Gene News and Research

Latest Gene News and Research

Direct effect of SARS-CoV-2 on the kidney

Researchers infected human-induced pluripotent-stem-cell (iPSC)-derived kidney organoids with SARS-CoV-2 to study the virus's direct effect on the kidney.

18 Jan 2022

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

A Parkinson’s disease gene turns out to provide the key to modify diseases related to immunoaging.

18 Jan 2022

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

A Parkinson’s disease gene turns out to provide the key to modify diseases related to immunoaging.

18 Jan 2022

UniSA scientists make a surprising discovery in the origins of antibiotic-resistant gene

University of South Australia scientists have made a surprising discovery in the origins of an antibiotic-resistant gene previously thought to have been confined to Adelaide.

18 Jan 2022

An alternative mouse model of SARS-CoV-2 infection

Recently, a study has shown the possibility of repurposing hACE2 transgenic mice, primarily raised to study SARS-CoV, to support SARS-CoV-2 infection and pathogenesis.

17 Jan 2022

DPP4 protein: The connection between severe COVID-19 and diabetes

Researchers explore the relationship between DPP4 and diabetes targets in the management of COVID-19.

17 Jan 2022

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

A new study focused on the pathomorphological and virological characterization of SARS-CoV-2 in naturally infected, wild Indian Leopard.

17 Jan 2022

Researchers investigate the role of a key component of the circadian clock in heart disease

Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart disease, but it is unclear how it leads to the condition.

17 Jan 2022

Study finds evidence to strongly implicate OAS1 as an effector gene influencing COVID-19 severity

Researchers demonstrated that this splice variant is likely to be the single nucleotide polymorphism responsible for the association at this locus.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

A new paper discusses the appearance of quasi-species in a single host with prolonged infection, with different rates of infectivity and sensitivity to neutralization by antibodies elicited by the Pfizer vaccine or those present in convalescent plasma.

17 Jan 2022

Study identifies cellular receptors for alphaviruses shared across mosquitoes, humans, and animals

A new study led by researchers at Harvard Medical School has identified a set of cellular receptors for at least three related alphaviruses shared across mosquitoes, humans, and animals that host the virus.

17 Jan 2022

Researchers engineer enucleated cells to deliver therapeutics precisely to diseased tissues

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health report successfully removing the nucleus out of a type of ubiquitous cell, known as enucleation, then using the genetically engineered cell as a unique cargo-carrier to deliver therapeutics precisely to diseased tissues.

17 Jan 2022

Discovery opens up the possibility of pursuing new therapies for FOP

Fibrodysplasia ossificans progressiva (FOP) is a rare disease characterized by extensive bone growth outside of the normal skeleton that pre-empts the body's normal responses to even minor injuries. It results in what some term a "second skeleton," which locks up joint movement and could make it hard to breathe.

16 Jan 2022

Genome editing in vascular endothelial cells made possible with a powerful new delivery system

Northwestern Medicine scientists developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which line blood vessel walls.

16 Jan 2022

Cannabidiol may improve innate immune response against SARS-CoV-2

A recent study shows evidence that cannabidiol, an important active ingredient in the Cannabis sativa plant, can augment the antiviral innate immune response and prophylactically prime the innate antiviral response of cells – enabling in turn improved response against viruses such as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Jan 2022

Study provides valuable insight into the developmental origins of schizophrenia

Scientists from Cardiff University have discovered new links between the breakdown in brain cell development and the risk of schizophrenia and other psychiatric disorders.

16 Jan 2022

UMass Amherst professor receives $2 million NIH MIRA grant for trailblazing research

Jianhan Chen, a University of Massachusetts Amherst chemistry and biochemistry and molecular biology professor, has received a five-year, $2 million National Institutes of Health (NIH) grant to support research in his computational biophysics lab aimed at better understanding the role of intrinsically disordered proteins (IDPs) in biology and human disease.

16 Jan 2022

Study shows Omicron less severe than Delta among COVID-19 hospitalized patients

New research posted to the medRxiv* preprint server suggests the Omicron variant produces less severe COVID-19 symptoms than earlier severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants.

16 Jan 2022

Asymptomatic COVID-19 patients less infectious than symptomatic patients

Researchers investigate the progression of infection in students and employees who tested positive for SARS-CoV-2 at Boston University.

16 Jan 2022

Gene News and Research

Latest Gene News and Research

Direct effect of SARS-CoV-2 on the kidney

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

Study reveals a causal link between deficiency in Parkinson’s disease gene and reduced immunoaging

UniSA scientists make a surprising discovery in the origins of antibiotic-resistant gene

An alternative mouse model of SARS-CoV-2 infection

DPP4 protein: The connection between severe COVID-19 and diabetes

Exploring the systemic infection of SARS-CoV-2 in a wild leopard in India

Researchers investigate the role of a key component of the circadian clock in heart disease

Study finds evidence to strongly implicate OAS1 as an effector gene influencing COVID-19 severity

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

Study demonstrates that intra-host SARS-CoV-2 variants with reduced infectivity are developed during infection

Study identifies cellular receptors for alphaviruses shared across mosquitoes, humans, and animals

Researchers engineer enucleated cells to deliver therapeutics precisely to diseased tissues

Discovery opens up the possibility of pursuing new therapies for FOP

Genome editing in vascular endothelial cells made possible with a powerful new delivery system

Cannabidiol may improve innate immune response against SARS-CoV-2

Study provides valuable insight into the developmental origins of schizophrenia

UMass Amherst professor receives $2 million NIH MIRA grant for trailblazing research

Study shows Omicron less severe than Delta among COVID-19 hospitalized patients

Asymptomatic COVID-19 patients less infectious than symptomatic patients

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging