Gene News and Research

Latest Gene News and Research

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Currently used Food and Drug Administration-approved transplant drugs - with the addition of an also already FDA-approved complement inhibitor - are the optimal immunosuppression regimen for pig-to-human kidney transplants, according to a landmark discovery by University of Alabama at Birmingham investigators.

25 Jan 2024

Unbiased assessment of vamorolone for treating Duchenne muscular dystrophy

The drug vamorolone (Agamree) has been hailed as a promising new drug to treat Duchenne muscular dystrophy (DMD).

25 Jan 2024

Study addresses knowledge gap of clinical features and outcomes of Black patients with melanoma

Researchers identified patient- and tumor-level melanoma features in black individuals.

25 Jan 2024

Study shows effectiveness of gene therapy in treating congenital deafness

A new study co-led by investigators from Mass Eye and Ear, a member of Mass General Brigham, demonstrated the effectiveness of a gene therapy towards restoring hearing function for children suffering from hereditary deafness.

24 Jan 2024

Penn analysis shows low risk of secondary cancers following CAR T cell therapy

The development of any type of second cancer following CAR T cell therapy is a rare occurrence, as found in an analysis of more than 400 patients treated at Penn Medicine, researchers from the Perelman School of Medicine at the University of Pennsylvania reported today in Nature Medicine.

24 Jan 2024

Novel macrolide- DEL-1 axis helps in bone regeneration and new bone formation

Periodontitis is characterized by the loss of teeth resulting from inflammation of gums due to bacterial infections.

24 Jan 2024

Mayo Clinic unveils "secret gene" key to reversing heart failure in some patients

Mayo Clinic researchers studying the genetics of people who had recently developed dilated cardiomyopathy, one of the most common causes of heart failure, have found a particular gene to target for developing future drug therapy treatments.

24 Jan 2024

Mutations found in skin cancers could be harnessed to mend broken hearts

Biomedical engineers at Duke University have demonstrated that one of the most dangerous mutations found in skin cancers might moonlight as a pathway to mending a broken heart.

24 Jan 2024

Ancient DNA reveals syphilis-like disease in pre-Columbian America

Researchers at the Universities of Basel and Zurich have discovered the genetic material of the pathogen Treponema pallidum in the bones of people who died in Brazil 2,000 years ago.

24 Jan 2024

Researchers uncover a gene that causes heart defects in Down syndrome

Researchers at the Francis Crick Institute and UCL have identified a gene that causes heart defects in Down syndrome, a condition that results from an additional copy of chromosome 21.

24 Jan 2024

mRNA therapy revives p53 to combat ovarian tumors

Ovarian cancer is often very aggressive and responds poorly to the therapies currently available. A recent study by Goethe University Frankfurt and University Hospital Frankfurt offers hope that this could change in the medium term.

24 Jan 2024

RNA Therapies in Liver Disease: Insights from Ochre Bio's CEO

In this interview, we speak with Jack O'Meara, co-founder and CEO of Ochre Bio, a pioneering force in liver disease treatment. O'Meara shares insights into Ochre Bio's innovative RNA therapies, their approach to tackling liver disease, and the company's vision for the future.

24 Jan 2024

Core Biogenesis and Nucleus Biologics announce strategic collaboration for manufacturing and distribution of cost effective and sustainable recombinant proteins

In a joint effort to provide lower cost and more defined reagents and media to the cell and gene therapy market, Nucleus Biologics, The Cell Performance Company™, a leading provider of custom cell culture media solutions for the cell and gene therapy industry, has signed a manufacturing, distribution, and collaboration agreement with Core Biogenesis, an innovator in the field of recombinant human proteins expressed in plants.

From Nucleus Biologics 24 Jan 2024

Prepared for the next virus pandemic: The APPEAL project

In collaboration with 12 partners from 6 countries, MatTek is establishing the Antivirus Pandemic Preparedness EuropeAn pLatform (APPEAL), a European research initiative aimed at enhancing preparedness for future pandemics.

From MatTek Corporation 24 Jan 2024

Link between long-term hyperglycemia and upper-limb musculoskeletal conditions revealed

Study demonstrates that long-term hyperglycemia significantly increases the risk of upper-limb musculoskeletal conditions, while BMI influences the risk of carpal tunnel syndrome and Dupuytren's disease differently.

23 Jan 2024

New workflow identifies shared cancer targets, advancing immunotherapy

Researchers developed the Splicing Neo Antigen Finder (SNAF) workflow, integrating deep learning to identify shared immunogenic neoantigens in cancers, offering new targets for cancer immunotherapy, particularly in melanoma and ovarian cancer.

23 Jan 2024

LTBR identified as potential target for cancer immunotherapy and marker of poor prognosis

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 1, entitled, "Systematic analysis of the prognostic value and immunological function of LTBR in human cancer."

23 Jan 2024

Gene News and Research

Latest Gene News and Research

Study establishes the ideal immunosuppression regimen for pig-to-human kidney xenotransplantation

Unbiased assessment of vamorolone for treating Duchenne muscular dystrophy

Study addresses knowledge gap of clinical features and outcomes of Black patients with melanoma

Study shows effectiveness of gene therapy in treating congenital deafness

Penn analysis shows low risk of secondary cancers following CAR T cell therapy

Novel macrolide- DEL-1 axis helps in bone regeneration and new bone formation

Mayo Clinic unveils "secret gene" key to reversing heart failure in some patients

Mutations found in skin cancers could be harnessed to mend broken hearts

Ancient DNA reveals syphilis-like disease in pre-Columbian America

Researchers uncover a gene that causes heart defects in Down syndrome

mRNA therapy revives p53 to combat ovarian tumors

RNA Therapies in Liver Disease: Insights from Ochre Bio's CEO

Core Biogenesis and Nucleus Biologics announce strategic collaboration for manufacturing and distribution of cost effective and sustainable recombinant proteins

Prepared for the next virus pandemic: The APPEAL project

Link between long-term hyperglycemia and upper-limb musculoskeletal conditions revealed

New workflow identifies shared cancer targets, advancing immunotherapy

LTBR identified as potential target for cancer immunotherapy and marker of poor prognosis

New technique helps track the brain's "off switches"

New atlas reveals a slew of cellular and molecular interactions that drive ovulation

SynNeurGe: A new biological classification system for Parkinson's disease research

Industry Focus: Cell & Gene Therapy eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research