Gene News and Research

Latest Gene News and Research

Mitophagy helps blood cancer cells to evade the killing effects of BH3 mimetic drug

Despite the promise of new medications that promote cancer cell death in people with acute myeloid leukemia, leukemic cells often adopt features that let them evade the drugs' effects within a year.

24 Apr 2023

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Researchers at the Johns Hopkins Kimmel Cancer Center identified a novel cell signaling pathway that potentially could be targeted in therapy for patients with aggressive pancreatic cancers.

24 Apr 2023

Discovery about inflammation ‘brake’ gene paves way to personalized treatments for kidney disease

A discovery about gene variants of an inflammation 'brake' brings scientists a step closer to personalised treatment for patients at risk of kidney disease and kidney failure.

24 Apr 2023

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

CMPK2 identified as a potential pan-flavivirus inhibitor, restricting virus replication and providing a basis for developing new antiviral treatments.

23 Apr 2023

New tool offers high accuracy in the interpretation of genetic mutations in disease genes

Despite the increasing use of genomic sequencing in clinical practice, interpreting rare genetic mutations, even among well-studied disease genes, remains difficult.

21 Apr 2023

New injectable cell therapy shows promise for treating osteoarthritis

Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have created a promising injectable cell therapy to treat osteoarthritis that both reduces inflammation and also regenerates articular cartilage.

21 Apr 2023

Super-polymers are used by gut bacteria to fend off antibiotics

The discovery shows why it can be so difficult to tackle drug-resistant bacteria, but does provide a possible avenue for tackling the problem.

21 Apr 2023

Research reveals a more effective treatment for multiple sclerosis patients

Degeneration of myelin, an insulating sheath required for rapid communication between nerve cells, and neuroinflammation are notable hallmarks of Multiple Sclerosis (MS) and related neurodegenerative disorders such as Alzheimer's disease or Huntington's disease that affect roughly 2.8 million people in the world.

21 Apr 2023

Using a gene signature to predict cancer patient's response to chemotherapy agent cisplatin

Researchers at Cleveland Clinic have taken an important step in predicting which treatment will work for individual cancer patients.

21 Apr 2023

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20th in the open access journal PLOS Biology by Bing Ye of the University of Michigan, US, and colleagues.

21 Apr 2023

RExMap unlocks gut microbiome secrets: Revealing their global influence on health

Groundbreaking RExMap database enables species-level mapping of gut microbes, revealing a core set of fifteen microbes shared by humans across the globe.

21 Apr 2023

Brain's glucose metabolism: Key to unlocking new therapies for Alzheimer's and Parkinson's

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20 Apr 2023

TONSL gene could be a new target for breast cancer treatment

While trying to understand what initiates breast cells to become cancerous, researchers at the Vera Bradley Foundation Center for Breast Cancer Research at Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified a new target for breast cancer treatment.

20 Apr 2023

Study links astrocytic TDP-43 dysfunction to cognitive decline in dementia: Unlocking potential therapeutic strategies

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20 Apr 2023

Newly discovered genetic variant increases risk of developing perianal Crohn's disease

Cedars-Sinai investigators have identified a genetic variant that increases people's risk of developing perianal Crohn's disease, the most debilitating manifestation of Crohn's disease.

20 Apr 2023

Gestational obesity plus zika virus infection can compromise placenta’s immune response

Researchers at the University of São Paulo (USP) in Brazil have shown for the first time that gestational obesity associated with infection by zika virus influences the placenta's antiviral response, weakening the organ's capacity to attack the pathogen and protect the fetus.

20 Apr 2023

New drug may offer relief for people with difficult-to-treat migraine

The drug atogepant may help prevent migraines for people who have had no success with other preventive drugs, according to a preliminary study released April 20, 2023, which will be presented at the American Academy of Neurology's 75th Annual Meeting being held in person in Boston and live online from April 22-27, 2023.

20 Apr 2023

Common infections in mid- and late-life can worsen cognitive performance

A new study from a team led by researchers at the Johns Hopkins Bloomberg School of Public Health found that signs of common infections in a sample of middle-aged and older adults were associated with poorer performance on a test of global cognitive function.

20 Apr 2023

Using engineered stem cells to treat ALS and retinitis pigmentosa

Cedars-Sinai investigators are developing a novel way to treat amyotrophic lateral sclerosis (ALS) and retinitis pigmentosa using engineered stem cells that may eventually lead to personalized treatments.

20 Apr 2023

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

Researchers explored increasing replicative fitness of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants

20 Apr 2023

Gene News and Research

Latest Gene News and Research

Mitophagy helps blood cancer cells to evade the killing effects of BH3 mimetic drug

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Discovery about inflammation ‘brake’ gene paves way to personalized treatments for kidney disease

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

New tool offers high accuracy in the interpretation of genetic mutations in disease genes

New injectable cell therapy shows promise for treating osteoarthritis

Super-polymers are used by gut bacteria to fend off antibiotics

Research reveals a more effective treatment for multiple sclerosis patients

Using a gene signature to predict cancer patient's response to chemotherapy agent cisplatin

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

RExMap unlocks gut microbiome secrets: Revealing their global influence on health

Brain's glucose metabolism: Key to unlocking new therapies for Alzheimer's and Parkinson's

TONSL gene could be a new target for breast cancer treatment

Study links astrocytic TDP-43 dysfunction to cognitive decline in dementia: Unlocking potential therapeutic strategies

Newly discovered genetic variant increases risk of developing perianal Crohn's disease

Gestational obesity plus zika virus infection can compromise placenta’s immune response

New drug may offer relief for people with difficult-to-treat migraine

Common infections in mid- and late-life can worsen cognitive performance

Using engineered stem cells to treat ALS and retinitis pigmentosa

Study indicates that SARS-CoV-2 has evolved to gain increased replicative fitness and become well-adapted in epithelial cells of human airways

eBook: Using iPSCs models for human disease research and drug discovery eBook

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

How cohesin mechanics and nanotracker tech are redefining DNA research