Colon Cancer

Every year, about one million new cases of colon cancer are diagnosed worldwide. About 150,000 new cases are detected each year in the United States. Over a lifetime, about 1 in 19 people develop colon cancer and nearly 50,000 people are expected to die from it in the U.S. this year.

What Causes Colorectal Cancer?

Cancer occurs when a normal cell divides and multiples uncontrollably. Normally cells are regulated in their growth, maturity, division and death by the DNA present in their nucleus. With damage to the DNA the cells may become rogue and multiply uncontrollably to give rise to tumors.

Colorectal Cancer Symptoms

What is Colorectal Cancer?

Colorectal Cancer Prevention

Colorectal Cancer Prognosis

Colorectal Cancer Diagnosis

Colorectal Cancer Management

Latest Colon Cancer News and Research

Scientists map how cellular senescence and stemness interact in disease

A new review was published in Volume 18 of Aging on May 30, 2026, titled "The love and hate relationship between cellular senescence and stemness."

29 Jun 2026

Lipid nanoparticles enhance immune response against lung cancer

Researchers at the University of Arizona R. Ken Coit College of Pharmacy have developed a new strategy that helps the immune system recognize and attack lung cancer tumors more effectively.

25 Jun 2026

GATA6 loss transforms colorectal cancer cells into metastatic states

Loss of GATA6-a transcription factor that controls which genes are turned on or off-can reprogram colorectal cancer cells into more primitive, adaptable states that can then spread to the liver and establish new tumors, according to Weill Cornell Medicine and Massachusetts Institute of Technology researchers.

22 Jun 2026

New drug could double survival time in patients with advanced pancreatic cancer

A new medication could double survival time in patients with advanced pancreatic cancer, according to Phase III clinical trial results presented at the American Society of Clinical Oncology (ASCO) 2026 annual meeting and simultaneously published in The New England Journal of Medicine.

22 Jun 2026

Gene deletion exposes hidden colon cancer cells to immunotherapy attack

A study from the University of Calgary shows that removing a single gene makes colon cancer cells a target for immunotherapy - a fundamental breakthrough.

18 Jun 2026

Evidence strengthens connection between alcohol and pancreatic cancer

A new paper led by researchers at University of Victoria's Canadian Institute for Substance Use Research (CISUR) contributes to mounting evidence that alcohol use can cause pancreatic cancer.

16 Jun 2026

New genetic driver found for rare small intestinal cancers

A signaling system known as the Wnt pathway plays a central role in how cells in the intestine grow, divide, and renew themselves.

12 Jun 2026

FDA accepts immunotherapy drug for review in colon cancer treatment

The Alliance for Clinical Trials in Oncology (Alliance) today announced that the U.S. Food and Drug Administration has accepted for review Genentech's supplemental Biologic License Application for their immunotherapy drug atezolizumab (Tecentriq®) for the treatment of patients with stage III colon cancer with deficient deoxyribonucleic acid (DNA) mismatch repair (dMMR).

11 Jun 2026

Prospective study compares three robotic platforms for colon resection

Since the introduction of the Da Vinci robotic system, robot-assisted colon resection has gained popularity because of its the potential technical advantages.

11 Jun 2026

Sting signaling stimulates vital immune defenses to actively suppress aggressive tumor growth

A new review brings attention to the STING pathway as a critical regulator in both colitis and colon cancer, highlighting its complex and often opposing roles in inflammation and tumor development. The findings underscore how this key component of the innate immune system can act as both a driver of disease and a protective mechanism, depending on biological context.

25 May 2026

Targeting tumor-specific inflammatory process may prevent drug resistance in colon cancer

Chemotherapy drugs that target a common mutation in colorectal cancer rapidly lose efficacy in patients, leading to relapse.

21 May 2026

Common allergy medication may also help fight aggressive cancers

A drug widely used to treat asthma and allergies may also help fight aggressive cancers, reports a new Northwestern Medicine study that uncovered how tumors hijack common white blood cells to evade immunotherapy.

19 May 2026

Adult weight gain strongly linked to higher obesity-related cancer risk

New research presented at this year's European Congress on Obesity (ECO 2026) in Istanbul, Turkey (12-15 May) shows that people who gain the highest amount of weight across adulthood are at greatly increased risk of certain obesity related cancers.

13 May 2026

Copper-based nanoplatform shows promise against metastatic tumor growth

What happens if cancer cells lose both their mitochondrial energy supply and their glycolytic backup system? This question is central to a new study published in Research by researchers from Northwestern Polytechnical University and collaborating institutions.

10 May 2026

Mailed DNA-based test for colorectal cancer screening

The use of mailed FIT-DNA kits in community health centers significantly increases colorectal cancer screening, though follow-up colonoscopy rates remain low.

30 Apr 2026

Rectal cancer deaths in older millennials are rising rapidly

Rectal cancer deaths among older millennials are accelerating, with growth in mortality far outpacing colon cancer, suggesting primary care doctors should fully investigate early symptoms in patients under age 45, according to a study to be presented at Digestive Disease Week (DDW) 2026.

23 Apr 2026

Coffee impacts the gut-brain axis to improve mood and stress

New research from APC Microbiome Ireland, a world leading research centre at University College Cork, has comprehensively explored the mechanisms behind coffee's positive effects on the gut-brain axis for the first time.

21 Apr 2026

Epigenetic changes allow cancer cells to shift identity and survive drugs

Cancer drugs are designed to shut tumors down. But sometimes, in the very act of attacking a tumor, treatment can also help a small fraction of cancer cells become harder to kill. A new study from researchers at the Institute for Systems Biology (ISB) shows that cancer cells may begin escaping therapy much earlier - as the therapy itself triggers a stress response that drives some cancer cells into a temporary drug-tolerant state.

16 Apr 2026

Stard7 plays unexpected role in intestinal cancer development

A new study led by researchers at the University of Liège highlights the unexpected role of Stard7 in the development of intestinal cancers.

2 Apr 2026

Advances in nanomedicine improve anthelmintic drug delivery and effectiveness

Announcing a new article publication in BIO Integration. According to World Health Organization (WHO) reports, parasitic infections substantially affect the world's population and are responsible for more than 16 million annual deaths in developing countries.

2 Apr 2026