for marketing pharmaceutical products in the U.S.

Phase II study reveals potential biomarker for HIV vaccine

FDA approves Ruconest for treatment of acute attacks in adolescent patients with HAE

Splice-switching oligonucleotide drugs alter editing of gene transcript

Asthma inhalers may suppress children's growth

New study finds highest rates of decline in prescription drug misuse nationwide

Ruthigen treats first human subjects with leading drug candidate RUT58-60

Phase 2 dose-ranging study of AYX1 for prevention of post-surgical pain

FDA designated Astellas’ isavuconazole as QIDP for treatment of invasive candidiasis

First publication describing use of CytoSorb during cardiac surgery

FDA grants Breakthrough Therapy designation to Boehringer Ingelheim’s nintedanib

New analysis provides information about which medications best after different types of surgery

Once-a-day pill for patients experiencing opioid-induced constipation

GSK begins shipment of flu vaccines to U.S. for the upcoming 2014-15 season

Cholesterol-lowering statins may prolong lives of people with diabetic cardiovascular disease

Researchers develop world's first T-cell peptide-based vaccine for heart disease

Prevalence of potentially inappropriate prescribing and prescribing omissions in older adults examined by new study from RCSI

Drug paraphernalia triggers reward areas of brain differently in marijuana users

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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