Gene News and Research

Latest Gene News and Research

NIH to start initial human testing of investigational Ebola vaccine next week

Initial human testing of an investigational vaccine to prevent Ebola virus disease will begin next week by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

29 Aug 2014

Changes in ADNP gene may provide further insight into causes of autism

A new study from Bradley Hospital has identified a genetic change in a recently identified autism-associated gene, which may provide further insight into the causes of autism. The study, now published online in the Journal of Medical Genetics, presents findings that likely represent a definitive clinical marker for some patients' developmental disabilities.

29 Aug 2014

Minnesota researchers develop animal research model for FSHD

Researchers at the University of Minnesota have developed an animal research model for facioscapulohumeral muscular dystrophy (FSHD) to be used for muscle regeneration research as well as studies of the effectiveness of potential therapies for FSHD.

29 Aug 2014

BloodCenter's Erythroid Chimerism test available to monitor transplanted SCD patients

BloodCenter of Wisconsin's Diagnostic Laboratories today announced the availability of an innovative Erythroid Chimerism test to monitor erythroid lineage chimerism in patients with sickle cell disease (SCD) following allogeneic bone marrow transplantation.

28 Aug 2014

Amgen seeks FDA approval for evolocumab to treat patients with high cholesterol

Amgen today announced the submission of a Biologics License Application (BLA) to the U.S. Food and Drug Administration for evolocumab seeking approval for the treatment of high cholesterol.

28 Aug 2014

Mutant allele frequency predicts lung cancer TKI response

Tyrosine kinase inhibitor sensitivity may be predicted by the frequency of a point mutation in the epidermal growth factor receptor gene, suggests a study of Japanese patients with advanced lung adenocarcinoma.

28 Aug 2014

Gene variants linked to overactive bladder and prolapse in women

A systematic review and meta-analysis of genetic association studies reveals a number of genetic variations associated with overactive bladder and pelvic organ prolapse in women.

28 Aug 2014

High PD-L1 expression linked to reduced survival in NSCLC

Overexpression of programmed death-ligand 1 is independently associated with the presence of epidermal growth factor receptor gene mutations and poor prognosis in patients with non-small-cell lung cancer, Japanese researchers report.

28 Aug 2014

Scientists solve mystery of why specific signaling pathway can be linked with alcohol dependence

Scientists at The Scripps Research Institute (TSRI) have solved the mystery of why a specific signaling pathway can be associated with alcohol dependence.

28 Aug 2014

Scientists alter emotional associations of specific memories

By manipulating neural circuits in the brain of mice, scientists have altered the emotional associations of specific memories.

28 Aug 2014

Research report: Orphan Diseases Partnering Terms and Agreements

The Orphan Diseases Partnering Terms and Agreements report provides an understanding and access to the orphan diseases partnering deals and agreements entered into by the worlds leading healthcare companies.

28 Aug 2014

Report on Co-development Terms & Agreements in Pharma, Biotech and Diagnostics

The Co-development Terms and Agreements in Pharma, Biotech and Diagnostics report provides comprehensive understanding and unprecedented access to the co-development deals and agreements entered into by the worlds leading life science companies.

28 Aug 2014

Study: Many HIV infected African-Americans may not be receiving effective doses of maraviroc drug

Many African-Americans may not be getting effective doses of the HIV drug maraviroc, a new study from Johns Hopkins suggests. The initial dosing studies, completed before the drug was licensed in 2007, included mostly European-Americans, who generally lack a protein that is key to removing maraviroc from the body.

28 Aug 2014

Advanced statistical approach evaluates gene-environmental interactions that contribute to disease

Dartmouth cancer researchers developed and tested an advanced statistical model to evaluate the genetic and environmental interactions that contribute to disease as published yesterday in Human Genetics.

28 Aug 2014

Researchers help to gain greater insight into biological clock that sets pace for daily life

Casey Diekman, assistant professor of mathematical sciences at New Jersey Institute of Technology (NJIT), is helping to gain greater insight into the biological clock that sets the pace for daily life.

27 Aug 2014

Versatile nanoparticles offer wide variety of diagnostic and therapeutic applications

Kit Lam and colleagues from UC Davis and other institutions have created dynamic nanoparticles (NPs) that could provide an arsenal of applications to diagnose and treat cancer.

27 Aug 2014

Spanish scientists explore genetic basis of familial extreme longevity

In a recent report in Aging Cell, a multidisciplinary team of Spanish scientists, led by Tim Cash and Manuel Serrano at the Spanish National Cancer Research Centre, identify rare variants in the APOB gene in several families where exceptional longevity (>100 years of age) appears to cluster.

26 Aug 2014

Repurposing anti-depressant medication to target new pathway may help combat medulloblastoma

An international research team reports in Nature Medicine a novel molecular pathway that causes an aggressive form of medulloblastoma, and suggests repurposing an anti-depressant medication to target the new pathway may help combat one of the most common brain cancers in children.

26 Aug 2014

Female rats whose great grandparents exposed to toxins become more vulnerable to stress

Scientists have known that toxic effects of substances known as endocrine disrupting chemicals (EDCs), found in both natural and human-made materials, can pass from one generation to the next, but new research shows that females with ancestral exposure to EDC may show especially adverse reactions to stress.

26 Aug 2014

Researchers find why certain glioblastomas become drug resistance

Researchers at the University of California, San Diego School of Medicine have found one of the keys to why certain glioblastomas - the primary form of a deadly brain cancer - are resistant to drug therapy.

26 Aug 2014

Gene News and Research

Latest Gene News and Research

NIH to start initial human testing of investigational Ebola vaccine next week

Changes in ADNP gene may provide further insight into causes of autism

Minnesota researchers develop animal research model for FSHD

BloodCenter's Erythroid Chimerism test available to monitor transplanted SCD patients

Amgen seeks FDA approval for evolocumab to treat patients with high cholesterol

Mutant allele frequency predicts lung cancer TKI response

Gene variants linked to overactive bladder and prolapse in women

High PD-L1 expression linked to reduced survival in NSCLC

Scientists solve mystery of why specific signaling pathway can be linked with alcohol dependence

Scientists alter emotional associations of specific memories

Research report: Orphan Diseases Partnering Terms and Agreements

Report on Co-development Terms & Agreements in Pharma, Biotech and Diagnostics

Study: Many HIV infected African-Americans may not be receiving effective doses of maraviroc drug

Advanced statistical approach evaluates gene-environmental interactions that contribute to disease

Researchers help to gain greater insight into biological clock that sets pace for daily life

Versatile nanoparticles offer wide variety of diagnostic and therapeutic applications

Spanish scientists explore genetic basis of familial extreme longevity

Repurposing anti-depressant medication to target new pathway may help combat medulloblastoma

Female rats whose great grandparents exposed to toxins become more vulnerable to stress

Researchers find why certain glioblastomas become drug resistance

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

How Pulp Fixin Is Turning Paper into High-Performance Sustainable Labware

A new method to measure intracellular water in biological systems

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