Chronic Obstructive Pulmonary Disease News and Research

Latest Chronic Obstructive Pulmonary Disease News and Research

Results of Phase IIb dose range finding of oglemilast in chronic obstructive pulmonary disease announced

Forest Laboratories, Inc. (NYSE: FRX) and Glenmark Pharmaceuticals S.A. (Switzerland), a wholly owned subsidiary of Glenmark Pharmaceuticals India (GPL) today announced top-line results from a Phase IIb dose range-finding study of oglemilast in patients with Chronic Obstructive Pulmonary Disease (COPD). Once-daily treatment with oglemilast did not show a statistically meaningful increase from baseline compared to placebo in the primary endpoint trough FEV1, a measure of pulmonary function that is decreased in patients with COPD. Oglemilast was well tolerated at all doses studied.

19 Aug 2009

Amira Pharmaceuticals submits IND for inflammatory and allergic disease treatment candidate

Amira Pharmaceuticals, Inc. announced today the submission of an Investigational New Drug application (IND) of AM461, its internally-discovered, oral drug candidate for the treatment and control of inflammatory and allergic disease linked to the arachidonic acid pathway, to the U.S. Food and Drug Administration.

19 Aug 2009

Tiotropium - corticosteroid combination improves lung disease survival

Sufferers of chronic obstructive pulmonary disease have a greater chance of survival when treated with a combination of drugs that includes tiotropium, according to research at the University of Illinois at Chicago.

12 Aug 2009

New nutrition practice guidelines for patients with spinal cord injury

The American Dietetic Association has published new evidence-based nutrition practice guidelines for registered dietitians on nutrition care for patients with spinal cord injury.

12 Aug 2009

Gtx, Inc. reports Q2 2009 results

GTx, Inc. (Nasdaq: GTXI) today reported financial results for the second quarter of 2009. The net loss for the second quarter and six months ended June 30, 2009 was $11.3 million and $22.6 million, respectively, compared with a net loss of $13.2 million and $26.0 million for the same periods in 2008. At June 30, 2009 GTx had cash, cash equivalents and short-term investments of $68.9 million.

10 Aug 2009

Convent focuses on different approach to end-of-life care

A focus on end-of-life care emphasizes social and spiritual elements over aggressive medical intervention.

9 Jul 2009

Soy consumption and risk of COPD and respiratory symptoms

People who eat lots of soy products have better lung function and are less likely to develop the smoking-associated lung disease COPD (Chronic Obstructive Pulmonary Disease). A study published in BioMed Central’s open access journal Respiratory Research has shown that consumption of a wide variety of soy products can be associated with a reduction in the risk of COPD and other respiratory symptoms.

28 Jun 2009

Cigarette smoking does not affect everyone in same way

Cigarette smoking induced COPD, or chronic obstructive pulmonary disease, is a disease that results in severe breathing difficulty. According to World Health Organization (WHO) it is the fourth leading killer worldwide. However the mechanisms responsible for some smokers developing COPD and others evading the disease have not been well understood.

4 Jun 2009

COPD patients benefit from lifestyle program

Patients with moderate COPD were randomized to receive "usual care" or to undergo an interdisciplinary, community-based program (INTERCOM) that offered an intensive lifestyle moderation phase of four months, during which patients were instructed in detail to perform two 15-minute intervals of pleasurable walking or cycling, and offered instruction in other lifestyle changes such as nutrition and smoking cessation.

20 May 2009

Exposure to tobacco smoke early in life may lead to emphysema later on

The take-home message from our analysis is that exposure to tobacco smoke during childhood may be associated with detectable differences in lung structure, and perhaps early emphysema, later in life among people who do not themselves smoke.

19 May 2009

Women more susceptible to damaging effects of smoking than men

Women may be more susceptible to the lung damaging effects of smoking than men, according to new research by Inga-Cecilie Soerheim, M.D., and her colleagues from Channing Laboratory, Brigham and Women's Hospital and University of Bergen, Norway.

18 May 2009

Self-treatment lowers overall health care costs for chronic obstructive pulmonary disorder sufferers

Individuals suffering from chronic obstructive pulmonary disorder (COPD) can experience significant savings in healthcare costs by employing a self-treatment program with the judicious use of medications, according to the results of a new study. The self-treatment program achieves these savings by reducing the duration of flare-ups.

17 May 2009

Pioneering new tests and treatments for tackling airways disease highlighted

Pioneering new tests and treatments developed in Leicester for people with conditions like asthma and chronic cough are to be presented at a public event at the University of Leicester.

7 May 2009

FDA licenses Sanofi Pasteur's new flu vaccine manufacturing facility

Sanofi Pasteur announced today that the U.S. Food and Drug Administration (FDA) has licensed its new influenza vaccine manufacturing facility.

7 May 2009

New findings on COX-2 inhibitor side effects

In searching for a simple way to identify individuals with smoking-related lung injury, scientists at Weill Cornell Medical College have stumbled upon a potential explanation for why the class of pain-relievers known as COX-2 inhibitors increases the risk of heart problems among users.

29 Apr 2009

Different treatment options in chronic coronary artery disease

Sometimes cardiologists and cardiac surgeons can agree! There is often disagreement between the professions of cardiology and cardiac surgery about the proper therapy for coronary artery disease (CAD)-and this can harm the patient.

27 Apr 2009

Nanosensor arrays ''sniff out" cancer

In 2006 researchers established that dogs could detect cancer by sniffing the exhaled breath of cancer patients. Now, using nanoscale arrays of detectors, two groups of investigators have shown that a compact mechanical device also can sniff out lung cancer in humans.

27 Apr 2009

Muscle deterioration in patients with lung disease connected to high carbon dioxide levels in blood

Muscle deterioration in patients with lung diseases might be a direct consequence of high carbon dioxide levels in their blood, an international team of researchers headed by Prof. Yosef Gruenbaum of the Hebrew University of Jerusalem has found.

23 Apr 2009

Double-lung transplants work better than single for long-term survival

Having both lungs replaced instead of just one is the single most important feature determining who lives longest after having a lung transplant, more than doubling an organ recipient's chances of extending their life by over a decade, a study by a team of transplant surgeons at Johns Hopkins shows.

22 Apr 2009

Combination inhaler might simplify asthma treatment

People suffering from chronic asthma might have a new treatment option that allows them to manage their condition with a single prescribed inhaler that contains two medicines, according to a new review.

14 Apr 2009