Dementia News and Research

Latest Dementia News and Research

New report finds little evidence to support off-label use of atypical antipsychotics

There is little evidence to support the use of atypical antipsychotic drugs for some treatments other than their officially approved purposes, even though many clinicians continue to commonly prescribe these drugs for so-called "off label" uses, according to a new report from the U.S. Department of Health and Human Services' (HHS) Agency for Healthcare Research and Quality.

29 Sep 2011

Congress must not make cuts to crucial government-funded aging research

America's experts on aging are headed for meetings with their senators and representatives to underscore the needs of the country's senior population, spurred by the first-ever Take Action Week organized by The Gerontological Society of America - the nation's largest interdisciplinary organization devoted to the field of aging.

28 Sep 2011

Adamas begins ADS-5102 Phase 2/3 clinical trial in Parkinson's disease

Adamas Pharmaceuticals, Inc., a privately held company, announced today that it has initiated a Phase 2/3 clinical trial of its proprietary investigational drug ADS-5102 (amantadine HCl extended release) for the treatment of levodopa induced dyskinesia (LID) in patients with Parkinson's disease.

28 Sep 2011

Benefits and harms vary among atypical antipsychotics for off-label use

A review of previous studies suggests that even though atypical antipsychotic medications are commonly used for off-label conditions such as behavioral symptoms of dementia, anxiety, and obsessive-compulsive disorder, these medications are effective for only a few off-label conditions, and that the benefits and harms of these medications for these uses vary, according to an article in the September 28 issue of JAMA.

28 Sep 2011

Low vitamin B12 raises risk of dementia in the elderly: Study

According to a latest study the elderly with low levels of vitamin B12 in their blood may be more likely to develop problems with their thinking skills and have more brain shrinkage. The study points to a link between low B12 and early cognitive decline, a condition that often leads to dementia. Previous research has found that those people with high levels of vitamin B12 in their blood have lower levels of an amino acid called homocysteine, which some studies have linked to an increased risk of Alzheimer's disease, memory loss, and stroke.

27 Sep 2011

NYU Langone to lead NVVLS on long-term effects of PTSD

NYU Langone Medical Center announced that Charles R. Marmar, MD, the Lucius N. Littauer Professor of Psychiatry and chair of the Department of Psychiatry, was selected to lead the clinical evaluation component of a national survey — the National Vietnam Veterans Longitudinal Study (NVVLS) — on the long-term effects of combat-related post-traumatic stress disorder (PTSD) and other related health conditions on Vietnam veterans.

27 Sep 2011

NINDS award to fund studies of Arizonans with Parkinson's disease

The National Institute of Neurological Disorders and Stroke (NINDS) announced this week an $8 million, five-year grant to support a "National Brain and Tissue Resource for Parkinson's Disease and Related Disorders", awarded to Banner Sun Health Research Institute (BSHRI) and Mayo Clinic Arizona.

26 Sep 2011

Dementia patients have poor outcomes in hospital

If you have dementia and need to be admitted to hospital to be treated for other illnesses or injuries, your prospects for recovery are substantially worse than for other patients, research has found.

22 Sep 2011

Wnt signaling pathway plays an important role in early-onset dementia

No cure exists for frontotemporal dementia, which strikes between the ages of 40 and 64 and accounts for at least one in four cases of early-onset dementia. Caused by the death of cells in the front and sides of the brain, the disease can lead to dramatic changes in a patient's personality and behavior, including the loss of the ability to communicate.

22 Sep 2011

Humour therapy as effective as antipsychotic drugs in managing agitation in dementia patients

Humour therapy is as effective as widely used antipsychotic drugs in managing agitation in patients with dementia - and avoids serious drug side effects, a new study shows.

22 Sep 2011

Families help identify new gene for motor neuron disease

Families suffering from a history of motor neuron disease have helped an international scientific team locate a new gene linked to the incurable disease.

22 Sep 2011

Researchers identify common genetic mutation for ALS, frontotemporal dementia

Frontotemporal dementia and amyotrophic lateral sclerosis, also known as Lou Gehrig's disease -- two fatal neurodegenerative disease with distinct but sometimes overlapping symptoms -- are triggered by a common mutation in many cases, according to researchers who say they have identified the mutated gene.

22 Sep 2011

First epidemiological study on the prevention of Alzheimer's disease

Researchers at the Douglas Mental Health University Institute, in Montreal, Quebec, are about to launch the first epidemiological study on the prevention of Alzheimer's disease.

22 Sep 2011

Scientists discover new genetic mutation for amyotrophic lateral sclerosis

A team led by scientists from Johns Hopkins and the National Institutes of Health has discovered a new genetic mutation for amyotrophic lateral sclerosis (ALS) and a related disease called frontotemporal dementia (FTD) that appears to account for more than a third of all inherited cases of these diseases.

22 Sep 2011

Saladax, Bristol-Myers Squibb expand Alzheimer's diagnostic assays agreement

Bristol-Myers Squibb Company and Saladax Biomedical, Inc., announced today they have expanded their multi-year agreement covering the development and commercialization of diagnostic assays for the early detection of Alzheimer's disease to include Ortho-Clinical Diagnostics, Inc.

21 Sep 2011

UNC sports medicine researcher receives 2011 MacArthur Fellowship for concussion study

University of North Carolina at Chapel Hill sports medicine researcher Kevin Guskiewicz, one of the country's leading experts on concussions, has been named a 2011 MacArthur Fellow.

21 Sep 2011

Tackling Alzheimer’s and dementia

The latest research into the prevention and treatment of dementia and Alzheimer’s is the focus of a major conference in Sydney this week.

20 Sep 2011

Diabetes and dementia, connection found

A new study revealed that people with diabetes may be at an increased risk of developing dementia. Scientists have suspected the link between the two diseases for several years, but several experts say this latest study highlights how treating preventable diseases like diabetes and obesity may be useful in preventing the onset of dementia.

20 Sep 2011

People with diabetes more likely to develop dementia

People with diabetes appear to be at a significantly increased risk of developing dementia, according to a study published in the September 20, 2011, print issue of Neurology, the medical journal of the American Academy of Neurology.

20 Sep 2011

Common misconceptions about Alzheimer's disease

Alzheimer's disease, the most common form of dementia, continues to be an ongoing battle for millions of Americans. With an estimated 5.4 million Americans living with the disease and an annual cost of $183 billion, Dr. Gustavo C. Roman, director of the Nantz National Alzheimer Center at the Methodist Neurological Institute, addresses some common misconceptions about this devastating disease.

20 Sep 2011