Colon Cancer

Every year, about one million new cases of colon cancer are diagnosed worldwide. About 150,000 new cases are detected each year in the United States. Over a lifetime, about 1 in 19 people develop colon cancer and nearly 50,000 people are expected to die from it in the U.S. this year.

What Causes Colorectal Cancer?

Cancer occurs when a normal cell divides and multiples uncontrollably. Normally cells are regulated in their growth, maturity, division and death by the DNA present in their nucleus. With damage to the DNA the cells may become rogue and multiply uncontrollably to give rise to tumors.

Colorectal Cancer Symptoms

Colorectal Cancer Diagnosis

Colorectal Cancer Prognosis

Colorectal Cancer Management

Colorectal Cancer Prevention

What is Colorectal Cancer?

Latest Colon Cancer News and Research

Why smartphone use on the toilet may increase hemorrhoid risk

Adults using smartphones on the toilet spent significantly more time seated and had 46% higher odds of hemorrhoids on colonoscopy. The cross-sectional study suggests prolonged sitting, not straining, may be the key driver of hemorrhoid risk.

8 Sep 2025

Sugar-coated nanoparticles offer new hope for treating triple-negative breast cancer

Triple-negative breast cancer is particularly aggressive and difficult to treat; but recent research may offer a new way to target the often-deadly disease.

3 Sep 2025

Tumor microbiota identified as predictors of prognosis in gastrointestinal cancers

Microbes inside cancerous tumors can influence the spread of disease and the effectiveness of treatment. Those roles make them appealing targets for new therapies and offer ways to better predict risk.

28 Aug 2025

High protein diet linked to increased risk of cancer-associated venous thromboembolism

Next to cancer recurrence or progression, cardiovascular diseases are the leading causes of death in cancer survivors.

28 Aug 2025

New formulation of chemotherapy drug opens doors to advanced cancer treatment options

University of Arizona researchers devised a new method to deliver cancer chemotherapy drugs to pancreatic and breast cancer tumors more effectively and with less damage to healthy tissues than standard forms of chemotherapy.

21 Aug 2025

Nanodroplet array revolutionizes search for new drugs

Until now, the early phase of drug discovery for the development of new therapeutics has been both cost- and time-intensive.

21 Aug 2025

AI model detects genetic changes in colorectal cancer from tissue images

An international, interdisciplinary research team led by Prof. Jakob N. Kather from the Else Kröner Fresenius Center (EKFZ) for Digital Health at TUD Dresden University of Technology analyzed seven independent patient cohorts from Europe and the USA using their newly developed AI model.

20 Aug 2025

Colorectal cancer rates nearly triple among younger people in Sweden

According to a study by Karolinska Institutet, nearly three times as many people under the age of 50 in Sweden are diagnosed with colorectal cancer today compared with the early 1990s.

14 Aug 2025

Research finds long-term health challenges in survivors of childhood cancer

Researchers at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States with its National Medical Center ranked among the nation's top cancer centers by U.S. News & World Report, today published a new study which found that some survivors of childhood cancer are more at risk for serious health issues as they grow older, including new cancers and chronic conditions like heart disease.

11 Aug 2025

Lauric acid could be a key cancer-fighting compound in coconut oil

Virgin coconut oil and lauric acid show promise in inhibiting cancer cell growth and mitigating chemotherapy toxicity, paving the way for future therapies.

11 Aug 2025

DKK1 identified as key driver of immune resistance in bone metastases

Many major cancers, including those of the lung, breast and prostate gland, spread to the bones as they progress.

7 Aug 2025

Early screening linked to spike in early-stage colon cancer diagnoses

Recent study shows a significant increase in early-stage colorectal cancer among 45-49 year-olds, linked to new screening recommendations and pandemic effects.

7 Aug 2025

HOXB13 emerges as a context-dependent regulator in cancer biology

HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a double-edged sword in human cancer.

5 Aug 2025

Understanding the importance of B vitamins for health

Eight different vitamins make up the B complex, and they all play crucial roles in the body, such as producing energy, keeping our nervous system healthy, and supporting cell development.

4 Aug 2025

Beneficial gut bacteria found to suppress harmful microbes

Intestinal bacteria are important for human health as they help digest food and regulate immune function. Thus, in recent years, it has become clear that gut microbiota dysbiosis, an imbalance in types and composition of intestinal bacteria, is associated with digestive disorders and other diseases.

1 Aug 2025

Novel insights from lymphoid structures: Lessons from colorectal cancer research

Discover how lymphoid structures and germinal centers provide powerful prognostic insights into colorectal cancer.

From TissueGnostics 31 Jul 2025

Study identifies risk factors for second colorectal cancer in people with Lynch syndrome

A current study by the German Familial Colorectal Cancer Consortium is looking at the question of which people with Lynch syndrome are at an increased risk of developing a second colorectal cancer.

30 Jul 2025

Scientists discover neuron-like communication system in the gut

In a key advance for regenerative medicine and gut health, scientists from Duke-NUS Medical School and Nanyang Technological University, Singapore (NTU Singapore) have uncovered a precise and unexpected communication system in the gut.

24 Jul 2025

Targeting tumor cell stemness may hold the key to treating colon cancer more effectively

Colon cancer remains a major global health concern, ranking third among the most diagnosed cancers and leading causes of cancer-related death worldwide.

22 Jul 2025

New reviews highlight urgent need for GI cancer screening in younger adults

Early-onset gastrointestinal (GI) cancers are rising at alarming rates worldwide and, in the U.S., are increasing faster than any other type of early-onset cancer, including breast cancer, according to two recent literature reviews from Dana-Farber Cancer Institute.

17 Jul 2025