Colon Cancer

Every year, about one million new cases of colon cancer are diagnosed worldwide. About 150,000 new cases are detected each year in the United States. Over a lifetime, about 1 in 19 people develop colon cancer and nearly 50,000 people are expected to die from it in the U.S. this year.

What Causes Colorectal Cancer?

Cancer occurs when a normal cell divides and multiples uncontrollably. Normally cells are regulated in their growth, maturity, division and death by the DNA present in their nucleus. With damage to the DNA the cells may become rogue and multiply uncontrollably to give rise to tumors.

Colorectal Cancer Management

What is Colorectal Cancer?

Colorectal Cancer Prognosis

Colorectal Cancer Diagnosis

Colorectal Cancer Symptoms

Colorectal Cancer Prevention

Latest Colon Cancer News and Research

Only 15% of eligible American adults discuss lung cancer screening with their doctors

Lung cancer screenings can save lives by detecting cancer in its early stages, but only 15% of eligible American adults have discussed the screening with their doctors, according to data analysis performed by University of Cincinnati Cancer Center researchers.

21 Aug 2026

Blocking ZFP36L2 protein may disrupt colorectal cancer metastatic growth

Digestion is hard on the cells that line the human gut, and they are constantly being shed and replaced. This renewal is driven by a population of tireless stem cells.

5 Aug 2026

Arginine boosts immune defenses against cancer and viral infections

The amino acid arginine helps to keep the human body humming, most notably by synthesizing proteins that carry out a range of cellular processes.

31 Jul 2026

New photothermal therapy overcomes major cancer treatment barriers

In a promising development for cancer treatment, a collaborative research team has overcome two issues that have prevented photo thermal therapy, a much less invasive treatment option than surgery and/or radiation, from becoming more common.

22 Jul 2026

Ketogenic diet may increase small intestine cancer risk in mice

A high-fat, low-carbohydrate diet, also called a ketogenic diet, can help some people lose weight by forcing their bodies to burn fat for fuel instead of sugar.

15 Jul 2026

Machine learning framework enables low-cost water toxin detection

Portable screen-printed carbon electrode (SPCE) biosensors offer a rapid and low-cost way to detect microcystin-lysine-arginine (MC-LR), an extremely potent toxin produced by cyanobacteria during harmful algal blooms in freshwater.

11 Jul 2026

Scientists map how cellular senescence and stemness interact in disease

A new review was published in Volume 18 of Aging on May 30, 2026, titled "The love and hate relationship between cellular senescence and stemness."

29 Jun 2026

Lipid nanoparticles enhance immune response against lung cancer

Researchers at the University of Arizona R. Ken Coit College of Pharmacy have developed a new strategy that helps the immune system recognize and attack lung cancer tumors more effectively.

25 Jun 2026

GATA6 loss transforms colorectal cancer cells into metastatic states

Loss of GATA6-a transcription factor that controls which genes are turned on or off-can reprogram colorectal cancer cells into more primitive, adaptable states that can then spread to the liver and establish new tumors, according to Weill Cornell Medicine and Massachusetts Institute of Technology researchers.

22 Jun 2026

New drug could double survival time in patients with advanced pancreatic cancer

A new medication could double survival time in patients with advanced pancreatic cancer, according to Phase III clinical trial results presented at the American Society of Clinical Oncology (ASCO) 2026 annual meeting and simultaneously published in The New England Journal of Medicine.

22 Jun 2026

Gene deletion exposes hidden colon cancer cells to immunotherapy attack

A study from the University of Calgary shows that removing a single gene makes colon cancer cells a target for immunotherapy - a fundamental breakthrough.

18 Jun 2026

Evidence strengthens connection between alcohol and pancreatic cancer

A new paper led by researchers at University of Victoria's Canadian Institute for Substance Use Research (CISUR) contributes to mounting evidence that alcohol use can cause pancreatic cancer.

16 Jun 2026

New genetic driver found for rare small intestinal cancers

A signaling system known as the Wnt pathway plays a central role in how cells in the intestine grow, divide, and renew themselves.

12 Jun 2026

FDA accepts immunotherapy drug for review in colon cancer treatment

The Alliance for Clinical Trials in Oncology (Alliance) today announced that the U.S. Food and Drug Administration has accepted for review Genentech's supplemental Biologic License Application for their immunotherapy drug atezolizumab (Tecentriq®) for the treatment of patients with stage III colon cancer with deficient deoxyribonucleic acid (DNA) mismatch repair (dMMR).

11 Jun 2026

Prospective study compares three robotic platforms for colon resection

Since the introduction of the Da Vinci robotic system, robot-assisted colon resection has gained popularity because of its the potential technical advantages.

11 Jun 2026

Sting signaling stimulates vital immune defenses to actively suppress aggressive tumor growth

A new review brings attention to the STING pathway as a critical regulator in both colitis and colon cancer, highlighting its complex and often opposing roles in inflammation and tumor development. The findings underscore how this key component of the innate immune system can act as both a driver of disease and a protective mechanism, depending on biological context.

25 May 2026

Targeting tumor-specific inflammatory process may prevent drug resistance in colon cancer

Chemotherapy drugs that target a common mutation in colorectal cancer rapidly lose efficacy in patients, leading to relapse.

21 May 2026

Common allergy medication may also help fight aggressive cancers

A drug widely used to treat asthma and allergies may also help fight aggressive cancers, reports a new Northwestern Medicine study that uncovered how tumors hijack common white blood cells to evade immunotherapy.

19 May 2026

Adult weight gain strongly linked to higher obesity-related cancer risk

New research presented at this year's European Congress on Obesity (ECO 2026) in Istanbul, Turkey (12-15 May) shows that people who gain the highest amount of weight across adulthood are at greatly increased risk of certain obesity related cancers.

13 May 2026

Copper-based nanoplatform shows promise against metastatic tumor growth

What happens if cancer cells lose both their mitochondrial energy supply and their glycolytic backup system? This question is central to a new study published in Research by researchers from Northwestern Polytechnical University and collaborating institutions.

10 May 2026