Gene News and Research

Latest Gene News and Research

How do mosquito bites affect immunity?

A new study looks at the immunomodulatory effects of mosquito bites, using Aedes aegypti as the model species and humans as the host.

28 Apr 2022

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

A new review initially described the developments in cancer-based medicines that included vaccinations, vector-based techniques, and genome injection using DNA and RNA-based nucleic acid therapeutics.

28 Apr 2022

A cigarette smoke compound affects cartilage homeostasis

Cigarette smoke has been shown to deleteriously affect human health. For example, degenerative disc diseases are increasingly linked to cigarette smoking.

28 Apr 2022

MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

About one-fifth of often deadly head and neck cancers harbor genetic mutations in a pathway that is key to normal cell growth, and scientists report those mutations, which enable abnormal cancer cell growth, can also make the cancer vulnerable.

28 Apr 2022

Research reveals a therapeutic opportunity to prevent rhabdomyosarcoma recurrence

Rhabdomyosarcoma is a type of soft tissue cancer. Scientists at St. Jude Children's Research Hospital studied the population of cells that persists after therapy, causing rhabdomyosarcoma recurrence.

27 Apr 2022

Misexpression of non-cardiac genes may lead to congenital heart disease

Inside embryonic cells, specific proteins control the rate at which genetic information is transcribed from DNA to messenger RNA – a crucial regulatory step before proteins are created. Then, organs develop and hopefully function properly.

27 Apr 2022

Researchers use a systems biology approach to parse the genetic diversity of C. difficile

Researchers at University of California San Diego School of Medicine and Jacobs School of Engineering, with colleagues at Baylor College of Medicine, have used a systems biology approach to parse the genetic diversity of Clostridioides difficile, a particularly problematic pathogen in health care settings.

27 Apr 2022

“Keto” molecule could someday become a part of colorectal cancer care and prevention

A molecule produced in the liver in response to low-carb "ketogenic" diets has a powerful effect in suppressing colorectal tumor growth and may be useful as a preventive and treatment of such cancers, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

27 Apr 2022

Genetic cause of lupus identified

An international team of researchers has identified DNA mutations in a gene that senses viral RNA, as a cause of the autoimmune disease lupus, with the finding paving the way for the development of new treatments.

27 Apr 2022

Gene discovery could pave the way for new and more effective treatments for lupus

Researchers from The Australian National University have identified a gene called TLR7 that, when over-activated, is responsible for causing lupus, an autoimmune disease that can be life-threatening in severe cases.

27 Apr 2022

Comparative analysis of transcriptional responses across 13 different vaccines

A new study aimed to carry out a comparative analysis of transcriptional responses from 820 healthy young adults across 13 different vaccines.

27 Apr 2022

CRISPR/Cas9 deletions induce adverse on-target genomic effects

Researchers utilized a CRISPR/Cas9 system to evaluate the usage of tRNA by deleting two tRNA genes from the genomes of hyper hepatocellular carcinoma and human near-haploid chronic myeloid leukemia cells.

27 Apr 2022

Cellular reprogramming can lead to better liver tissue regeneration in mice

Mammals can't typically regenerate organs as efficiently as other vertebrates, such as fish and lizards. Now, Salk scientists have found a way to partially reset liver cells to more youthful states - allowing them to heal damaged tissue at a faster rate than previously observed.

27 Apr 2022

Researchers reveal how not-yet-malignant cells “turn on” and become metastatic breast cancer

Mount Sinai researchers have discovered a previously unknown mechanism in which not-yet-malignant cells from early breast cancer tumors travel to other organs and, eventually, "turn on" and become metastatic breast cancer.

26 Apr 2022

Johns Hopkins scientists receive $7.8 million funding from Break Through Cancer

The Johns Hopkins Kimmel Cancer Center and the Departments of Gynecology/Obstetrics, Neurosurgery and Pathology have been awarded more than $7.8 million for novel, multicenter projects designed to intercept and find cures for several deadly cancers, including pancreatic cancer, ovarian cancer, and the brain cancer known as glioblastoma.

26 Apr 2022

Study uncovers the regulator of cancer ‘stemness’

The protein FOXK2 promotes survival of cancer stem cells in ovarian cancer, according to a Northwestern Medicine study published in the Journal of Clinical Investigation.

26 Apr 2022

Genetic variations in critical mitochondrial enzyme play a role in age-related mobility changes

Age-related changes in strength and mobility may depend on genetic variations in a critical mitochondrial enzyme, suggests a study published today in eLife.

26 Apr 2022

Researchers use mouse model to explore correlation of impaired interferon-mediated immune response with severe COVID-19

Researchers developed a highly pathogenic mouse-adapted SARS-CoV-2 strain to model mild, moderate, or COVID-19.

26 Apr 2022

Evidence of increased intrinsic cleavability of SARS-CoV-2 Omicron spike protein by host cell furin

Researchers conducted an in vitro analysis to assess the host cell furin-mediated cleavability of the spike protein of the SARS-CoV-2 Omicron (B.1.529) variant.

26 Apr 2022

Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

My work is focused on looking at the dynamics of B/T cell populations within lymph nodes from patients that had recovered from COVID-19. My role in this research was developing and implementing microscopy image analysis techniques using methods and instrumentation in part supplied by TissueGnostics.

From TissueGnostics 26 Apr 2022

Gene News and Research

Latest Gene News and Research

How do mosquito bites affect immunity?

Exploring oncolytic viral therapeutics and immunotherapies derived from DNA and RNA

A cigarette smoke compound affects cartilage homeostasis

MAPK pathway mutations can provide “precision” treatment targets for head and neck cancer

Research reveals a therapeutic opportunity to prevent rhabdomyosarcoma recurrence

Misexpression of non-cardiac genes may lead to congenital heart disease

Researchers use a systems biology approach to parse the genetic diversity of C. difficile

“Keto” molecule could someday become a part of colorectal cancer care and prevention

Genetic cause of lupus identified

Gene discovery could pave the way for new and more effective treatments for lupus

Comparative analysis of transcriptional responses across 13 different vaccines

CRISPR/Cas9 deletions induce adverse on-target genomic effects

Cellular reprogramming can lead to better liver tissue regeneration in mice

Researchers reveal how not-yet-malignant cells “turn on” and become metastatic breast cancer

Johns Hopkins scientists receive $7.8 million funding from Break Through Cancer

Study uncovers the regulator of cancer ‘stemness’

Genetic variations in critical mitochondrial enzyme play a role in age-related mobility changes

Researchers use mouse model to explore correlation of impaired interferon-mediated immune response with severe COVID-19

Evidence of increased intrinsic cleavability of SARS-CoV-2 Omicron spike protein by host cell furin

Exploring Populations of B and T Cells in Lymph Nodes of Patients Diagnosed with COVID-19 via Microscopy and Image Analysis

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research