Gene News and Research

Latest Gene News and Research

Spatial aging clocks reveal how T cells and neural stem cells shape brain aging

Researchers developed spatial aging clocks to map brain cell aging, revealing how T cells accelerate aging and NSCs rejuvenate neighboring cells, offering new insights into brain health and interventions.

22 Dec 2024

New research project aims to uncover molecular factors behind malaria’s deadliest strain

Nearly half the world's population lives in regions where malaria is endemic, with the parasite Plasmodium falciparum accounting for approximately 95% of malaria-related deaths globally.

20 Dec 2024

Solving a decades-long puzzle in leishmaniasis drug development

A breakthrough in understanding how a single-cell parasite makes ergosterol (its version of cholesterol) could lead to more effective drugs for human leishmaniasis, a parasitic disease that afflicts about 1 million people and kills about 30,000 people around the world every year.

20 Dec 2024

Unexpected discovery opens doors for improved siRNA therapies

In everyday life, when things turn out the opposite of what you expect, it's usually cause for frustration. In science, it's often the starting point for discovery.

20 Dec 2024

New synthetic biology breakthrough improves genetic circuit integration

The research team led by Professor Jongmin Kim from the Department of Life Sciences at POSTECH, along with graduate students Hyunseop Goh and Seungdo Choi, has successfully developed the 'Synthetic Translational Coupling Element (SynTCE),' significantly enhancing the precision and integration density of genetic circuits in synthetic biology.

20 Dec 2024

Host heterogeneity increases pathogen virulence in metapopulations

Heterogeneity is ubiquitous in real-world host populations, yet most theories assume homogeneity. Using a metapopulation model, we examine how host heterogeneities, such as uneven movement patterns and local productivities, affect the evolution of pathogen virulence.

20 Dec 2024

Pioneering research identifies three subtypes of osteosarcoma for better treatment

Researchers have been able to identify at least three distinct subtypes of a rare type of bone cancer for the first time, which could transform clinical trials and patient care.

20 Dec 2024

Shiitake-based supplement may help prevent liver damage progression

AHCC demonstrates potential in preventing liver fibrosis progression by inhibiting HSC activation and regulating key pathways involved in liver injury.

20 Dec 2024

Long-term green tea catechins prevent aging-related cardiac dysfunction

A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101284, discusses the effect of long-term administration of green tea catechins on aging-related cardiac diastolic dysfunction and decline of troponin I.

20 Dec 2024

Insights into LKB1's role in tumorigenesis

A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101402, discusses insights into targeting LKB1 in tumorigenesis.

20 Dec 2024

Novel photosensitizer Ce6-GFFY shows promise for colorectal cancer therapy

A new publication from Genes & Diseases; DOI 10.1016/j.gendis.2024.101441, discusses how Ce6-GFFY is a novel photosensitizer for colorectal cancer therapy.

20 Dec 2024

New insights into glioblastoma resistance to temozolomide

In spite of intensive research, glioblastoma remains one of the most lethal types of brain cancer. Temozolomide (TMZ) is used as the front-line medicine in its treatment.

19 Dec 2024

Study uncovers a previously unknown genetic link to autism spectrum disorder

New research published in The American Journal of Human Genetics has identified a previously unknown genetic link to autism spectrum disorder (ASD). The study found that variants in the DDX53 gene contribute to ASD, providing new insights into the genetic underpinnings of the condition.

19 Dec 2024

New molecular insights into the early stages of Rett syndrome

Scientists investigating the severe developmental disorder known as Rett syndrome have discovered a series of crucial molecular changes that occur long before symptoms appear.

19 Dec 2024

Chronic gut infection may play role in Alzheimer’s disease progression

Arizona State University and Banner Alzheimer's Institute researchers, along with their collaborators, have discovered a surprising link between a chronic gut infection caused by a common virus and the development of Alzheimer's disease in a subset of people.

19 Dec 2024