Gene News and Research

Latest Gene News and Research

SARS-CoV-2 protein NSP2 found to impair microRNA-induced gene silencing in human cells

In a new study, a team of researchers used co-immunoprecipitation and in vitro interaction assays to identify the molecular basis of interaction of SARS-CoV-2 non-structural protein 2 with eIF4E-homologous protein (4EHP)-GRB10-interacting glycine-tyrosine-phenylalanine domain protein 2 complex, involved in microRNA-mediated gene silencing in human cells.

1 Feb 2022

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

In a new study, researchers evaluated the neutralizing antibody titers in mice vaccinated with messenger ribonucleic acid (mRNA) encoding SARS-CoV-2 spike (S) protein.

1 Feb 2022

Researchers develop new technique to open the blood-brain barrier in lab animals

University of Maryland School of Medicine researchers developed a technique in laboratory animals to consistently and reproducibly open the blood-brain barrier.

31 Jan 2022

Fusion oncogenes associated with more invasive pediatric thyroid cancers, study says

Fusion oncogenes, such as RET- and NTRK-gene fusions, are associated with more invasive pediatric thyroid cancers, correlating with the highest risk of metastases and a lower likelihood of achieving remission one year after initial therapy, according to a new study by researchers at Children's Hospital of Philadelphia (CHOP).

31 Jan 2022

Dexamethasone administration at a late time point could enhance transgene expression

Dexamethasone, a glucocorticoid with anti-inflammatory and immunosuppressive effects, can transiently increase the expression of therapeutic genes delivered using adeno-associated virus (AAV) vectors.

31 Jan 2022

New study on mutation origination fundamentally challenges neo-Darwinism

A new study by a team of researchers from Israel and Ghana has brought the first evidence of nonrandom mutation in human genes, challenging a core assumption at the heart of evolutionary theory by showing a long-term directional mutational response to environmental pressure.

31 Jan 2022

Researchers identify genetic cause of rare interstitial lung disease in a young child

New research from Washington University School of Medicine in St. Louis has solved the medical mystery of why a 2-year-old child — seemingly healthy at birth — succumbed to an undiagnosed, rare illness.

31 Jan 2022

Study identifies drugs that could help combat mortality in patients with COVID-19

Inflammation is a defense mechanism of the body to fight pathogens. However, when it is widespread and excessive, it can aggravate the pathology and even cause death.

31 Jan 2022

Study reveals potential mechanism for iron accumulation in the aging brain

Breakdowns in regulatory mechanisms cause iron to build up in the brain as organisms grow older, increasing oxidative stress and causing cellular damage, according to a Northwestern Medicine study published in the journal eLife.

31 Jan 2022

Study finds how a change in cell environment triggers autism with genetic vulnerability

People with autism spectrum disorders all have characteristic behavioral difficulties. Nevertheless, the important heterogeneity of their symptoms remains one of the major questions for scientists and physicians.

31 Jan 2022

Escape from vaccine-induced immunity likely contributed to rapid rise of SARS-CoV-2 Omicron

Researchers investigate whether the SARS-CoV-2 Omicron variant is more likely to infect vaccinated individuals than the SARS-CoV-2 Delta variant.

30 Jan 2022

Study reveals link between muscular dystrophy and sphingolipids

In a new study, the group of Johan Auwerx at EPFL's School of Life Sciences has made the first connection between muscular dystrophy and sphingolipids, a group of bioactive lipids. The study is published in Science Advances.

29 Jan 2022

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

The Damon Runyon Cancer Research Foundation has announced its newest cohort of Damon Runyon Fellows, 13 outstanding postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

29 Jan 2022

New approach accelerates the detection of cancer biomarkers for point-of-care diagnostics

The detection and quantification of cancer-associated molecular biomarkers in body fluids, or liquid biopsies, prove minimally invasive in early cancer diagnostics.

29 Jan 2022

Study identifies high-priority genes associated with uterine cancer that could be potential drug targets

No single gene causes uterine cancer, the fourth most common cancer among women, which is on the rise in the U.S.

28 Jan 2022

Study reveals role of a protein in healthy functioning of blood stem cells

A protein that masterminds the way DNA is wrapped within chromosomes has a major role in the healthy functioning of blood stem cells, which produce all blood cells in the body, according to a new study from researchers at Weill Cornell Medicine.

28 Jan 2022

Study identifies genetic link between early maturation and high aerobic performance in juvenile salmon

A study conducted at the University of Helsinki indicates that early sexual maturation and high aerobic performance in salmon have a genetic link that is already evident in juvenile salmon.

28 Jan 2022

Evidence on intra-host recombination of SARS-CoV-2 during superinfection by Alpha and Epsilon variants in USA

A new study captured an instance of SARS-CoV-2 superinfection in an individual, simultaneously infected by two SARS-CoV-2 variants, Alpha and Epsilon during the second COVID-19 wave in New York City in early 2021.

28 Jan 2022

γ’ fibrinogen as a disease progression marker for COVID-19

Levels of the inflammatory biomarker gamma prime fibrinogen (γ' Fbg) varies according to severity in COVID-19 patients.

28 Jan 2022

Potential therapy candidates for patients infected with the SARS-CoV-2 Omicron variant

Researcher discusses several promising therapeutic candidates that have been proposed for the treatment of patients infected with the Omicron variant.

28 Jan 2022

Gene News and Research

Latest Gene News and Research

SARS-CoV-2 protein NSP2 found to impair microRNA-induced gene silencing in human cells

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

Researchers develop new technique to open the blood-brain barrier in lab animals

Fusion oncogenes associated with more invasive pediatric thyroid cancers, study says

Dexamethasone administration at a late time point could enhance transgene expression

New study on mutation origination fundamentally challenges neo-Darwinism

Researchers identify genetic cause of rare interstitial lung disease in a young child

Study identifies drugs that could help combat mortality in patients with COVID-19

Study reveals potential mechanism for iron accumulation in the aging brain

Study finds how a change in cell environment triggers autism with genetic vulnerability

Escape from vaccine-induced immunity likely contributed to rapid rise of SARS-CoV-2 Omicron

Study reveals link between muscular dystrophy and sphingolipids

Damon Runyon Cancer Research Foundation announces newest cohort of Fellows and Breakthrough Scientists

New approach accelerates the detection of cancer biomarkers for point-of-care diagnostics

Study identifies high-priority genes associated with uterine cancer that could be potential drug targets

Study reveals role of a protein in healthy functioning of blood stem cells

Study identifies genetic link between early maturation and high aerobic performance in juvenile salmon

Evidence on intra-host recombination of SARS-CoV-2 during superinfection by Alpha and Epsilon variants in USA

γ’ fibrinogen as a disease progression marker for COVID-19

Potential therapy candidates for patients infected with the SARS-CoV-2 Omicron variant

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging