Bladder Cancer

In North America, bladder cancer is the fourth most common cancer in men and in the top ten for women. In the United States, approximately 70,000 patients are newly diagnosed with bladder cancer each year.

What is Bladder Cancer?

Bladder cancer refers to the growth of a tumor within the lining of the bladder. In some cases, the tumor can invade surrounding tissue and spread to other parts of the body.

What Causes Bladder Cancer?

Bladder Cancer Diagnosis

Bladder Cancer Treatment

Bladder Cancer Types

Symptoms of Bladder Cancer

What is Intravesical Therapy?

Bladder Cancer Biomarkers

Bladder Cancer Histopathology

Endoscopic Imaging for Bladder Cancer

Thromboembolism in Bladder Cancer

Non-Invasive Diagnostic Strategies for Bladder Cancer

See more featured articles »

Bladder Cancer Genomics

Bladder Cancer Risk Factors

Muscle Invasive Bladder Cancer (MIBC)

Muscle Invasive Bladder Cancer (MIBC) Diagnosis and Treatment

Latest Bladder Cancer News and Research

Machine learning increases the accuracy of anti-cancer drug response predictions

With the advent of pharmacogenomics, machine learning research is well underway to predict the patients' drug response that varies by individual from the algorithms derived from previously collected data on drug responses.

2 Nov 2020

Phase II NRG Oncology trial evaluates two regimens for muscle-invasive bladder cancer

Bladder preservation with trimodality therapy can be a safe and effective alternative to cystectomy for selected patients with muscle-invasive bladder cancer.

27 Oct 2020

Scientists uncover a novel cellular mechanism for disposing of misfolded proteins

About 30 years ago, Dr. Richard Sifers set out on a journey to discover why people with a rare condition known as alpha1-antitrypsin deficiency present with high variation in the severity of liver disease.

21 Oct 2020

Neoadjuvant trial of combination immunotherapy has favorable outcomes in bladder cancer patients

Neoadjuvant, or pre-surgical, combination treatment with the immune checkpoint inhibitors tremelimumab (anti-CTLA-4) and durvalumab (anti-PD-1) was well-tolerated and showed early signs of activity in certain patients with localized bladder cancer who do not have standard treatment options available, according to a Phase I clinical trial conducted by The University of Texas MD Anderson Cancer Center.

13 Oct 2020

UroCAD assay is better than urine cytology in detecting bladder cancer

Analysis of DNA copy number variants (CNVs) in the cells exfoliated in urine showed better sensitivity and similar specificity in detecting urothelial carcinoma compared with urine cytology.

9 Oct 2020

Robotic surgery poses challenges as hospital resume elective surgery amid COVID-19

Robotic surgery plays a major role in modern management of prostate cancer, bladder cancer, and other conditions treated by urologists. But it also poses some special challenges as hospitals resume elective surgery amid the COVID-19 pandemic.

7 Oct 2020

Antibody improves progression-free survival in patients with advanced prostate cancer

An antibody for treating advanced prostate cancer improves progression-free survival in patients with metastasised, castration-resistant prostate cancer.

29 Sep 2020

Immunotherapy extends survival in patients with advanced bladder cancer

An immunotherapy drug called 'avelumab' has been shown to significantly improve survival in patients with the most common type of bladder cancer, according to results from a phase III clinical trial led by Queen Mary University of London and Barts Cancer Centre, UK.

18 Sep 2020

PPI use linked to worse outcomes in urothelial cancer patients treated with atezolizumab

Proton pump inhibitor (PPI) use was associated with worse outcomes in patients with urothelial cancer treated with the immunotherapeutic atezolizumab (Tecentriq), compared with patients who did not use PPIs.

17 Sep 2020

Tobacco smoking linked to worse outcomes for bladder cancer patients after surgery

Patients treated for bladder cancer with a surgery known as radical cystectomy have worse outcomes if they are smokers, according to a systematic review and meta-analysis by Keck Medicine of USC.

15 Sep 2020

Study: Cigarette smoking is linked to worse outcomes in patients treated for bladder cancer

Patients treated for bladder cancer with a surgery known as radical cystectomy have worse outcomes if they are smokers, according to a systematic review and meta-analysis by Keck Medicine of USC. The study appeared in The Journal of Urology.

14 Sep 2020

Six genomics research projects receive grants to address the role of ethnicity in major cancers

Leading cancer scientists working with the New York Genome Center (NYGC) announced today that grants are being awarded to fund six projects that address the role of ethnicity in several major cancer types, taking advantage of the diversity of patients being treated at health care institutions throughout the New York City area.

8 Sep 2020

Study explores link between personal use of hair dyes and cancer risk

Studies have indicated that people who dye their hair regularly may have a higher risk of cancer, especially bladder cancer and breast cancer.

3 Sep 2020

Study identifies a novel regulatory pathway in bladder cancer

Researchers from Johns Hopkins University in collaboration with Insilico Medicine announce the publication of a new research paper titled "GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma" in Science Signaling.

20 Aug 2020

UIC's first-of-its-kind contraceptive receives FDA approval

A first-of-its-kind contraceptive developed at the University of Illinois Chicago has been approved by the U.S. Food and Drug Administration.

19 Aug 2020

Researchers discover how gut bacteria help the immune system to battle cancerous tumors

Researchers with the Snyder Institute for Chronic Diseases at the Cumming School of Medicine have discovered which gut bacteria help our immune system battle cancerous tumors and how they do it.

13 Aug 2020

Study sheds new light on mechanisms of cohesin function involved in cancer and cardiac development

Ana Losada, from the Spanish National Cancer Research Centre (CNIO), is the scientist who identified cohesin in vertebrates, a protein that is essential in cell division.

12 Aug 2020

Avoiding care during the pandemic could mean life or death

These days, Los Angeles acting teacher Deryn Warren balances her pain with her fear. She's a bladder cancer patient who broke her wrist in November. She still needs physical therapy for her wrist, and she's months late for a cancer follow-up.

31 Jul 2020

Non-invasive urine test being offered free to the NHS to help clear bladder cancer diagnoses backlog

A HIGHLY accurate urine test which can rule out bladder cancer with a negative-predictive value of 99% using a hospital laboratory’s standard ELISA testing equipment is today being offered free to the NHS to help urologists clear the backlog of people waiting for a diagnosis and monitoring as a result of COVID-19 hospital closures.

25 Jul 2020

New scanner to detect early signs of bladder cancer could save thousands of lives

Thousands of lives lost to bladder cancers each year could be saved thanks to a new scanner that uses photonics to illuminate parts of the tissue that are currently impossible to visualize.

3 Jul 2020