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Alnylam advances Development Candidate for ALN-AS1 for treatment of hepatic porphyrias

Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, announced today that it is advancing its Development Candidate for ALN-AS1, an RNAi therapeutic targeting aminolevulinate synthase-1 (ALAS-1) for the treatment of hepatic porphyrias including acute intermittent porphyria (AIP).

9 Oct 2013

Forma Achieves First Milestone In Celgene Collaboration

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8 Oct 2013

Study aims for new national standard on how doctors and pharmacies write prescriptions

Northwestern Medicine-, Walgreens, Alliance of Chicago community health centers and Merck are collaborating on a study with a deceptively simple goal: provide clear instructions on prescription medicine labels so patients don't make mistakes and overcomplicate taking their daily medications.

8 Oct 2013

Researchers re-invented class of popular antimicrobial drugs by altering their chemical structures

By tinkering with their chemical structures, researchers at the University of California, San Diego School of Medicine have essentially re-invented a class of popular antimicrobial drugs, restoring and in some cases, expanding or improving, their effectiveness against drug-resistant pathogens in animal models.

8 Oct 2013

Drug companies paid to attend FDA advisory panel meeting on painkillers' safety and effectiveness

A scientific panel that shaped the federal government's policy for testing the safety and effectiveness of painkillers was funded by major pharmaceutical companies that paid hundreds of thousands of dollars for the chance to affect the thinking of the Food and Drug Administration, according to hundreds of e-mails obtained by a public records request.

8 Oct 2013

Vaccination campaign led HBV to more than double rate of "breakout" mutations

A universal infant vaccination campaign in China has led the Hepatitis B virus (HBV) to more than double its rate of "breakout" mutations. These mutations may enable the virus to elude the vaccine, necessitating new vaccination strategies.

8 Oct 2013

New medications may be used to treat common heart-rhythm problem

An international research team led by medical scientists at the University of Alberta has shown that new medications based on resveratrol - a compound found in red wine and nuts - may be used to treat a common heart-rhythm problem known as atrial fibrillation.

8 Oct 2013

Tel Aviv University researchers find chemicals in marijuana could help treat MS

Multiple sclerosis is an inflammatory disease in which the immune system attacks the nervous system. The result can be a wide range of debilitating motor, physical, and mental problems. No one knows why people get the disease or how to treat it.

8 Oct 2013

Researchers examine probiotics to prevent excessive crying in infants

There still appears to be insufficient evidence to support using probiotics (Lactobacillus reuteri) to manage colic or to prevent crying in infants, especially in formula-fed babies, but it may be an effective treatment for crying infants who are breastfed exclusively and have colic, according to a study by Valerie Sung, M.P.H., of the Murdoch Childrens Research Institute and Royal Children's Hospital, Australia, and colleagues.

8 Oct 2013

Scientists devised technique to make antibody-drug conjugates, basis of new therapies

Chemists at The Scripps Research Institute (TSRI) have devised a new technique for connecting drug molecules to antibodies to make advanced therapies.

8 Oct 2013

Immutep, Eddingpharm partner to develop and commercialize ImmuFact IMP321

Immutep S.A., the biopharmaceutical company specializing in immuno-oncology, and Eddingpharm have entered into an agreement regarding the development, commercialization and manufacturing of Immutep’s ImmuFact IMP321.

7 Oct 2013

A*STAR, Debiopharm Team Up To Develop Epigenetic Cancer Target

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7 Oct 2013

GSK Adds Another Program To Isis Antisense Collab

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7 Oct 2013

Experimental Therapeutics, Debiopharm join to develop oral small molecules targeting new class of epigenetic modulators

The Agency for Science, Technology and Research (A*STAR)'s Experimental Therapeutics Centre (ETC), a center of excellence to advance and accelerate drug discovery in Singapore, and Debiopharm Group™ (Debiopharm), the Swiss-based global biopharmaceutical company that focuses on the development of prescription drugs that target unmet medical needs including oncology as well as companion diagnostics, today announced the signature of an exclusive research collaboration to develop oral small molecules targeting new class of epigenetic modulators.

7 Oct 2013

Newly discovered compound could be developed as antifungal drug to treat fungal infections

On a molecular level, you have more in common with shower curtain mold or the mushrooms on your pizza than you might think. Humans and fungi share similar proteins, a biological bond that makes curing fungal infections difficult and expensive.

7 Oct 2013

ERK pathway discovery may provide therapeutic options for treating drug addictions

The extracellular-signal regulated kinase (ERK) pathway plays a role in multiple drug addictions and appears to modulate neuronal plasticity through epigenetic mechanisms, say French scientists.

7 Oct 2013

Glutamergic agents may be used as novel treatment for mood and anxiety disorders

Glutamergic agents may one day be used as a novel treatment for mood and anxiety disorders, new research presented at the 26th ECNP Congress suggests.

7 Oct 2013

Self-medication is key reason for prescription drug abuse in docs

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5 Oct 2013

FDA approves Clinolipid injectable emulsion for intravenous feeding in adult patients

The U.S. Food and Drug Administration today approved Clinolipid (lipid injectable emulsion, USP) for intravenous feeding (parenteral nutrition) in adult patients, providing a source of calories and essential fatty acids for adult patients who are unable to eat or drink. Clinolipid was granted a priority review to help alleviate a drug shortage.

5 Oct 2013

Study shows precision medicine provides better treatment options for mentally ill person

A multidisciplinary team led by a geneticist and psychiatrist from Cold Spring Harbor Laboratory's (CSHL) Stanley Institute for Cognitive Genomics today publish a paper providing a glimpse of both the tremendous power and the current limitations of what is sometimes called "precision medicine."

5 Oct 2013

Pharmaceutical News

Alnylam advances Development Candidate for ALN-AS1 for treatment of hepatic porphyrias

Forma Achieves First Milestone In Celgene Collaboration

Study aims for new national standard on how doctors and pharmacies write prescriptions

Researchers re-invented class of popular antimicrobial drugs by altering their chemical structures

Drug companies paid to attend FDA advisory panel meeting on painkillers' safety and effectiveness

Vaccination campaign led HBV to more than double rate of "breakout" mutations

New medications may be used to treat common heart-rhythm problem

Tel Aviv University researchers find chemicals in marijuana could help treat MS

Researchers examine probiotics to prevent excessive crying in infants

Scientists devised technique to make antibody-drug conjugates, basis of new therapies

Immutep, Eddingpharm partner to develop and commercialize ImmuFact IMP321

A*STAR, Debiopharm Team Up To Develop Epigenetic Cancer Target

GSK Adds Another Program To Isis Antisense Collab

Experimental Therapeutics, Debiopharm join to develop oral small molecules targeting new class of epigenetic modulators

Newly discovered compound could be developed as antifungal drug to treat fungal infections

ERK pathway discovery may provide therapeutic options for treating drug addictions

Glutamergic agents may be used as novel treatment for mood and anxiety disorders

Self-medication is key reason for prescription drug abuse in docs

FDA approves Clinolipid injectable emulsion for intravenous feeding in adult patients

Study shows precision medicine provides better treatment options for mentally ill person

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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