Gene News and Research

Latest Gene News and Research

Analyzing the role of ACSL4 in quadruple negative breast cancer

A new review paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "ACSL4: biomarker, mediator and target in quadruple negative breast cancer."

15 Jun 2023

Detailed 3D images of the synapse offer precise geometry of interactions between individual cells

Scientists have created one of the most detailed 3D images of the synapse, the important juncture where neurons communicate with each other through an exchange of chemical signals. These nanometer scale models will help scientists better understand and study neurodegenerative diseases such as Huntington's disease and schizophrenia.

15 Jun 2023

New method of insulin delivery lowers the risk of hypoglycemia compared to current diabetes treatments

Insulin production has, for the last 50 or so years, come with some risks to the patient. Even so, the medication is lifesaving for the estimated 537 million adults living with diabetes worldwide, with that number expected to grow.

15 Jun 2023

Scientists identify major mechanism behind the transition between chronic and acute bacterial infections

People with weakened immune systems are at constant risk of infection. Pseudomonas aeruginosa, a common environmental bacterium, can colonize different body parts, such as the lungs, leading to persistent, chronic infections that can last a lifetime – a common occurrence in people with cystic fibrosis.

14 Jun 2023

Strongest genetic risk factors for Viking disease are inherited from Neanderthals

Many men in northern Europe over the age of 60 suffer from the so-called Viking disease, which means that the fingers lock in a bent position.

14 Jun 2023

Mutations that lead to intracranial aneurysms discovered

Researchers at the RIKEN Center for Brain Science (CBS) in Japan have discovered a set of related mutations that lead to intracranial aneurysms - weakened blood vessels in the brain that can burst at any time.

14 Jun 2023

Inflammation regulating gene also plays a key role in maintaining normal blood-sugar levels, study shows

A study led by researchers at the Garvan Institute of Medical Research shows for the first time how a gene called RELA, known to regulate inflammation, also plays an essential role in maintaining normal blood-sugar levels.

14 Jun 2023

Understanding the developmental link: vitamin D's role in metabolic disease risk

Study showed that transplanting fetal hematopoietic stem cells exposed to vitamin D deficiency induces diabetes.

14 Jun 2023

Scientists show how pregnancy induces progressive changes in the maternal immune system

We have a good understanding of how a woman's external features can change during pregnancy, but scientists know surprisingly little about what biological changes occur internally.

13 Jun 2023

Retooling the cell's polypeptide manufacturing plants to generate polymer chains

Synthetic biologists have become increasingly creative in engineering yeast or bacteria to churn out useful chemicals - from fuels to fabrics and drugs - beyond the normal repertoire of microbes.

13 Jun 2023

Regulatory connection between DREAM and cellular senescence may play a potential role in aging process

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Key elements of cellular senescence involve transcriptional repression of mitotic and DNA repair genes through the p53-p16/RB-E2F-DREAM complex."

13 Jun 2023

Heat-damaged DNA in food may contribute to genetic risks

Researchers have newly discovered a surprising and potentially significant reason why eating foods frequently cooked at high temperatures, such as red meat and deep-fried fare, elevates cancer risk. The alleged culprit: DNA within the food that's been damaged by the cooking process.

13 Jun 2023

New process for creating a “meta-cell overcomes the challenges of studying single-cell secrets

University of California, Irvine neuroscientists probing the gene changes behind Alzheimer's disease have developed a process of making a "meta-cell" that overcomes the challenges of studying a single cell.

13 Jun 2023

Immune resilience promotes longevity and resistance to infections

Researchers from The University of Texas Health Science Center at San Antonio, working with collaborators in five countries, today revealed that the capacity to resist or recover from infections and other sources of inflammatory stress - called "immune resilience" - differs widely among individuals.

13 Jun 2023

10 postdoctoral fellows from Latin America receive Pew funding for biomedical research

The Pew Charitable Trusts today announced the 2023 class members of the Pew Latin American Fellows Program in the Biomedical Sciences.

13 Jun 2023

DYRK1A gene may dictate susceptibility to multiple highly pathogenic coronaviruses

Entry of the SARS-CoV-2 virus into human tissues depends on the activity of a host gene that regulates production of a key viral receptor, according to a study publishing June 13th in the open access journal PLOS Biology by Madison Strine and Craig Wilen of Yale University, US, and colleagues.

13 Jun 2023

Tracing the ancestry of hybrids using a new method

If you've ever kept a garden, you're probably familiar with hybrids, from disease-resistant tomatoes to Stargazer lilies.

13 Jun 2023

Automated liquid biopsy test predicts early disease progression, survival among patients with metastatic breast cancer

A novel, automated liquid biopsy test in development by researchers at the Johns Hopkins Kimmel Cancer Center can be used to predict early disease progression and potential survival among patients with metastatic breast cancer in as little as one month after starting treatment, according to a recent study.

13 Jun 2023

ACMG publishes updated recommendations for CFTR carrier screening

The American College of Medical Genetics and Genomics (ACMG) has released updated recommendations for CFTR carrier screening –Updated recommendations for CFTR carrier screening: A position statement of the American College of Medical Genetics and Genomics.

13 Jun 2023

Charles River Laboratories Launches Off-the-Shelf Lentiviral Vector Packaging Plasmids

Charles River Laboratories International, Inc. (NYSE: CRL) today announced the launch of its off-the-shelf lentiviral vector (LVV) packaging plasmids, providing a streamlined solution to the challenges associated with plasmid sourcing in cell and gene therapies.

From Charles Rivers Laboratories Cell and Gene Therapy 13 Jun 2023

Gene News and Research

Latest Gene News and Research

Analyzing the role of ACSL4 in quadruple negative breast cancer

Detailed 3D images of the synapse offer precise geometry of interactions between individual cells

New method of insulin delivery lowers the risk of hypoglycemia compared to current diabetes treatments

Scientists identify major mechanism behind the transition between chronic and acute bacterial infections

Strongest genetic risk factors for Viking disease are inherited from Neanderthals

Mutations that lead to intracranial aneurysms discovered

Inflammation regulating gene also plays a key role in maintaining normal blood-sugar levels, study shows

Understanding the developmental link: vitamin D's role in metabolic disease risk

Scientists show how pregnancy induces progressive changes in the maternal immune system

Retooling the cell's polypeptide manufacturing plants to generate polymer chains

Regulatory connection between DREAM and cellular senescence may play a potential role in aging process

Heat-damaged DNA in food may contribute to genetic risks

New process for creating a “meta-cell overcomes the challenges of studying single-cell secrets

Immune resilience promotes longevity and resistance to infections

10 postdoctoral fellows from Latin America receive Pew funding for biomedical research

DYRK1A gene may dictate susceptibility to multiple highly pathogenic coronaviruses

Tracing the ancestry of hybrids using a new method

Automated liquid biopsy test predicts early disease progression, survival among patients with metastatic breast cancer

ACMG publishes updated recommendations for CFTR carrier screening

Charles River Laboratories Launches Off-the-Shelf Lentiviral Vector Packaging Plasmids

eBook: Using iPSCs models for human disease research and drug discovery eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting