Gene News and Research

Latest Gene News and Research

Gene replacement therapy could help mend a broken heart, study suggests

How can you mend a broken heart? According to researchers from Japan, in some cases gene replacement therapy just might do the trick.

24 Jan 2022

Researchers find ELF5 gene a leading candidate behind severe COVID-19

Are there any risk factors that predispose patients to severe COVID-19 outcomes? A recent study published in the medRxiv* preprint server sheds light on this popular question. Using a combination of population genetics to single-cell RNA sequencing, European researchers identified the respiratory epithelial cell-specific ELF5 gene as a potential mediator for severe COVID-19 cases.

24 Jan 2022

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

In a recent study posted to the bioRxiv* preprint server, researchers developed a novel bioinformatic algorithm to predict host cleavage targets of the SARS-CoV-2 3C-like protease (3CLPro).

23 Jan 2022

Genetic marker linked to higher risk of death in COVID-19 patients

A new study discusses the importance of single nucleotide polymorphisms in the Rab46 gene as a marker of adverse outcomes in high-risk COVID-19 patients.

23 Jan 2022

Novel SARS-CoV-2 mutations reported in chronic HIV patients

A new study describes the emergence of new SARS-CoV-2 variants in three immunocompromised patients.

23 Jan 2022

SARS-CoV-2 Omicron associated with fewer lower and more upper respiratory tract symptoms

Researchers assess the impact of the SARS-CoV-2 Omicron variant of concern on symptoms of SARS-CoV-2 infection.

23 Jan 2022

Study finds more than 1,000 gene-activation differences between female and male mouse brains

Male and female mouse brains differ in important ways, according to a new study led by Stanford Medicine investigators.

22 Jan 2022

Scientists develop new drug delivery system for treating genetic diseases

A team of researchers led by Harvard and Broad Institute scientists has developed a new drug delivery system using engineered DNA-free virus-like particles (eVLPs) to package and deliver therapeutic levels of gene-editing proteins to animal models of disease.

22 Jan 2022

Alphacoronaviruses found to be common in bats in the upper Midwestern United States

In a new study, researchers used a pan-coronavirus PCR to screen bats submitted for rabies testing owing to human exposure in order to find potentially novel bat CoVs that may represent a concern to people.

21 Jan 2022

SARS-CoV-2 prevalence in bivalve mollusks from harvesting areas in Southern Italy

The goal of the current study was to collect data on the prevalence of SARS-CoV-2 in bivalve mollusks harvested in the Campania region using dd RT-PCR for the detection of low levels of virus in mollusk tissues.

21 Jan 2022

Cannabidiol found to inhibit SARS-CoV-2 infection in human cells and mice

An interdisciplinary team of researchers from the University of Chicago has found evidence that cannabidiol (CBD), a product of the cannabis plant, can inhibit infection by SARS-CoV-2 in human cells and in mice.

21 Jan 2022

High-speed cell sorter uses fluorescence imaging to enable genome-scale studies of complex phenotypes

Isolating individual cells with complex phenotypes – which is key to understanding how these cells function, including to inform disease – is a technological challenge. Now, overcoming this hurdle, researchers present a high-speed cell sorter that uses fluorescence imaging to enable genome-scale studies of complex phenotypes.

21 Jan 2022

Tau mapping offers potential treatment targets and biomarkers for dementia and Alzheimer disease

By mapping all the protein interactions of a dementia-linked protein in the brain called Tau, a team of Weill Cornell Medicine investigators has created a road map for identifying potential new treatment targets for Alzheimer's disease and related dementia.

21 Jan 2022

PAXLOVID shown to be highly effective against all SARS-CoV-2 variants

A recent study, currently available on bioRxiv* preprint server, shows that a novel protease inhibitor known as nirmatrelvir has potent activity against Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also other variants evaluated in this paper – which supports its potential role in reducing the disease burden from coronavirus disease 2019 (COVID-19).

21 Jan 2022

Fully dynamic kinetic model of a living 'minimal cell' offers insight into basic principles of life

Scientists report that they have built a living "minimal cell" with a genome stripped down to its barest essentials – and a computer model of the cell that mirrors its behavior.

20 Jan 2022

Researchers identify first known patients with BUB1 biallelic mutations

A new study published in Science Advances described the first two patients known to have mutations in both copies of BUB1, a critical gene for cell division.

20 Jan 2022

UAB research outlines successful xenotransplantation of genetically modified kidneys

The University of Alabama at Birmingham Marnix E. Heersink School of Medicine announces today the first peer-reviewed research outlining the successful transplant of genetically modified, clinical-grade pig kidneys into a brain-dead human individual, replacing the recipient's native kidneys.

20 Jan 2022

Study finds Omicron infection effectively induces immunity against itself and enhances protection against other variants in vaccinated individuals

Researchers investigated the effectiveness of the SARS-CoV-2 Omicron-variant induced immunity, whether it is cross-protective against other variants, and if earlier infection with the SARS-CoV-2 Delta variant offers protection against Omicron.

20 Jan 2022

Recombinant bat coronavirus reported in wide-ranging Cambodian bat

A new study reports on the detection of recombinant coronaviruses in several bat species in Cambodia and of a related species in China.

20 Jan 2022

Exploring the potential utility of calcium channel inhibitors in SARS-CoV-2 infection

In a new study, researchers discuss the role of calcium signaling pathways as targets of inhibition in potential new antiviral therapeutic pathways for SARS-CoV-2.

20 Jan 2022

Gene News and Research

Latest Gene News and Research

Gene replacement therapy could help mend a broken heart, study suggests

Researchers find ELF5 gene a leading candidate behind severe COVID-19

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

Genetic marker linked to higher risk of death in COVID-19 patients

Novel SARS-CoV-2 mutations reported in chronic HIV patients

SARS-CoV-2 Omicron associated with fewer lower and more upper respiratory tract symptoms

Study finds more than 1,000 gene-activation differences between female and male mouse brains

Scientists develop new drug delivery system for treating genetic diseases

Alphacoronaviruses found to be common in bats in the upper Midwestern United States

SARS-CoV-2 prevalence in bivalve mollusks from harvesting areas in Southern Italy

Cannabidiol found to inhibit SARS-CoV-2 infection in human cells and mice

High-speed cell sorter uses fluorescence imaging to enable genome-scale studies of complex phenotypes

Tau mapping offers potential treatment targets and biomarkers for dementia and Alzheimer disease

PAXLOVID shown to be highly effective against all SARS-CoV-2 variants

Fully dynamic kinetic model of a living 'minimal cell' offers insight into basic principles of life

Researchers identify first known patients with BUB1 biallelic mutations

UAB research outlines successful xenotransplantation of genetically modified kidneys

Study finds Omicron infection effectively induces immunity against itself and enhances protection against other variants in vaccinated individuals

Recombinant bat coronavirus reported in wide-ranging Cambodian bat

Exploring the potential utility of calcium channel inhibitors in SARS-CoV-2 infection

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging