CRISPR News and Research

Latest CRISPR News and Research

Researchers uncover new prognostic marker and possible therapeutic target for Ewing's sarcoma

Researchers of the Sarcoma research group of the Bellvitge Biomedical Research Institute, led by Dr. Òscar Martínez-Tirado, have first described the methylation profile of Ewing's sarcoma, a cancer of bone and soft tissues that mainly affects children and teenagers.

1 Dec 2016

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

CRISPR/Cas9, a powerful genome editing tool, is showing promise for efficient correction of disease-causing mutations.

1 Dec 2016

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

The Allen Institute for Cell Science has released the Allen Cell Collection: the first publicly available collection of gene edited, fluorescently tagged human induced pluripotent stem cells that target key cellular structures with unprecedented clarity.

30 Nov 2016

MEMOIR can help read history and ‘family trees’ of cells

Researchers have developed a new method for reading the history and "family trees" of cells.

22 Nov 2016

Researchers unravel puzzle of necroptosis

Cell death is an essential physiological process for all multicellular organisms. Throughout life, cells in many tissues die naturally and are replaced by new cells.

8 Nov 2016

UNC scientists find clue that may help explain why people differ in ability to survive arterial blockages

Researchers at the University of North Carolina School of Medicine have found a major clue that may explain why some people sustain relatively little damage from strokes or heart attacks despite severe arterial blockages.

7 Nov 2016

Yale researchers use new gene editing technique to correct mutations that cause thalassemia

A Yale-led research team used a new gene editing strategy to correct mutations that cause thalassemia, a form of anemia.

26 Oct 2016

Researchers use new gene-editing system to hasten quest to cure HIV+ patients

Researchers at UC San Francisco and the academically affiliated Gladstone Institutes have used a newly developed gene-editing system to find gene mutations that make human immune cells resistant to HIV infection.

26 Oct 2016

Texas Biomed researcher seeks to identify molecular mechanisms underlying early atherosclerosis

Texas Biomedical Research Institute Staff Scientist Dr. Genesio Karere was recently awarded a $609,568 grant from the National Institutes of Health to study and identify molecular mechanisms underlying early atherosclerosis.

25 Oct 2016

Novel ‘gene therapy in a box’ could effectively deliver modified blood stem cells

A table-top device that enables medical staff to genetically manipulate a patient's blood to deliver potential new therapies for cancer, HIV and other diseases would eliminate the need for multi-million-dollar "clean rooms," making gene therapy more possible for even the poorest of countries.

24 Oct 2016

Penn researchers identify new immune system mechanism to fight against infections

The innate immune system serves as a first-line defense, responding to infections almost immediately after a pathogen makes its way into the body.

17 Oct 2016

Researchers develop mouse model to investigate behavioral effects of eating disorder gene

Giving mice a gene mutation linked to eating disorders in people causes feeding and behavior abnormalities similar to symptoms often seen in patients with eating disorders. Only female mice are affected by the gene mutation, and some of the abnormalities in the female mice depend on whether they are housed alone or together with other mice.

13 Oct 2016

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of affected patients.

12 Oct 2016

Scientists aim to explore parasite's genomic architecture for varying expression of antigens

Many serious diseases such as malaria or AIDS present a major challenge for medicine because the causative pathogens use the same strategy although they are completely different: By camouflaging themselves they evade the immune system.

6 Oct 2016

Imran Noorani receives Brainlab Community Neurosurgery Abstract Award at 2016 CNS annual meeting

Imran Noorani MD, MRCS, of Cambridge, England, received the Brainlab Community Neurosurgery Abstract Award at the Congress of Neurological Surgeons Annual Meeting in San Diego.

28 Sep 2016

Synthego introduces CRISPRevolution synthetic sgRNA kit for fast, high-throughput gene editing

Synthego, a leading provider of genome engineering solutions, today announces the world’s first synthetic single guide RNA (sgRNA) CRISPR genome editing kit.

24 Sep 2016

Gene therapy may be viable approach for treating CF lung problems

Two new studies from the University of Iowa suggest that gene therapy may be a viable approach for treating or preventing lung disease caused by cystic fibrosis.

20 Sep 2016

Researchers identify genetic switch that may be potential target for Alzheimer's disease

A team at the MRC Clinical Sciences Centre, based at Imperial College London, has found an important part of the machinery that switches on a gene known to protect against Alzheimer's Disease.

20 Sep 2016

Novel DNA-altering method could lead to more treatment options for diseases

Researchers in Singapore have developed a new protein that can alter DNA in living cells with much higher precision than current methods.

13 Sep 2016

IWGAV establishes strategic recommendations for validating antibody specificity

The International Working Group on Antibody Validation, an independent group of international scientists with diverse research interests in the field of protein biology, today announced the publication of initial strategies developed to address a critical unmet need for antibody specificity, functionality and reproducibility in the September online issue of Nature Methods.

8 Sep 2016

CRISPR News and Research

Latest CRISPR News and Research

Researchers uncover new prognostic marker and possible therapeutic target for Ewing's sarcoma

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

Allen Institute for Cell Science releases gene edited, fluorescently tagged human iPS cells

MEMOIR can help read history and ‘family trees’ of cells

Researchers unravel puzzle of necroptosis

UNC scientists find clue that may help explain why people differ in ability to survive arterial blockages

Yale researchers use new gene editing technique to correct mutations that cause thalassemia

Researchers use new gene-editing system to hasten quest to cure HIV+ patients

Texas Biomed researcher seeks to identify molecular mechanisms underlying early atherosclerosis

Novel ‘gene therapy in a box’ could effectively deliver modified blood stem cells

Penn researchers identify new immune system mechanism to fight against infections

Researchers develop mouse model to investigate behavioral effects of eating disorder gene

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

Scientists aim to explore parasite's genomic architecture for varying expression of antigens

Imran Noorani receives Brainlab Community Neurosurgery Abstract Award at 2016 CNS annual meeting

Synthego introduces CRISPRevolution synthetic sgRNA kit for fast, high-throughput gene editing

Gene therapy may be viable approach for treating CF lung problems

Researchers identify genetic switch that may be potential target for Alzheimer's disease

Novel DNA-altering method could lead to more treatment options for diseases

IWGAV establishes strategic recommendations for validating antibody specificity

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut