Gene News and Research

Latest Gene News and Research

Study sheds light on how cold temperatures affect appetite

Neuroscientists at Scripps Research have identified brain circuits that make mammals want to eat more when they are exposed to cold temperatures.

16 Aug 2023

Pig kidney xenotransplantation continues to function well after 32 days

Surgeons at NYU Langone Health have transplanted a genetically engineered pig kidney that continues to function well after 32 days in a man declared dead by neurologic criteria and maintained with a beating heart on ventilator support.

16 Aug 2023

Long DNA molecules reveal new scar types in HR-deficient cancers

DNA can be damaged by toxins, radiation, or even normal cell division, but human cells must continually fix DNA breaks to survive.

16 Aug 2023

Sulfate groups on complex sugar molecules affect brain plasticity

Can you recognize someone you haven't seen in years, but forget what you had for breakfast yesterday? Our brains constantly rearrange their circuitry to remember familiar faces or learn new skills, but the molecular basis of this process isn't well understood.

16 Aug 2023

Scientist receives $6.8M grant to study how environmental chemicals increase CVD risk

Exposure to environmental chemicals, including those in common plastic products, has been linked with an increased risk of cardiovascular disease, or CVD, the leading cause of death worldwide. According to the World Health Organization, 17.9 million people died from CVDs in 2019.

16 Aug 2023

Next-generation sequencing provides novel insights into the mechanisms underlying autism and myotonic muscular dystrophy

The pathomechanistic connection between autism and myotonic muscular dystrophy type 1.

16 Aug 2023

Study shows how brain rhythms can affect brain function by altering microglia and cytokines

Researchers used visual flickering sensory stimulation to reveal the underlying mechanisms governing microglial morphology and cytokine expression in mice.

16 Aug 2023

Scientists discover potential biomarkers linked to metastatic prostate cancer in Black men

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, have identified a cell metabolism process found in men with diabetes and metastatic prostate cancer that could one day lead to improved testing and treatments for Black men with these diseases.

15 Aug 2023

Epigenetic manipulation may improve breast cancer treatment responses

Researchers explore the possibility of increasing TROP2 ADC activity by enhancing the expression of TROP2 on cancer cells.

15 Aug 2023

Deep learning framework DeepAIR could improve understanding of adaptive immunity

Researchers presented a deep learning framework, DeepAIR, to accurately predict adaptive immune receptor (AIR)-antigen binding.

15 Aug 2023

Genetic determinants of retinol circulation and their impact on health

The genetic architecture of circulating retinol.

15 Aug 2023

A computational model identifies metabolites associated with Parkinson's disease

Researchers identify significant metabolites involved in the development and progression of Parkinson’s disease.

15 Aug 2023

Epigenetic drug-sensitive biomarkers for cancer

Researchers perform an epigenome-wide multi-omic high-throughput screen to identify actionable epigenetic drug-sensitive biomarkers.

15 Aug 2023

Oncolytic viruses could be used to 'warm up' cold tumors and improve immunotherapy

Equipping cancer-infecting, or oncolytic, viruses with tumor-inhibiting genetic cargo stimulates the immune system and helps immunotherapy to shrink or completely clear aggressive tumors in mice, according to a new study in the Journal of Experimental Medicine led by University of Pittsburgh and UPMC researchers.

14 Aug 2023

Study finds way to reverse gene silencing in inner ear cells

A deafened adult cannot recover the ability to hear, because the sensory hearing cells of the inner ear don't regenerate after damage.

14 Aug 2023

Stem cells used to create organoids that secrete dental enamel proteins

Organoids have now been created from stem cells to secrete the proteins that form dental enamel, the substance that protects teeth from damage and decay.

14 Aug 2023

Study discovers new mechanism for deadly tumor switch in prostate cancer

A study from the University of Michigan Rogel Cancer Center uncovers a new mechanism to explain why some prostate tumors switch from a common, treatable form to a more rare and aggressive form of prostate cancer.

14 Aug 2023

Study yields new knowledge about genes responsible for IgG production and release

A collaboration led by UCLA and the Seattle Children's Research Institute has yielded new knowledge about the genes responsible for the production and release of immunoglobulin G, the most common type of antibody in the human body.

14 Aug 2023

UAB researchers identify cell-surface marker that indicates fate of T cells

Follicular helper T cells, or Tfh cells, have a crucial role in immune defense. Without Tfh cells, B cells cannot form germinal center, or GC, responses during which high-affinity antibodies are generated.

14 Aug 2023

Kidney cancer study reveals new findings about MiTF family gene mutations

A new study from clinicians and researchers at the University of Michigan Rogel Cancer Center, U-M Department of Pathology and the Michigan Center for Translational Pathology reveals findings from over 800 clinical assays performed for kidney patients with MiTF family gene mutations.

14 Aug 2023

Gene News and Research

Latest Gene News and Research

Study sheds light on how cold temperatures affect appetite

Pig kidney xenotransplantation continues to function well after 32 days

Long DNA molecules reveal new scar types in HR-deficient cancers

Sulfate groups on complex sugar molecules affect brain plasticity

Scientist receives $6.8M grant to study how environmental chemicals increase CVD risk

Next-generation sequencing provides novel insights into the mechanisms underlying autism and myotonic muscular dystrophy

Study shows how brain rhythms can affect brain function by altering microglia and cytokines

Scientists discover potential biomarkers linked to metastatic prostate cancer in Black men

Epigenetic manipulation may improve breast cancer treatment responses

Deep learning framework DeepAIR could improve understanding of adaptive immunity

Genetic determinants of retinol circulation and their impact on health

A computational model identifies metabolites associated with Parkinson's disease

Epigenetic drug-sensitive biomarkers for cancer

Oncolytic viruses could be used to 'warm up' cold tumors and improve immunotherapy

Study finds way to reverse gene silencing in inner ear cells

Stem cells used to create organoids that secrete dental enamel proteins

Study discovers new mechanism for deadly tumor switch in prostate cancer

Study yields new knowledge about genes responsible for IgG production and release

UAB researchers identify cell-surface marker that indicates fate of T cells

Kidney cancer study reveals new findings about MiTF family gene mutations

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research