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New blood test could predict women at higher risk of preeclampsia

The causes of preeclampsia, a multi-system disorder that affects women in pregnancy, have not been fully elucidated. The condition, which is typically associated with high blood pressure and an increased amount of protein in the urine, affects 2 to 5 percent of pregnant women, and is one of the main reasons for complications during the second half of pregnancy. Preeclampsia is frequently diagnosed too late and, in the most severe cases, can be fatal for both mother and child.

11 Jan 2016

U-M research could lead to new ways of fighting X-linked diseases in girls and women

Nearly every girl and woman on Earth carries two X chromosomes in nearly every one of her cells -- but one of them does (mostly) nothing. That's because it's been silenced, keeping most of its DNA locked up and unread like a book in a cage.

11 Jan 2016

Auranofin drug could improve prognosis for ovarian cancer patients exhibiting BRCA1 deficiency

An anti-rheumatic drug could improve the prognosis for ovarian cancer patients exhibiting a deficiency of the DNA repair protein BRCA1, a study suggests.

11 Jan 2016

Having more kids may lead to slower rate of aging

A study by Simon Fraser University researchers suggests that the number of children born to a woman influences the rate at which her body ages.

11 Jan 2016

SDPR gene may help to predict disease progression, serve as target for future breast cancer therapies

A gene that plays a role in the development of breast cancer to metastatic disease has been identified which may help to predict disease progression and serve as a target for the development of future breast cancer therapies.

11 Jan 2016

Roche’s Elecsys blood test could help predict pre-eclampsia in pregnant women

A new study published in the New England Journal of Medicine today shows that Roche’s Pre-eclampsia Elecsys® blood test can predict which pregnant women will, and will not, develop pre-eclampsia, one of the leading causes of death and complications for mothers and their unborn babies.

8 Jan 2016

Cancer mortality continues to drop in the U.S.

Steady reductions in smoking combined with advances in cancer prevention, early detection, and treatment have resulted in a 23% drop in the cancer death rate since its peak in 1991. The drop translates to more than 1.7 million cancer deaths averted through 2012.

8 Jan 2016

Pancreatic cancer to surpass breast cancer to become third leading cause of deaths in U.S.

Pancreatic cancer is expected to surpass breast cancer to become the third leading cause of cancer-related deaths in the United States, according to the latest Cancer Statistics 2016 report, published today by the American Cancer Society in CA: A Cancer Journal for Clinicians.

8 Jan 2016

Biocept introduces blood-based test for detection, monitoring of prostate cancer and breast cancer

Biocept, Inc., a molecular diagnostics company commercializing and developing biomarkers to improve the detection and treatment of cancer, announces the launch of the CLIA-validated androgen receptor expression assay using a patient's blood for the detection and monitoring of late-stage prostate cancer and a certain form of breast cancer.

7 Jan 2016

Penn study provides new insight into cause of peripartum cardiomyopathy in pregnant women

Each year approximately 1 in 1,000 pregnant women will experience peripartum cardiomyopathy, an uncommon form of often severe heart failure that occurs in the final month of pregnancy or up to five months following delivery. But the cause of peripartum cardiomyopathy has been largely unknown - until now.

7 Jan 2016

Promising novel approach to treat gynecologic tumors

UCLA scientists have developed a promising novel method to treat gynecologic tumors. The approach focuses on a protein called p53, which is commonly mutated in women who have high-grade serous ovarian cancer, the deadliest form of reproductive cancer. In many women with the disease, the cancer is very advanced by the time it is diagnosed and is therefore difficult to treat.

7 Jan 2016

Scientists find genetic link to unexplained heart failure affecting pregnant women

Scientists have found that women who suffer unexplained heart failure towards the end of pregnancy or shortly after giving birth share certain genetic changes.

7 Jan 2016

Older age at menopause associated with lower depression risk

A review of medical literature suggests older age at menopause was associated with a lower risk of depression for women in later life. Eleni Th Petridou, M.D., M.P.H., Ph.D., of the National and Kapodistrian University of Athens, Greece, and coauthors included 14 studies in a meta-analysis that represented nearly 68,000 women.

7 Jan 2016

FAU study shows benefits of regular mammography among elder women

Breast cancer is the second most common cancer in women after skin cancer and occurred in 230,000 women in the United States in 2015. Breast cancer afflicts 1 in 8 women in their lifetime and 1 in 25 die from this disease.

7 Jan 2016

New study finds familial risk and heritability of cancer among twins

A large new study of twins has found that having a twin sibling diagnosed with cancer poses an excess risk for the other twin to develop any form of cancer. Among the 23 different types of cancer studied, an excess familial risk was seen for almost all of the cancers, including common cancers such as breast and prostate cancer, but also more rare cancers such as testicular cancer, head and neck cancer, melanoma, ovarian and stomach cancer.

6 Jan 2016

Study may hold new revelations about how stress during pregnancy affects mothers and offspring

The sequencing of the first genome involving a cockroach species may one day serve as a model system comparable to how research on mice can apply to humans. In this case, the model could hold new revelations about how stress during pregnancy could affect both the mother and her offspring.

6 Jan 2016

Use of oral fluconazole during pregnancy associated with increased risk of spontaneous abortion

In an analysis of approximately 1.4 million pregnancies in Denmark, use of the oral antifungal medication fluconazole during pregnancy was associated with an increased risk of spontaneous abortion compared with risk among unexposed women and women who used a topical antifungal during pregnancy, according to a study in the January 5 issue of JAMA.

6 Jan 2016

Researchers find no evidence that prenatal exposure to antidepressants increases risk for autism, ADHD

An analysis of medical records data from three Massachusetts health care systems finds no evidence that prenatal exposure to antidepressants increases the risk for autism and related disorders or for attention-deficit hyperactivity disorder (ADHD).

6 Jan 2016

Using antidepressant drug during first trimester of pregnancy may increase risk of birth defects

Using paroxetine--a medication prescribed to treat conditions including depression, obsessive-compulsive disorder, anxiety and posttraumatic stress disorder--during the first trimester of pregnancy may increase newborns' risk of congenital malformations and cardiac malformations. That's the conclusion of a recent analysis published in the British Journal of Clinical Pharmacology.

6 Jan 2016

Millendo signs license agreement, secures funding to test new drugs for treatment of endocrine disorders

Millendo Therapeutics, a University of Michigan startup company, announced an exclusive license agreement with AstraZeneca for the worldwide development and commercialization rights to test a new compound, MLE4901, for the treatment of polycystic ovary syndrome.

6 Jan 2016

Women's Health News

New blood test could predict women at higher risk of preeclampsia

U-M research could lead to new ways of fighting X-linked diseases in girls and women

Auranofin drug could improve prognosis for ovarian cancer patients exhibiting BRCA1 deficiency

Having more kids may lead to slower rate of aging

SDPR gene may help to predict disease progression, serve as target for future breast cancer therapies

Roche’s Elecsys blood test could help predict pre-eclampsia in pregnant women

Cancer mortality continues to drop in the U.S.

Pancreatic cancer to surpass breast cancer to become third leading cause of deaths in U.S.

Biocept introduces blood-based test for detection, monitoring of prostate cancer and breast cancer

Penn study provides new insight into cause of peripartum cardiomyopathy in pregnant women

Promising novel approach to treat gynecologic tumors

Scientists find genetic link to unexplained heart failure affecting pregnant women

Older age at menopause associated with lower depression risk

FAU study shows benefits of regular mammography among elder women

New study finds familial risk and heritability of cancer among twins

Study may hold new revelations about how stress during pregnancy affects mothers and offspring

Use of oral fluconazole during pregnancy associated with increased risk of spontaneous abortion

Researchers find no evidence that prenatal exposure to antidepressants increases risk for autism, ADHD

Using antidepressant drug during first trimester of pregnancy may increase risk of birth defects

Millendo signs license agreement, secures funding to test new drugs for treatment of endocrine disorders

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research

Todd Bauman and Chris Povich

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