Gene News and Research

Latest Gene News and Research

Low-risk DCIS patients may safely skip radiotherapy after surgery, study finds

Patients with low-risk ductal carcinoma in situ (DCIS) who skipped adjuvant radiotherapy after breast-conserving surgery had comparable five-year outcomes to those with high-risk DCIS who received adjuvant radiotherapy, according to results from the E4112 clinical trial presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

8 Dec 2023

Study identifies targetable fusion RNAs in breast cancer

Comprehensive profiling of fusion RNAs present in a large cohort of metastatic breast tumors revealed unique fusion mutations that may be therapeutically targetable, according to results presented at the San Antonio Breast Cancer Symposium, held December 5-9, 2023.

8 Dec 2023

Study offers new hope for heart repair and regeneration with reduced mitochondrial activity

USF Health Heart Institute doctors are upbeat about cardiac regeneration. But when those batteries – heart muscle cells called cardiomyocytes − short circuit and die, the damage can be devastating.

8 Dec 2023

Many patients may not benefit from gene-editing treatments for sickle cell disease

Federal approval of a breakthrough gene-editing technology that treats the pain and debilitating effects of sickle cell disease is cause for celebration among a community with few options for relief.

8 Dec 2023

Study sheds light on the molecular workings at play when oxygen exceeds normal levels

It only takes holding your breath for slightly too long to understand that too little oxygen is bad for you. But can you also have too much? Indeed, breathing air with a higher oxygen level than your body needs can cause health problems or even death.

8 Dec 2023

Scientists decode key factor in T cell lymphoma growth, paving way for new treatments

A team from the Technical University of Munich (TUM) has decoded the factor that makes T cell lymphomas grow comparatively rapidly: A missing "emergency shut-off switch" results in the lymphomas processing particularly large amounts of sugar and triggers other processes as well.

8 Dec 2023

Key gene linked to male bias in autism, Tourette's, and ADHD uncovered

Sex bias in attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and Tourette syndrome (TS).

8 Dec 2023

Groundbreaking 'Gnocchi' map reveals hidden secrets of the human genome

Study presents a genome-wide map, "Gnocchi," constructed from 76,156 human genomes, revealing that non-coding regions rich in regulatory elements are crucial in understanding human traits and diseases.

7 Dec 2023

Is your body out of sync? Study finds organs age at varying rates

Research uncovers that human organs age at varying rates, with some showing accelerated aging compared to chronological age, significantly impacting overall health and disease risk. The study used advanced blood plasma proteomics to analyze organ-specific aging in nearly 5,700 adults, linking it to increased risks of heart failure and Alzheimer's disease.

7 Dec 2023

Flaxseed lignans found to influence gut microbiome and breast cancer risk

A new study demonstrates that the human gut microbiome may be a factor in breast health. Lifestyle and diet have long been known to affect human health.

7 Dec 2023

Liver trigger holds the key to boosting gene therapy success

Indiana University School of Medicine researchers have uncovered vital insights regarding a liver trigger that blocks an undesired immune response from gene therapy, surprisingly resulting in the activation of specific immune cells, despite the liver's typical role in suppressing immune responses.

7 Dec 2023

Researchers discover how bexmarilimab activates immune cells against tumors

Researchers at the University of Turku, Finland, have uncovered how the new bexmarilimab therapy alters the function of immune cells so that they can infiltrate the tumor in cancer patients who do not respond to any other current therapies.

7 Dec 2023

Novel mechanism leads to motor neuron degeneration in spinal muscular atrophy

The lab of Yongchao C. Ma, PhD, at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago uncovered a novel mechanism that leads to motor neuron degeneration in spinal muscular atrophy (SMA).

7 Dec 2023

Breakthrough discovery paves the way for new methods to detect and treat leukemia

Researchers led by François Fuks - Laboratory of Cancer Epigenetics, ULB Faculty of Medicine, ULB Cancer Research Center and Jules Bordet Institute, H.U.B. - have made a major breakthrough in the understanding and treatment of leukemia.

7 Dec 2023

Study finds link between epimutations in BRCA1 gene and triple-negative breast cancer risk

Research reveals that around 20 per cent of all cases of the most severe form of breast cancer may arise from the small group of normal tissue cells carrying an epimutation of a specific gene.

7 Dec 2023

Associations between low-inflammatory diets and diabetes risk

Associations between a low-inflammatory diet and type 2 diabetes (T2D) risk.

7 Dec 2023

From LED screens to genes: The effects of blue light on aging and m6A methylation in fruit flies

Researchers created Drosophila models using multi-omics profiles to elucidate the biological mechanisms and effects of everyday low-intensity blue light exposure (BLE).

7 Dec 2023

ANU research uncovers protein's role in autoimmune disease and cancer

A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases such as irritable bowel disease (IBS), type 1 diabetes, eczema and other chronic disorders, new research from The Australian National University (ANU) has found.

6 Dec 2023

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Pancreatic cancer is one of the deadliest cancers - only about one in eight patients survives five years after diagnosis.

6 Dec 2023

Evonetix Announces Agreement for Revolutionary Gene Synthesis Platform With Analog Devices

EVONETIX LTD (‘Evonetix’), the company developing semiconductor scale technology to improve access to gene synthesis, today announces the signing of a joint development agreement and commercial supply agreement with Analog Devices, Inc. (ADI), a global semiconductor leader.

6 Dec 2023

Gene News and Research

Latest Gene News and Research

Low-risk DCIS patients may safely skip radiotherapy after surgery, study finds

Study identifies targetable fusion RNAs in breast cancer

Study offers new hope for heart repair and regeneration with reduced mitochondrial activity

Many patients may not benefit from gene-editing treatments for sickle cell disease

Study sheds light on the molecular workings at play when oxygen exceeds normal levels

Scientists decode key factor in T cell lymphoma growth, paving way for new treatments

Key gene linked to male bias in autism, Tourette's, and ADHD uncovered

Groundbreaking 'Gnocchi' map reveals hidden secrets of the human genome

Is your body out of sync? Study finds organs age at varying rates

Flaxseed lignans found to influence gut microbiome and breast cancer risk

Liver trigger holds the key to boosting gene therapy success

Researchers discover how bexmarilimab activates immune cells against tumors

Novel mechanism leads to motor neuron degeneration in spinal muscular atrophy

Breakthrough discovery paves the way for new methods to detect and treat leukemia

Study finds link between epimutations in BRCA1 gene and triple-negative breast cancer risk

Associations between low-inflammatory diets and diabetes risk

From LED screens to genes: The effects of blue light on aging and m6A methylation in fruit flies

ANU research uncovers protein's role in autoimmune disease and cancer

HDAC inhibitors may offer new strategy for reversing fibrotic wall around pancreatic tumors

Evonetix Announces Agreement for Revolutionary Gene Synthesis Platform With Analog Devices

Industry Focus: Cell & Gene Therapy eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research