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Study: Prescribing rate of non-opioid pain medications increased after 2016 CDC guideline

After the Centers for Disease Control and Prevention released a guideline for prescribing opioids to patients experiencing chronic pain in 2016, the prescribing rate of non-opioid pain medication increased each year above and beyond what would be expected based on the preexisting trends, a new study finds.

15 Jul 2022

As Big Pharma loses interest in new antibiotics, infections are only growing stronger

Forget covid-19, monkeypox, and other viruses for the moment and consider another threat troubling infectious disease specialists: common urinary tract infections, or UTIs, that lead to emergency room visits and even hospitalizations because of the failure of oral antibiotics.

15 Jul 2022

Sore throat lozenges and sprays provide only a small reduction in throat pain

It's hard to get through a winter without suffering sore throat, but luckily they normally get better within a few days.

15 Jul 2022

Prescribing lower quantities of opioids may effectively control postoperative pain after knee surgery

Prescribing smaller quantities of opioid medication appears to be as effective in controlling postoperative pain after knee surgery as higher quantities and may help to limit the number of opioids prescribed and possible diversion of unused prescription opioid medication, according to research presented today at the American Orthopaedic Society of Sports Medicine 2022 Annual Meeting

15 Jul 2022

Long-established drug for angina pectoris shows anti-inflammatory effect, reduces atherosclerotic plaques

A drug used in the clinical treatment of angina symptoms also has an anti-inflammatory effect and reduces atherosclerotic plaques in blood vessels - thereby reducing the risk of heart attack or stroke.

14 Jul 2022

Availability of lower-priced epinephrine auto-injectors did not solve the affordability problem for all patients with severe allergies

People with severe allergies now have more choices for which epinephrine auto-injector to carry in case they suffer a life-threatening attack, and most pay less for it than they did when the EpiPen was the primary option, a new study shows.

12 Jul 2022

Commonly prescribed class of migraine drugs may be effective in treating obesity

Triptans, a commonly prescribed class of migraine drugs, may also be useful in treating obesity, a new study by scientists at UT Southwestern suggests.

11 Jul 2022

Nanoparticle vaccine could protect against animal viruses including future SARS-CoV-2 variants

A recent study published in the Science journal depicted that mosaic receptor-binding domain (RBD) nanoparticles immunize from diverse sarbecovirus challenges, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), among animal models.

8 Jul 2022

Discovery of multiple new SARS-CoV-2 MPro inhibitors

In a recent study posted to the bioRxiv* preprint server, researchers performed an extensive library docking for new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) covalent and non-covalent inhibitors.

8 Jul 2022

Chicoric acid a potential candidate for COVID-19 treatment

An article under review in the Scientific Reports journal and currently available on the Research Square* preprint server reports on chicoric acid (CA) as a potential inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Jul 2022

Noradrenergic drugs could be repurposed to offer effective treatment for Alzheimer's disease symptoms

There is "good evidence" that drugs to treat attention deficit hyperactivity disorder (ADHD) might also successfully treat key aspects of Alzheimer's disease, finds a pooled data analysis of the available research, published online in the Journal of Neurology Neurosurgery & Psychiatry.

6 Jul 2022

Study reports how opioids cause gastric inflammation

Opioids are the gold standard for treatment of chronic and acute pain; however, their use may result in significant gastrointestinal side effects, including nausea, vomiting, and constipation.

6 Jul 2022

Research highlights importance of designing effective COVID vaccine allocation strategies

In a recent study posted to the medRxiv* pre-print server, researchers at the University of Melbourne used a modified Susceptible, Exposed, Infectious, and Recovered (SEIR) mathematical model to examine the impact of different vaccine mechanisms and disease characteristics on a population comprised of individuals at high and low risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

6 Jul 2022

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

In a recent study published in the bioRxiv* preprint server, researchers at the Medical University of Innsbruck assessed the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3CLpro mutations responsible for Paxlovid resistance. The 3-chymotrypsin-like protease (3CLPro), or main protease (Mpro), is the main protease found in coronaviruses.

6 Jul 2022

Novel inhalable COVID-19 vaccine

A recent study published in the Nature Biomedical Engineering journal illustrated a novel inhalable SARS-CoV-2 vaccine candidate centered on exosomes (Exos) coupled with recombinant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain (RBD).

5 Jul 2022

How Pfizer won the pandemic, reaping outsize profit and influence

The grinding two-plus years of the pandemic have yielded outsize benefits for one company — Pfizer — making it both highly influential and hugely profitable as covid-19 continues to infect tens of thousands of people and kill hundreds each day.

5 Jul 2022

Patient-derived antibody cocktail active across SARS-CoV-2 variants of concern

In a recent study published in the journal Science Immunology, researchers in the United States described a rare anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) three antibody cocktail IMM-BCP-01.

4 Jul 2022

West Health issues statement on reports that Senate Democrats will lower prescription drug prices through reconciliation bill

West Health Chief Executive Officer Shelley Lyford issued the following statement on reports that Senate Democrats have reached agreement to move forward on a reconciliation bill that includes major provisions to lower prescription drug prices.

2 Jul 2022

SARS-CoV-2 can evade Paxlovid by multiple mechanisms

In a recent article posted to the bioRxiv* preprint server, researchers at Rutgers, the State University of New Jersey, the University of South Florida, and the Catholic University of America demonstrated that the natural severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) mutations result in nirmatrelvir resistance.

30 Jun 2022

Mosaic-8 RBD-nanoparticles show promise against current and future SARS-CoV-2 variants

A recent study posted to the bioRxiv* preprint server supports using mosaic sarbecovirus receptor-binding domain (RBD)-nanoparticles to discover therapeutic pan-variant and pan-sarbecovirus monoclonal antibodies (mAbs) and to induce mAbs by vaccination.

30 Jun 2022

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Pharmaceutical News

Study: Prescribing rate of non-opioid pain medications increased after 2016 CDC guideline

As Big Pharma loses interest in new antibiotics, infections are only growing stronger

Sore throat lozenges and sprays provide only a small reduction in throat pain

Prescribing lower quantities of opioids may effectively control postoperative pain after knee surgery

Long-established drug for angina pectoris shows anti-inflammatory effect, reduces atherosclerotic plaques

Availability of lower-priced epinephrine auto-injectors did not solve the affordability problem for all patients with severe allergies

Commonly prescribed class of migraine drugs may be effective in treating obesity

Nanoparticle vaccine could protect against animal viruses including future SARS-CoV-2 variants

Discovery of multiple new SARS-CoV-2 MPro inhibitors

Chicoric acid a potential candidate for COVID-19 treatment

Noradrenergic drugs could be repurposed to offer effective treatment for Alzheimer's disease symptoms

Study reports how opioids cause gastric inflammation

Research highlights importance of designing effective COVID vaccine allocation strategies

Paxlovid resistance associated with SARS-CoV-2 3CLpro mutations

Novel inhalable COVID-19 vaccine

How Pfizer won the pandemic, reaping outsize profit and influence

Patient-derived antibody cocktail active across SARS-CoV-2 variants of concern

West Health issues statement on reports that Senate Democrats will lower prescription drug prices through reconciliation bill

SARS-CoV-2 can evade Paxlovid by multiple mechanisms

Mosaic-8 RBD-nanoparticles show promise against current and future SARS-CoV-2 variants

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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