Crohn's Disease

Crohn’s disease is a chronic inflammatory disease of the bowel affecting at least 115,000 people in the UK. The condition usually develops in teenagers and young adults, but can be diagnosed at any age and is equally common in men and women.

How GLP-1 Drugs May Affect Crohn’s Disease and Ulcerative Colitis

GLP-1 receptor agonists support weight loss and metabolic control in people with inflammatory bowel disease, while preclinical studies suggest possible anti-inflammatory effects. Observational studies associate their use with fewer adverse IBD outcomes in some populations, but randomized trials are needed to establish clinical benefits.

Crohn's Disease Diagnosis

Intestinal Mycoplasma and Crohn's Disease

Crohn's Disease Symptoms

What is Crohn's Disease?

History of Crohn's Disease

Crohn's Disease Treatment

Crohn's Disease Complications

Crohn's Disease Cause

Latest Crohn's Disease News and Research

Soft robotic enteroscope offers a new approach to small intestine examination

An innovative robotic device inspired by snake movement could someday help gastroenterologists diagnose and treat inflammatory bowel disease (IBD) and other disorders of the small intestine and remove small polyps while reducing trauma to the organ's delicate tissues.

28 Oct 2026

UK study identifies ways to improve bowel cancer detection in IBD patients

The first UK-wide analysis of bowel screening for patients with inflammatory bowel disease (IBD) has identified opportunities to improve the early detection of cancer.

27 Oct 2026

Antibody patterns may predict inflammatory bowel disease years before diagnosis

A large-scale study, presented today at UEG Week 2026, has identified distinct antibody patterns up to 10 years before the diagnosis of inflammatory bowel disease (IBD), potentially opening new avenues for earlier risk detection and providing insights into future disease course.

19 Oct 2026

New study investigates PFAS exposure and future inflammatory bowel disease

Exposure to per- and polyfluoroalkyl substances (PFAS), often called "forever chemicals," may play a role in the development of inflammatory bowel disease (IBD) years before symptoms appear, according to a new five-year study supported by a $3.3 million National Institutes of Health (NIH) R01 grant to researchers at the Icahn School of Medicine at Mount Sinai.

5 Oct 2026

New multimodal AI model improves breast cancer screening accuracy

Breast cancer screening must balance diagnostic accuracy with workflow throughput. DM remains the traditional cornerstone, but its two-dimensional projection creates tissue-overlap noise, particularly in dense breasts, leading to false positives and obscured lesions.

24 Sep 2026

Military blast exposure associated with long-term health conditions

Exposure to high-level blasts from incoming explosive devices or land mines among military veterans is associated with an increased risk of several conditions such as seizures, neuropathy and stroke years later, according to a study published September 16, 2026, in Neurology, the medical journal of the American Academy of Neurology.

16 Sep 2026

IBD patients with family cancer history more likely to develop colorectal cancer

People with inflammatory bowel disease (IBD) who have several close relatives with colorectal cancer are significantly more likely to develop the disease themselves.

3 Sep 2026

Cellular atlas offers clues to childhood Crohn’s treatment response

Researchers have created a detailed map of childhood Crohn's disease before and after treatment to help understand progression of the disease.

1 Sep 2026

Antifungal medication may reduce inflammatory bowel disease symptoms

A commonly used systemic antifungal medication may help reduce symptoms in a subset of patients with inflammatory bowel disease (IBD) by restoring a healthier gut microbiome, according to a preliminary study by Weill Cornell Medicine investigators.

1 Sep 2026

Polydatin reduces ulcerative colitis by regulating intestinal immune cells

Ulcerative colitis (UC) is a chronic inflammatory bowel disease in which recurrent intestinal inflammation can be difficult to control over the long term.

17 Aug 2026

AI-based "tissue clocks" measure the biological age of human organs

AI-based "tissue clocks" can estimate the biological age of human organs from histological images, researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences and the Ludwig Boltzmann Institute for Network Medicine (LBI-NetMed) at the University of Vienna showed.

14 Aug 2026

AI-augmented analysis sheds new light on Crohn's disease complications

Scientists have combined Artificial Intelligence (AI), genetics and gut microbiome analysis to shed new light on one of the most serious complications of Crohn's disease: intestinal fibrosis, the irreversible scarring of the bowel that often leads to surgery.

12 Aug 2026

Inflammatory bowel disease linked to elevated risk of psychiatric disorders

Patients with inflammatory bowel disease (IBD) face a significantly higher risk of psychiatric disorders starting two to three years before diagnosis and lasting up to a decade after, according to a nationwide study to be published in Clinical Gastroenterology and Hepatology.

5 Aug 2026

3D DNA organization in rare immune cells can explain Crohn's disease risk

A new study co-led by Prof. Valeriya Malysheva, group leader at the VIB-UAntwerp Center for Molecular Neurology, has been published in Nature Genetics.

4 Aug 2026

Australian-first twin study aims to to unlock new insights into immune health

An Australian-first study of twins will seek to find out why two genetically similar people respond differently to infections, diseases and treatments.

4 Aug 2026

New genomic approach links rare immune cells to autoimmune disease risk

Much of how genetic risk leads to disease has remained hidden. In many cases, genetic variants linked to disease do not act on nearby genes along the chromosome.

4 Aug 2026

Global childhood IBD trends reveal unequal progress in diagnosis and survival

An analysis of GBD 2021 estimates across 204 countries and territories found that global deaths from early-onset IBD fell by approximately 71% among children younger than 10 between 1990 and 2021. However, estimated incident and prevalent case numbers rose while the age-standardized incidence rate remained broadly stable, with persistent socioeconomic and regional inequalities.

20 Jul 2026

Mcmaster researchers develop targeted phage therapy for inflammatory bowel disease

A research team at McMaster University has developed a targeted approach to treating inflammatory bowel disease (IBD) using bacteriophages, viruses that infect specific bacteria, to disarm harmful microbes without disrupting the broader gut ecosystem.

8 Jul 2026

Researchers identify key protein balancing gut immunity and inflammation

A protein produced by gut immune cells orchestrates both immune protection against pathogens and immune tolerance of gut bacteria, according to a study led by Weill Cornell Medicine investigators.

7 Jul 2026