Crohn's Disease

Crohn’s disease is a chronic inflammatory disease of the bowel affecting at least 115,000 people in the UK. The condition usually develops in teenagers and young adults, but can be diagnosed at any age and is equally common in men and women.

What is Crohn's Disease?

Crohn’s disease is essentially a disease that leads to severe inflammation of the lining of the digestive system.

Crohn's Disease Symptoms

Crohn's Disease Cause

Crohn's Disease Diagnosis

Crohn's Disease Treatment

Crohn's Disease Complications

History of Crohn's Disease

Intestinal Mycoplasma and Crohn's Disease

Latest Crohn's Disease News and Research

Simple screening tool reveals the prevalence of malnutrition among patients at UNC’s IBD clinic

Eating food and absorbing its nutrients is an everyday occurrence, but this normal activity can look different for someone who suffers from inflammatory bowel disease.

8 Dec 2023

New biomarker for inflammatory bowel disease identified through reverse metabolomics

In recent years, microbiome research has started to shift its focus from the microbes themselves to the molecules they produce.

5 Dec 2023

Depression, constipation, and UTIs may be early signs of multiple sclerosis

In some diseases, the underlying processes can start years before a diagnosis is made. A new study finds that people who later develop multiple sclerosis (MS) are more likely to have conditions like depression, constipation and urinary tract infections five years before their MS diagnosis than people who do not develop MS.

5 Dec 2023

Fiber-free diet key to treating childhood Crohn's disease, new study finds

Research reveals how a fiber-free diet in Exclusive Enteral Nutrition (EEN) helps treat Crohn's disease in children by affecting the intestinal pathobiont Mucispirillum schaedleri. It shows that this diet alters gut microbiota, reducing Mucispirillum's pathogenicity and aiding in managing colitis.

26 Nov 2023

AGA guideline recommends biomarkers for Crohn's disease management

The American Gastroenterological Association (AGA) released a new evidence-based guideline recommending the use of blood and stool-based biomarkers to help manage Crohn's disease, a type of inflammatory bowel disease (IBD).

17 Nov 2023

New research reveals broccoli sprouts may alleviate Crohn's disease symptoms in youth

The impact of broccoli sprouts and its role in resolving Crohn’s disease symptoms.

14 Nov 2023

Blood tests can detect inflammatory bowel disease years before symptoms appear

Researchers at the Francis Crick Institute and Aalborg University in Copenhagen have shown that changes can be detected in blood tests up to eight years before a diagnosis of Crohn's disease and up to three years before a diagnosis of ulcerative colitis.

7 Nov 2023

Shifting towards personalized treatment approaches for chronic inflammatory diseases

Chronic inflammatory diseases affect 5% to 7% of the population, regardless of age or sex, from children to the elderly.

6 Nov 2023

Microscopic inflammation in IBD linked to higher risk of serious infections

Inflammatory bowel disease (IBD) is an independent risk factor for serious infection, even at very low levels of gastrointestinal inflammation.

1 Nov 2023

Fungi used to produce food products have potential probiotic effects on gut inflammation

Many fungus strains have been used and selected by the food industry for their capacities to ferment, produce flavors or produce heterologous molecules.

26 Oct 2023

Does inflammatory bowel disease have a causal relationship with extracolonic tumors?

Whether inflammatory bowel disease (IBD) is causally related to extracolonic cancers.

17 Oct 2023

Research suggests potential connection between gut bacteria and onset of colorectal lesions and cancers

New research has identified significant variations in the gut microbiome of individuals who developed pre-cancerous colonic lesions, suggesting a potential connection between gut bacteria and the onset of colorectal lesions and cancers.

15 Oct 2023

Beyond the gut: Crohn's disease's oral clues for timely diagnosis

The oral manifestations of CD.

12 Oct 2023

COVID-19 heightens risk of autoimmune disorders

SARS-CoV-2 infection may elevate risk for certain autoimmune disorders, suggests study. Regular post-COVID monitoring needed to detect and manage potential autoimmune consequences.

9 Oct 2023

Is there an association between psoriasis onset and risk of autoimmune disease?

Researchers evaluated new-onset autoimmune disease risk among individuals with new-onset psoriatic illness.

9 Oct 2023

Oral lipid nanoparticle drug shows promise for preventing colitis-associated cancer in mice

An oral lipid nanoparticle drug prevents tumor development in mice, suggesting this is a promising drug formulation for preventing colitis-associated cancer, according to a study led by researchers in the Institute for Biomedical Sciences at Georgia State University.

4 Oct 2023

Specialized gut immune cells could be new biomarker for IBD progression

Researchers at the Francis Crick Institute, King's College London and Guy's and St Thomas' NHS Foundation Trust have characterised a specialised type of immune cell, which plays a key role in protecting and repairing the cells in the healthy human gut.

14 Sep 2023

Loneliness, depression and social isolation linked to digestive diseases in older adults

While life expectancy rates for older Americans are rising, nearly 40% of adults report living with a digestive disease of some kind.

12 Sep 2023

“Inverse vaccine” shows promise to reverse autoimmune diseases without shutting down rest of the immune system

A new type of vaccine developed by researchers at the University of Chicago's Pritzker School of Molecular Engineering (PME) has shown in the lab setting that it can completely reverse autoimmune diseases like multiple sclerosis, type 1 diabetes, and Crohn's disease -; all without shutting down the rest of the immune system.

12 Sep 2023

Scientists elucidate mechanism behind early loss of vaccination protection in people with autoimmune disease

People who are treated with TNF-α inhibitors for their autoimmune disease such as Crohn's disease or rheumatoid arthritis lose their vaccination protection significantly earlier than average.

7 Sep 2023

Crohn's Disease

Overview

Crohn's Disease Symptoms

Crohn's Disease Cause

Crohn's Disease Diagnosis