Gene News and Research

Latest Gene News and Research

Two waves of Pitx2 expression orchestrate gut rotation during development, study finds

Our guts, and all our organs, are arranged in left-right asymmetric patterns inside our bodies, so that everything may fit.

23 Sep 2022

Research reveals how carp virus uses a protein domain to inhibit host cell’s defense mechanisms

The team of Prof. Alain Vanderplasschen, virologist and immunologist at the University of Liège, has published an article in the journal Nucleic Acids Research, reporting ten years of research on how a carp virus has been using a protein domain called Zalpha (Zα) to inhibit the defense mechanisms of the host cell.

23 Sep 2022

Genome editing approaches enable precise gene correction and disease rescue in inherited retinal diseases

In a new paper, University of California, Irvine researchers explain how precision genome editing agents have enabled precise gene correction and disease rescue in inherited retinal diseases (IRDs).

23 Sep 2022

Scientists create new tool to identify genomic safe harbor sites in specific tissues

Scientists at St. Jude Children's Research Hospital have created a tool that can find safe places to introduce genes into human DNA.

22 Sep 2022

Newly discovered gene marker may lead to a precision treatment for pancreatic cancer

Researchers at Mayo Clinic Comprehensive Cancer Center have identified a gene marker that may lead to a more effective, precision treatment for pancreatic ductal adenocarcinoma (PDAC).

22 Sep 2022

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

Monon Bioventures LLC has received a one-year, $398,314 Phase I Small Business Innovation Research, or SBIR grant from the National Cancer Institute to demonstrate the feasibility of manufacturing a glioblastoma therapeutic created at the Purdue University College of Pharmacy.

22 Sep 2022

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

Two scientists at the David Geffen School of Medicine at UCLA have been awarded nearly $10 million from the National Institutes of Health's Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative for research projects that aim to shed light on the developing brain's cellular infrastructure to better understand brain disorders.

22 Sep 2022

New imaging approach could help accelerate the development of new treatments for eye diseases

Researchers have developed a simple and fast way to perform optoretinography, an imaging technique that measures light-induced functional activity in the eye's retina, the network of neurons in the back of our eyes responsible for detecting light and initiating vision.

22 Sep 2022

Salk scientists launch a new Center for Multiomic Human Brain Cell Atlas with $126 million NIH grant

With a five-year, $126 million grant from the National Institutes of Health, a team led by Salk Institute scientists has launched a new Center for Multiomic Human Brain Cell Atlas.

22 Sep 2022

New board members bring significant leadership experience in the biotech sector

Aspect Biosystems, a biotechnology company pioneering the development of bioprinted tissue therapeutics to transform how we treat disease, is pleased to announce the appointment of three new members to its Board of Directors: Dr. Nancy Krieger, Dr. Don Haut, and Dr. Devyn Smith.

From Aspect Biosystems 22 Sep 2022

New modeling system identifies potential therapeutics for autosomal recessive polycystic kidney disease

Organoids - lab grown cells or tissues that resemble organs - serve as a new tool for disease modeling, but researchers often have difficulty replicating the biophysical conditions in which the organs operate within the body.

22 Sep 2022

Human gene variant in ADHD, autism exposes sex-dependence of neuronal signaling mechanisms

The prevalence, age of onset, and clinical symptoms for virtually all neuropsychiatric disorders differ between men and women. Among the disorders with pronounced sex bias are Attention-Deficit/Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD), where the ratio of males/females diagnosed is approximately 4 to 1.

21 Sep 2022

Virology of the human monkeypox virus

A new review to be posted in the Virus Research journal aims to provide an overview of the recent advances reported concerning hMPXV virology.

21 Sep 2022

New genetically-targeted MND therapy could be a turning point for patient care

Scientists believe a new genetically-targeted therapy to treat motor neurone disease (MND) could be a turning point for patient care, after the results of a Phase 3 clinical trial showed significant physical benefits for patients after 12 months.

21 Sep 2022

New genetic discovery improves understanding of congenital heart disease

A new study led by the Masonic Medical Research Institute published in the journal Cells shows for the first time that a particular gene, called VGLL4, is required for embryo development but is dispensable for myocardial growth.

21 Sep 2022

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer's disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, according to a new USC study.

21 Sep 2022

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Researchers described a novel antiviral mechanism of action for an FDA (food and drug administration)-approved thiopurine known as 6-thioguanine (6-TG).

21 Sep 2022

Common genetic variants of APOE associated with COVID mortality

It may be the most baffling quirk of COVID: What manifests as minor, flu-like symptoms in some individuals spirals into severe disease, disability, and even death in others.

21 Sep 2022

Why fatigue from long COVID goes beyond simply feeling tired

In a recent study posted to the medRxiv* preprint server, researchers in the Netherlands examined the role of inflammatory genes, cytotoxic T-lymphocytes (CD8+ T cells), and pro-inflammatory cytokines in long-lasting severe fatigue experienced by a large number of coronavirus disease 2019 (COVID-19) patients.

21 Sep 2022

Evidence A.2 lineage of monkeypox is mutating

In a recent study posted to the bioRxiv* preprint server, a team of researchers from India analyzed the whole genome sequences of the monkeypox virus isolated from monkeypox patients with and without international travel histories to understand the phylogenetic relations and genomic evolution of the virus that could contribute to higher transmission rates.

21 Sep 2022

Gene News and Research

Latest Gene News and Research

Two waves of Pitx2 expression orchestrate gut rotation during development, study finds

Research reveals how carp virus uses a protein domain to inhibit host cell’s defense mechanisms

Genome editing approaches enable precise gene correction and disease rescue in inherited retinal diseases

Scientists create new tool to identify genomic safe harbor sites in specific tissues

Newly discovered gene marker may lead to a precision treatment for pancreatic cancer

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

New imaging approach could help accelerate the development of new treatments for eye diseases

Salk scientists launch a new Center for Multiomic Human Brain Cell Atlas with $126 million NIH grant

New board members bring significant leadership experience in the biotech sector

New modeling system identifies potential therapeutics for autosomal recessive polycystic kidney disease

Human gene variant in ADHD, autism exposes sex-dependence of neuronal signaling mechanisms

Virology of the human monkeypox virus

New genetically-targeted MND therapy could be a turning point for patient care

New genetic discovery improves understanding of congenital heart disease

Mutation in newly discovered small protein linked to increase in Alzheimer's disease risk

New antiviral mechanism of action for an FDA-approved thiopurine known as 6-thioguanine

Common genetic variants of APOE associated with COVID mortality

Why fatigue from long COVID goes beyond simply feeling tired

Evidence A.2 lineage of monkeypox is mutating

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