Bladder Cancer

In North America, bladder cancer is the fourth most common cancer in men and in the top ten for women. In the United States, approximately 70,000 patients are newly diagnosed with bladder cancer each year.

What is Bladder Cancer?

Bladder cancer refers to the growth of a tumor within the lining of the bladder. In some cases, the tumor can invade surrounding tissue and spread to other parts of the body.

What Causes Bladder Cancer?

Bladder Cancer Diagnosis

Bladder Cancer Treatment

Bladder Cancer Types

Symptoms of Bladder Cancer

What is Intravesical Therapy?

Bladder Cancer Biomarkers

Bladder Cancer Histopathology

Endoscopic Imaging for Bladder Cancer

Thromboembolism in Bladder Cancer

Non-Invasive Diagnostic Strategies for Bladder Cancer

See more featured articles »

Bladder Cancer Genomics

Bladder Cancer Risk Factors

Muscle Invasive Bladder Cancer (MIBC)

Muscle Invasive Bladder Cancer (MIBC) Diagnosis and Treatment

Latest Bladder Cancer News and Research

SWOG S1011 trial questions the benefits of extended lymphadenectomy in bladder cancer

The SWOG S1011 randomized phase 3 trial found no significant improvement in disease-free or overall survival but a higher rate of grade 3-4 adverse events and an increased risk of death in the 90 days after surgery.

3 Oct 2024

UTA cancer researcher elected president of the American Society for Photobiology

University of Texas at Arlington cancer researcher Sherri McFarland has been elected president of the American Society for Photobiology (ASP), a national scientific organization dedicated promoting research related to the effects of light on human health and the broader natural world.

20 Sep 2024

FORT-2 trial shows promising results for bladder cancer immunotherapy combination

Findings from the international FORT-2 clinical trial showed that a combination treatment including immunotherapy is safe and tolerable in patients with locally advanced or metastatic bladder cancer.

19 Sep 2024

Postsurgical treatment with pembrolizumab doubles cancer-free time for bladder cancer patients

Results from a large clinical trial show that treatment with an immunotherapy drug may nearly double the length of time people with high-risk, muscle-invasive bladder cancer are cancer-free following surgical removal of the bladder.

17 Sep 2024

Long-term benefits of immunotherapy highlighted in advanced melanoma and other cancers

Immunotherapy, which works by enabling the body's immune system to recognize and destroy cancer cells improves long-term overall survival in patients with advanced melanoma in results from large international studies reported at ESMO 2024.

16 Sep 2024

Family member’s cancer diagnosis may increase risks of psychological and cardiovascular illnesses

New research suggests that a family member’s cancer diagnosis may increase first-degree relatives’ and spouses’ risks of developing psychological and cardiovascular illnesses.

16 Sep 2024

UQ study unlocks potential for advanced bladder cancer immunotherapy

University of Queensland research could lead to a more effective immunotherapy treatment against bladder cancer.

27 Aug 2024

UQ research could lead to a more effective treatment for bladder cancer

University of Queensland research could lead to a more effective immunotherapy treatment against bladder cancer.

20 Aug 2024

UofL researchers receive $3.6 million to study the role of arsenic exposure in causing health problems

University of Louisville researchers have received $3.6 million in new grant funding to study the role of arsenic exposure in causing cancer and other major health concerns.

20 Aug 2024

New perspectives on targeting BRAF alterations in cancer

A new research perspective was published in Oncotarget's Volume 15 on July 16, 2024, entitled, "Targeting the multifaceted BRAF in cancer: New directions."

12 Aug 2024

New insights into the role of cancer-associated fibroblasts in promoting lymphatic metastasis

Lymph node metastasis is a crucial factor in cancer progression, significantly affecting patient prognosis and treatment outcomes.

8 Aug 2024

Zebrafish model reveals how BCG vaccine triggers immune response in bladder cancer

Using zebrafish "Avatars", an animal model developed by the Cancer Development and Innate Immune Evasion lab at the Champalimaud Foundation (CF), led by Rita Fior, Mayra Martínez-López – a former PhD student at the lab now working at the Universidad de las Américas in Quito, Ecuador – and colleagues studied the initial steps of the Bacillus Calmette-Guérin (BCG) vaccine's action on bladder cancer cells.

8 Aug 2024

METRNL protein identified as key player in cancer progression

A protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting their ability to fight cancer, according to new research directed by investigators at the Johns Hopkins University School of Medicine and the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. Finding ways to block the effects of METRNL signaling on tumor-infiltrating T cells may allow these immune cells to regain the energy necessary to eliminate tumors.

7 Aug 2024

Microbes play key role in carcinogenesis

At any given time, over 10 trillion microbes call our guts their home. From breaking down nutrients in our food to strengthening our immunity against pathogens, these microbes play an essential role in how we interact with the world. This includes – as shown in a new study by EMBL researchers and collaborators at the University of Split, Croatia – the way the body responds to carcinogens and develops cancer.

1 Aug 2024

DNA repair gene mutations predict bladder cancer response to neoadjuvant chemotherapy

An analysis of pre-treatment tumor specimens from 105 patients with localized muscle-invasive bladder cancer found that the presence of a mutation in any one of three genes, all known to be involved in DNA damage repair, was associated with complete pathologic response to cisplatin-based neoadjuvant chemotherapy as measured by pathological downstaging at the time of bladder surgery.

29 Jul 2024

Researchers find the effect of pesticides on increased cancer risk is comparable to smoking for some cancers

Researchers comprehensively evaluated the impact of pesticide use on cancer development in the United States.

29 Jul 2024

Pesticide use in agriculture may pose cancer risks similar to smoking

In modern day agriculture, pesticides are essential to ensure high enough crop yields and food security.

25 Jul 2024

Saffron: A golden remedy for modern health challenges

Review highlights saffron's potential in preventing and treating various human diseases through its bioactive compounds. Clinical and preclinical studies confirm saffron's benefits in conditions like maculopathy, depression, neurodegenerative diseases, and cancer.

21 Jul 2024

Study: 40% of cancer cases in the U.S. attributable to modifiable risk factors

A new study led by researchers at the American Cancer Society (ACS) finds four in 10 cancer cases and about one-half of all cancer deaths in adults 30 years old and older in the United States (or 713,340 cancer cases and 262,120 cancer deaths in 2019) could be attributed to modifiable risk factors, including cigarette smoking, excess body weight, alcohol consumption, physical inactivity, diet, and infections.

11 Jul 2024