Colon Cancer

Every year, about one million new cases of colon cancer are diagnosed worldwide. About 150,000 new cases are detected each year in the United States. Over a lifetime, about 1 in 19 people develop colon cancer and nearly 50,000 people are expected to die from it in the U.S. this year.

What Causes Colorectal Cancer?

Cancer occurs when a normal cell divides and multiples uncontrollably. Normally cells are regulated in their growth, maturity, division and death by the DNA present in their nucleus. With damage to the DNA the cells may become rogue and multiply uncontrollably to give rise to tumors.

What is Colorectal Cancer?

Colorectal Cancer Diagnosis

Colorectal Cancer Prevention

Colorectal Cancer Management

Colorectal Cancer Prognosis

Colorectal Cancer Symptoms

Latest Colon Cancer News and Research

Novel microbiome-based diagnostic tool can identify liver fibrosis, cirrhosis

Chronic liver disease represents a major global public health problem affecting an estimated 844 million people, according to the World Health Organization. It is among the top causes of mortality in Australia, the UK and the United States.

2 Jul 2020

NIH spearheads study to test at-home screening for HPV and cervical cancer

With a tiny brush, briefly swab the vagina to collect cells. Then slide the swab into a screening kit and drop it into the mail.

1 Jul 2020

Novel fungal compound can turn on p53 gene in cancer cells

Cancers cells use a special technique to propagate; they delete their "programmed death" gene through mutation, "forget" to die when their lifetime is over, and continue to grow instead.

11 Jun 2020

Key recommendations on genetic testing of men for prostate cancer

Prostate cancer is a leading cause of death from cancer in the US and especially in the Philadelphia region. Consistently, Philadelphia has outpaced the state of PA and the nation in diagnoses and death from prostate cancer.

10 Jun 2020

Good vitamin D status can prevent cancer, improve prognosis of several cancers

A good vitamin D status is beneficial both in cancer prevention and in the prognosis of several cancers, according to a new research review.

10 Jun 2020

Study explores the role of mi RNAs in anticancer effect exerted by physical activity

Volume 11, Issue 22 of Oncotarget reported that the goal of this study was to explore the involvement of mi RNAs in beneficial effects exerted by physical activity in breast cancer prevention.

3 Jun 2020

New guidelines improve outcomes in colon cancer patients

A new University of Kentucky Markey Cancer Center study finds that many Kentucky patients with colon cancer are not receiving the recommended standard of care therapy for their disease.

3 Jun 2020

SARS-CoV-2 infected patients who undergo surgery experience worse postoperative outcomes

Patients undergoing surgery after contracting coronavirus are at greatly increased risk of postoperative death, a new global study published in The Lancet reveals.

2 Jun 2020

Update on PALLAS triaI evaluating adjuvant palbociclib for early breast cancer

The Austrian Breast & Colorectal Cancer Study Group, Alliance Foundation Trials, the Breast International Group, PrECOG, LLC, the German Breast Group, and the NSABP Foundation today announced that the independent Data Monitoring Committee for the global Phase 3 early breast cancer PALbociclib CoLlaborative Adjuvant Study trial determined that the study is unlikely to show a statistically significant improvement in the primary endpoint of invasive disease-free survival following a preplanned interim analysis.

1 Jun 2020

Oral antidiabetics improve outcomes in diabetics with colorectal cancer

Bottom Line: Among patients with both colorectal cancer and diabetes in Korea, those who had a high adherence to their oral diabetes medication had a significantly reduced risk of overall mortality compared with those with lower adherence.

1 Jun 2020

Targeted therapy pralsetinib shows high response rates in patients with RET fusion-positive cancers

The targeted therapy pralsetinib appears to have high response rates and durable activity in patients with a broad variety of tumors harboring RET gene fusions, according to results from the international Phase I/II ARROW trial, led by researchers at The University of Texas MD Anderson Cancer Center.

29 May 2020

First detailed study of the epigenetic landscape of human tumor organoids

Frequently, promising cancer therapies fail when applied to patients in the real clinical setting. This occurs despite many of these new treatments demonstrating promising results at the preclinical stage in the lab.

13 May 2020

Researchers identify new therapeutic target to switch-off cancer stem cells

Tumors are not a uniform mass of cells. Colon cancers bear differentiated-like cells, similar to the functional cells of the intestinal wall, and pluripotent cells--the so-called tumour stem cells.

13 May 2020

Scientists uncover important functions of a special protein during cell division

In a new study, researchers from the University of Copenhagen have discovered two important functions of a protein called RTEL1 during cell division.

12 May 2020

Indiana researchers identify new target for colorectal cancer immunotherapy

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified a target for colorectal cancer immunotherapy.

11 May 2020

RNA interference machinery influences epithelial cell biology

Epithelial cells are held together and connected by several different types of structures that form cell-cell contacts.

9 May 2020

Breakthrough study shows liquid biopsy test can safely detect 26 undiagnosed cancers

Results from a first-of-its-kind study of a multicancer blood test in more than 9,900 women with no evidence or history of cancer showed the liquid biopsy test safely detected 26 undiagnosed cancers, enabling potentially curative treatment.

29 Apr 2020

Making long-term research project a translational success

The Digital Health Accelerator (DHA) of the Berlin Institute of Health (BIH) is helping the scientists to make the long-term research project a translational success.

22 Apr 2020

Family history-based early screening may have dramatic impact on colorectal cancer detection

In an analysis that included information on adults diagnosed with colorectal cancer between 40 and 49 years of age, almost all patients could have been diagnosed earlier if they had been screened according to current family history-based screening guidelines.

20 Apr 2020

Bacterial metabolism of bile acids boosts generation of immune cells, study shows

A Ludwig Cancer Research study has discovered a novel means by which bacterial colonies in the small intestine support the generation of regulatory T cells--immune cells that suppress autoimmune reactions and inflammation.

15 Apr 2020