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Understanding the mechanisms behind rising antifungal drug resistance

In a recent study, researchers addressed the issue of the rise of antifungal drugs-resistant infections and the advent of multidrug-resistant fungal pathogens.

19 Jul 2023

Opioids linked to increased risk of death in older adults with dementia

The study population included everyone in Denmark aged 65 and older diagnosed with dementia between Jan. 1, 2008 and Dec. 31, 2018 (n=75,471), including both home-living and nursing home residents. Of that group, 42% (31,619) of those diagnosed with dementia redeemed a prescription for an opioid at a pharmacy.

18 Jul 2023

AI model accurately predicts which drugs may cause birth defects

Data scientists at the Icahn School of Medicine at Mount Sinai in New York and colleagues have created an artificial intelligence model that may more accurately predict which existing medicines, not currently classified as harmful, may in fact lead to congenital disabilities.

17 Jul 2023

Berkeley Lab and Genentech collaborate to develop new lipid nanoparticles for drug delivery

Many diseases can be successfully treated in the simple environment of a cell culture dish, but to successfully treat real people, the drug agent has to take a journey through the infinitely more complex environment within our bodies and arrive, intact, inside the affected cells.

17 Jul 2023

Exploring the efficacy of topical lidocaine in individuals with chronic neck pain

A team of researchers investigated the efficacy of lidocaine for the treatment of neck pain.

17 Jul 2023

MGI empowers life cienss industry with revolutionary what if campaign at XXIIIrd International Congress of Genetics

MGI Tech Co. Ltd. (MGI), a company committed to building core tools and technology to lead life science, today announced the launch of a global brand campaign titled “What If?” at the XXIII International Congress of Genetics (ICG), a five-yearly conference to bring together the international genetics community from around the world.

From MGI 17 Jul 2023

NIH funding for phased clinical trials represents <3.5% of total spending

The U.S. National Institutes of Health (NIH) contributed $8.1 billion in project funding for phased clinical trials involving drugs approved by the FDA from 2010-2019, according to a new study from Bentley University's Center for Integration of Science and Industry.

14 Jul 2023

C-Path and Vivpro join forces to advance drug development

Critical Path Institute, a leading global nonprofit committed to expediting drug development through the acceleration of regulatory-endorsed solutions, today announced a newly formalized Memorandum of Understanding with Vivpro, an industry-leading provider of a revolutionary biointelligence software platform and innovative services.

13 Jul 2023

Pharmacist-led intervention can help suppress multi-drug resistant pathogens

The battle to stop the increase of superbugs in hospitals has been an ongoing struggle for healthcare professionals.

13 Jul 2023

Wait, What’s a PBM?

Pharmacy benefit managers, or PBMs, are intermediary companies that negotiate the price of prescription drugs.

13 Jul 2023

Lecanemab: First disease-modifying therapy for Alzheimer's disease approved by FDA

On July 6, 2023, the U.S. Food and Drug Administration granted full approval to lecanemab, marketed as Leqembi, for the treatment of Alzheimer's disease.

12 Jul 2023

Older age and certain health conditions increase risk of COVID-19 death in boosted individuals

Researchers identify patient groups at a higher risk of death due to COVID-19 among adults who received a second booster dose in England.

12 Jul 2023

Rethinking how cancer immunotherapy drugs are delivered could save millions

A new analysis finds that up to millions of dollars could be saved annually on cancer immunotherapy treatments across the Veterans Health Administration by reconsidering how those drugs are delivered.

11 Jul 2023

THC-O-acetate's psychedelic effects may be greatly exaggerated

The cannabis plant is complex, with about 100 cannabinoids, or compounds, many of which science still knows little or nothing about.

11 Jul 2023

Gift of $1.5 million will fund DMT research at UC San Diego

One of the most powerful psychedelics known, N,N-dimethyltryptamine (DMT) has been described as causing imaginative visuals akin to the dream state.

11 Jul 2023

Prescription stimulants safe for treating ADHD, study finds

Many parents whose kids take prescription stimulants like Ritalin to treat ADHD worry that it could lead to illicit drug use later.

11 Jul 2023

Novel vaccine against Lyme disease reported to be safe and effective

Researchers determine the safety and immunogenicity of a novel candidate vaccine against Lyme borreliosis.

11 Jul 2023

The American Journal of Health Economics articles examine policies to address opioid crisis

The August 2023 issue of the American Journal of Health Economics will feature a cluster of articles that examine the opioid crisis.

10 Jul 2023

New drug shows synergistic effect with antifungals in killing drug-resistant fungi

A study conducted at the University of São Paulo (USP) in Brazil shows that brilacidin, a new drug tested for treatment of diseases ranging from bacterial skin infections to COVID-19, can kill drug-resistant strains of fungi when combined with two classes of antifungals available on the market.

10 Jul 2023

AMP releases consensus recommendations for CYP3A4 and CYP3A5 genotyping assays

The Association for Molecular Pathology (AMP), the premier global molecular diagnostic professional society, today published consensus recommendations to aid in the design and validation of clinical CYP3A4 and CYP3A5 genotyping assays, promote standardization of testing across different laboratories, and improve patient care.

10 Jul 2023