Gene News and Research

Latest Gene News and Research

Breast cancer and MEN1: exploring the connection

Researchers evaluated the role of Multiple Endocrine Neoplasia 1 (MEN1) messenger ribonucleic acid (mRNA) in breast cancer

17 Jul 2023

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes

Researchers develop and characterize a highly specific EpiEditing system using catalytically inactivated catalytically inactivated Cas9.

17 Jul 2023

Innovative mixed reality training platform to be developed for pharmaceutical companies and healthcare

UK immersive technology company FourPlus, along with collaborators Holosphere and the Cell and Gene Therapy Catapult, have been awarded funding from Innovate UK to create and test a mixed reality training platform that enables customised training delivery for pharmaceutical companies and healthcare.

17 Jul 2023

Stable nanoparticles train the immune system to fight cancer

Over the past decade, researchers have sought more effective and enduring cancer treatments. Among the wide variety of immunotherapies, Stimulator of Interfron Genes activation (STING agonism) has emerged as a particularly promising approach that harnesses a patient’s immune system to combat tumors throughout the body.

17 Jul 2023

Aerobic glycolysis essential for eye development in mammals, study finds

Aerobic glycolysis, the process by which cells transform glucose into lactate, is key for eye development in mammals, according to a new Northwestern Medicine study published in Nature Communications.

14 Jul 2023

m6A modification as a potential therapeutic target for autoimmune diseases

N6-methyladenosine (m6A) is the most extensive studied RNA modification across various species, and the important effect of m6A modification in immune system has been revealed in distinct contexts, including mRNA metabolism, cell differentiation, proliferation and response to stimulation.

14 Jul 2023

Insilico Medicine and MIKADO team up to find new treatments for cystinosis

A team led by researchers at the Mechanisms of Inherited Kidney Disorders (MIKADO) group at the University of Zurich (Zurich, Switzerland) has used Insilico Medicine's generative artificial intelligence (AI) target discovery engine, PandaOmics, to identify actionable drug targets for the lysosomal storage disease cystinosis and to validate them in preclinical models of the disease.

14 Jul 2023

The hidden factors of resistance: how pathogen diversity drives antibiotic response

Researchers aimed to understand the role of within-host microbial diversity on antimicrobial resistance.

14 Jul 2023

New study reveals mast cells' surprising role in allergy-related avoidance behavior

Researchers showed that mast cells and IgE are the key orchestrators of antigen-specific avoidance.

14 Jul 2023

Study suggests anxiety increases the risk of subsequent cognitive progression in non-dementia elderly

Researchers investigate the effects of anxiety on cognitive degeneration in non-dementia elderly.

14 Jul 2023

Macrophages may play a major role in the development of atrial fibrillation

Current treatments for atrial fibrillation (AFib), a common heart condition characterized by fast and irregular beats that can lead to stroke and heart failure, have multiple side effects and are ineffective for preventing AFib recurrence.

13 Jul 2023

Using CRISPR gene-editing system to build a more sustainable forest

Researchers at North Carolina State University used a CRISPR gene-editing system to breed poplar trees with reduced levels of lignin, the major barrier to sustainable production of wood fibers, while improving their wood properties.

13 Jul 2023

Study sheds light on how COVID-19 infection may lead to late pregnancy complications

The Hong Kong University of Science and Technology (HKUST) and The Chinese University of Hong Kong (CUHK) today unveiled ground-breaking research that sheds light on how COVID-19 infection may lead to late pregnancy complications.

13 Jul 2023

British neuroscientist wins Hartwig Piepenbrock-DZNE Prize for contributions to dementia research

This year's "Hartwig Piepenbrock-DZNE Prize", endowed with 60,000 euros, goes to the British neuroscientist Alison Goate, DPhil. The award recognizes her outstanding contributions to research into Alzheimer's disease and frontotemporal dementia.

13 Jul 2023

Detection of antibiotic resistance genes in clinical samples through bioinformatic approaches

Study explored the utility of metagenomic next-generation sequencing alignment methods to identify bacterial populations with antibiotic resistance.

13 Jul 2023

New study reveals how lung tumors develop drug resistance

Cancer therapies that target specific genetic abnormalities in tumors have revolutionized treatment possibilities over the past two decades.

13 Jul 2023

New precision medicine trial shows promise for treating rare brain tumors

Papillary craniopharyngiomas (PCPs) are a rare type of brain tumor that cause substantial morbidity for patients.

13 Jul 2023

IL-9 identified as contributor to viral spread and airway inflammation in COVID-19

Researchers used a K18-hACE2 transgenic (ACE2.Tg) mouse model to demonstrate that interleukin-9 (IL-9).

13 Jul 2023

UCLA researchers confirm mutations that predispose patients to rare kidney cancer syndrome

Researchers at the UCLA Jonsson Comprehensive Cancer Center have confirmed that a large number of genetic variants of unknown significance are in fact verified mutations that predispose patients to a rare hereditary syndrome that increases the risk of kidney cancer.

13 Jul 2023

Pembrolizumab combination therapies effective for advanced NSCLC, study shows

While pembrolizumab is an approved treatment for patients with stage III non-small cell lung cancer (NSCLC), only some patients respond to this therapy. Treatment failure, researchers say, is often caused by differences in the tumor microenvironment.

12 Jul 2023

Gene News and Research

Latest Gene News and Research

Breast cancer and MEN1: exploring the connection

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes

Innovative mixed reality training platform to be developed for pharmaceutical companies and healthcare

Stable nanoparticles train the immune system to fight cancer

Aerobic glycolysis essential for eye development in mammals, study finds

m6A modification as a potential therapeutic target for autoimmune diseases

Insilico Medicine and MIKADO team up to find new treatments for cystinosis

The hidden factors of resistance: how pathogen diversity drives antibiotic response

New study reveals mast cells' surprising role in allergy-related avoidance behavior

Study suggests anxiety increases the risk of subsequent cognitive progression in non-dementia elderly

Macrophages may play a major role in the development of atrial fibrillation

Using CRISPR gene-editing system to build a more sustainable forest

Study sheds light on how COVID-19 infection may lead to late pregnancy complications

British neuroscientist wins Hartwig Piepenbrock-DZNE Prize for contributions to dementia research

Detection of antibiotic resistance genes in clinical samples through bioinformatic approaches

New study reveals how lung tumors develop drug resistance

New precision medicine trial shows promise for treating rare brain tumors

IL-9 identified as contributor to viral spread and airway inflammation in COVID-19

UCLA researchers confirm mutations that predispose patients to rare kidney cancer syndrome

Pembrolizumab combination therapies effective for advanced NSCLC, study shows

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