Crohn's Disease News and Research

Latest Crohn's Disease News and Research

New insight into ulcerative colitis

Social, environmental and dietary changes are associated with the changes of disease spectrum in a country. Ulcerative colitis has become a commonly seen disease in China, probably due to extensive consumption of Western foods in recent years.

14 Nov 2007

Threshold for colectomy may be too high, warn experts

The clinical threshold for undertaking elective surgery to remove part or all of the colon (colectomy) for people with inflammatory bowel disease (IBD) may be too high, warn researchers in a study published on bmj.com.

1 Nov 2007

Clinical threshold for inflammatory bowel disease surgery may be too high

31 Oct 2007

Infliximab scheduled treatment has proven to be an effective strategy in IBD patients

Crohn's disease (CD) and ulcerative colitis (UC) are chronic-relapsing diseases, the clinical courses of which are characterized by periods of remission and periods of acute flare up, determining clinical symptoms which have a strong impact on the quality of life for patients.

25 Oct 2007

New understanding of vagus nerve's role in regulating inflammation

It used to be dogma that the brain was shut away from the actions of the immune system, shielded from the outside forces of nature.

24 Oct 2007

Discovery of two genes linked to a disabling form of arthritis called ankylosing spondylitis

An international team of researchers led by a Fred Hutchinson Cancer Research Center geneticist has discovered two genes linked to a disabling form of arthritis called ankylosing spondylitis, a painful and progressive disease in which some or all of the spine's vertebrae fuse together.

22 Oct 2007

Phase II map of human genetic variation

The International HapMap Consortium today published analyses of its second-generation map of human genetic variation, which contains three times more markers than the initial version unveiled in 2005.

18 Oct 2007

New analyses of long-term LIALDA (mesalamine) data presented at ACG

Post-hoc and other analyses of secondary endpoints of a long-term safety and tolerability study of Shire plc's ulcerative colitis (UC) drug LIALDA (mesalamine) provide further data on LIALDA in patients with mild to moderate ulcerative colitis.

16 Oct 2007

Mesalamine linked to cancer protection for high risk inflammatory bowel disease patients

Researchers found that mesalamine use among patients with inflammatory bowel disease was associated with a decrease in incidence of colorectal cancer when comparing cases and controls.

16 Oct 2007

Capsule endoscopy finds undiagnosed Crohn's disease

A small capsule that takes "snapshots" of the small intestine as it moves through the digestive tract helped doctors spot cases of Crohn's disease that had gone undiagnosed for up to 15 years, according to researchers at Wake Forest University Baptist Medical Center.

16 Oct 2007

Specific immune deficiency pinpointed as likely cause of ulcerative colitis

In a series of mouse experiments, researchers at the Harvard School of Public Health (HSPH) have pinpointed a specific immune deficiency as the likely fundamental cause of ulcerative colitis, a chronic, sometimes severe inflammatory disease of the colon or large intestine that afflicts half a million Americans.

4 Oct 2007

Indian bug is the ancestor of Crohn's disease pathogen

An Indian team of researchers led by Seyed E. Hasnain of the Institute of Life Sciences (ILS), University of Hyderabad, India has found that a seemingly unknown mycobacterial organism Mycobacterium indicus pranii (MIP) could be the earliest ancestor of the 'generalist' branch of mycobacterial pathogens.

3 Oct 2007

Clostridium difficile infection is four times more likely to kill patients with inflammatory bowel disease

C difficile is an important cause of diarrhoea among inpatients, and the numbers of new cases of the infection have been steadily increasing in recent years.

27 Sep 2007

Capsule endoscopy best for diagnosing Crohn's disease

Research from La Fe University Hospital in Valencia, Spain shows that capsule endoscopy diagnoses more Crohn's disease recurrence after surgery than colonoscopy.

27 Sep 2007

It's back to the dark ages...hookworms to treat asthma!

Modern medicine may have stopped short of blood-letting, leeches and purges but parasitic worms could be making a come-back!

17 Sep 2007

Do not ignore fatigue

Jennifer Sieck knew something had to be done when she would lie in bed most of the day and night.

5 Sep 2007

E. coli bacteria linked to Crohn's disease

A team of Cornell University scientists from the College of Veterinary Medicine, Weill Cornell Medical College and the College of Agriculture and Life Sciences have discovered that a novel group of E. coli bacteria, containing genes similar to those described in uropathogenic and avian pathogenic E. coli and enteropathogenic bacteria such as salmonella, cholera, bubonic plague, is associated with intestinal inflammation in patients with Crohn's disease in their research paper published July 12 by the ISME Journal: Multidisciplinary Journal of Microbial Ecology.

8 Aug 2007

Biologic agents valuable treatment option for patients with inflammatory bowel disease

The use of biologic agents for the treatment of inflammatory bowel disease (IBD) may benefit patients, but doctors need to consider the potential associated side effects in determining treatment course, according to a consensus paper published in this month's issue of Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.

26 Jul 2007

New drug shows promise in treating Crohn's disease

According to two new studies the drug certolizumab has proved to be a safe and effective treatment for moderate-to-severe Crohn's disease.

21 Jul 2007

Prevention and treatment of vitamin D deficiency

Boston, MA:In a review article to appear in the July 19th issue of the New England Journal of Medicine, Dr. Michael Holick, an internationally recognized expert in vitamin D, provides an overview of his pioneering work that expounds on the important role vitamin D plays in a wide variety of chronic health conditions, as well as suggesting strategies for the prevention and treatment of vitamin D deficiency.

19 Jul 2007