CRISPR News and Research

Latest CRISPR News and Research

Researchers describe important step toward gene therapy for patients with Sandhoff disease

Babies with the rare, deadly genetic disorder Sandhoff disease begin to miss developmental milestones just months after birth. Lacking muscle tone, they never learn to sit up, develop heads too large to lift and eventually suffer uncontrollable seizures. There is no cure.

22 Feb 2018

Benson Hill Biosystems granted patent for novel genome editing system

The U.S. Patent and Trademark Office has granted Benson Hill Biosystems Patent No. 9,896,696 related to CRISPR 3.0 Cms1 genome editing nucleases, further expanding the company's suite of genomics tools to accelerate crop performance improvements.

20 Feb 2018

Lab-grown cerebellar cells may help explain how ASD develops at molecular level

Increasing evidence has linked autism spectrum disorder with dysfunction of the brain's cerebellum, but the details have been unclear. In a new study, researchers at Boston Children's Hospital used stem cell technology to create cerebellar cells known as Purkinje cells from patients with tuberous sclerosis complex, a genetic syndrome that often includes ASD-like features.

19 Feb 2018

Gene editing tool used to detect cancer

Researchers have developed a DNA detection system that can detect the presence of bacterial and viral DNA, which could be a valuable diagnostic tool for a range of disorders.

16 Feb 2018

Using CRISPR To Produce Induced Pluripotent Stem Cells

An interview with Dr. Sheng Ding about using a modified version of the CRISPR-Cas9 system to produce induced pluripotent stem cells.

9 Feb 2018

Scientists develop ultrasound-propelled nanomotors for active delivery of Cas9-sgRNA complex

In cancer research, the “Cas-9–sgRNA” complex is an effective genomic editing tool, but its delivery across the cell membrane to the target (tumor) genome has not yet been satisfactorily solved. American and Danish scientists have now developed an active nanomotor for the efficient transport, delivery, and release of this gene scissoring system.

9 Feb 2018

Scientists identify special pair of RNA scissors with many functions

CRISPR/Cas systems are known as promising "gene scissors" in the genome editing of plants, animals, and microorganisms by targeting specific regions in their DNA - and perhaps they can even be used to correct genetic defects.

8 Feb 2018

New CRISPR gene-editing technique can correct majority of mutations that cause DMD

Scientists have developed a CRISPR gene-editing technique that can potentially correct a majority of the 3,000 mutations that cause Duchenne muscular dystrophy (DMD) by making a single cut at strategic points along the patient's DNA, according to a study from UT Southwestern Medical Center.

6 Feb 2018

Next-generation ‘active genetics’ tool opens new horizons

In 2015, University of California San Diego biologists Ethan Bier and Valentino Gantz developed a breakthrough technology known as "active genetics," which results in parents transmitting a genetic trait to most of their offspring (instead of 50 percent receiving the trait under standard inheritance).

6 Feb 2018

Researchers report technical advances in production of HIV vaccines

Research on HIV over the past decade has led to many promising ideas for vaccines to prevent infection by the AIDS virus, but very few candidate vaccines have been tested in clinical trials.

6 Feb 2018

Novel method can edit genes with substantially fewer errors

Gene therapy is an emerging strategy to treat diseases caused by genetic abnormalities. One form of gene therapy involves the direct repair of a defective gene, using genome-editing technology such as CRISPR-Cas9. Despite its therapeutic potential, genome editing can also introduce unwanted and potentially harmful genetic errors that limit its clinical feasibility.

5 Feb 2018

The effects of Huntington’s disease can be seen as early as conception, finds new study

In a breakthrough study, scientists at the Rockefeller University have observed the effects of Huntington’s disease in neurons as early as conception.

30 Jan 2018

Rockefeller scientists develop system to model Huntington’s in human embryonic stem cells

With new findings, scientists may be poised to break a long impasse in research on Huntington's disease, a fatal hereditary disorder for which there is currently no treatment.

29 Jan 2018

Sugar-attaching enzyme found to be abundant in colon cancer cells

Researchers have identified an enzyme that is absent in healthy colon tissue but abundant in colon cancer cells, according to a report in the Jan. 26 issue of the Journal of Biological Chemistry.

27 Jan 2018

Study reveals existence of previously unknown immune defense mechanisms in bacteria

Until a decade ago, scientists were not aware that bacteria had complex immune systems – ones that could keep up with the pace of evolution in viruses called phages that infect bacteria.

27 Jan 2018

Mosquitoes can rapidly learn and remember the smell of hosts, study shows

Your grandmother's insistence that you receive more bug bites because you're 'sweeter' may not be that far-fetched after all, according to pioneering research from Virginia Tech scientists.

25 Jan 2018

UCSF researchers find new way to attack common drivers of 'undruggable' cancers

Cancer researchers have made great strides in developing targeted therapies that treat the specific genetic mutations underlying a patient's cancer.

24 Jan 2018

Scientists aim to decipher language of DNA

Yes, DNA has its own language and scientists want to understand it to apply personalized therapeutic solutions based on the analysis of the individual's genomic biomarkers and their regulation.

24 Jan 2018

Chinese researchers develop multifunctional vehicle to transport gene therapeutics

Gene editing is one of the hottest topics in cancer research. A Chinese research team has now developed a gold-nanoparticle-based multifunctional vehicle to transport the "gene scissors" to the tumor cell genome.

22 Jan 2018

Research provides insights into mechanisms governing healthy longevity

Keio University Global Research Institute, Tokyo publishes the January 2018 issue of KGRI Research Frontiers that includes researcher video profiles of Keio University researchers and research highlights from high impact publications including 'Regenerative medicine needs collaboration in and out of science in order to face current and future challenges; ‘Does eating fish protect you from depression?’; ‘Insights into the molecular mechanisms leading to kidney dysfunction in diabetic patients’; and ‘Ageing to 100 and beyond: Insights from demographic, phenotypic and genetic studies.

12 Jan 2018

CRISPR News and Research

Latest CRISPR News and Research

Researchers describe important step toward gene therapy for patients with Sandhoff disease

Benson Hill Biosystems granted patent for novel genome editing system

Lab-grown cerebellar cells may help explain how ASD develops at molecular level

Gene editing tool used to detect cancer

Using CRISPR To Produce Induced Pluripotent Stem Cells

Scientists develop ultrasound-propelled nanomotors for active delivery of Cas9-sgRNA complex

Scientists identify special pair of RNA scissors with many functions

New CRISPR gene-editing technique can correct majority of mutations that cause DMD

Next-generation ‘active genetics’ tool opens new horizons

Researchers report technical advances in production of HIV vaccines

Novel method can edit genes with substantially fewer errors

The effects of Huntington’s disease can be seen as early as conception, finds new study

Rockefeller scientists develop system to model Huntington’s in human embryonic stem cells

Sugar-attaching enzyme found to be abundant in colon cancer cells

Study reveals existence of previously unknown immune defense mechanisms in bacteria

Mosquitoes can rapidly learn and remember the smell of hosts, study shows

UCSF researchers find new way to attack common drivers of 'undruggable' cancers

Scientists aim to decipher language of DNA

Chinese researchers develop multifunctional vehicle to transport gene therapeutics

Research provides insights into mechanisms governing healthy longevity

Mastering plasmid production for genetic engineering and therapeutic research eBook

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?