Gene News and Research

Latest Gene News and Research

Study suggests saliva swabs may be more suitable for omicron detection

New study findings reveal that saliva samples are more useful than mid-turbinate samples for the accurate detection of omicron infection.

29 Dec 2021

Human iPSC-derived fallopian tube organoids reveal the origins of common ovarian cancer

Stem cell scientists have revealed the origins of a common ovarian cancer by modeling fallopian tube tissues, allowing them to characterize how a genetic mutation puts women at high risk for this cancer.

29 Dec 2021

New study targets the methylation profile of microglia from human brain

In the central nervous system, microglial cells play critical roles in development, aging, brain homeostasis, and pathology. Recent studies have shown variation in the gene-expression profile and phenotype of microglia across brain regions and between different age and disease states.

29 Dec 2021

Structural blueprint of nanoparticles developed to target neutrophils responsible for acute lung inflammation

The COVID-19 pandemic highlighted the devastating impact of acute lung inflammation (ALI), which is part of the acute respiratory distress syndrome (ARDS) that is the dominant cause of death in COVID-19.

28 Dec 2021

Excessive intake of simple sugar in adolescents could be a risk factor of psychiatric disorders

There has been a remarkable increase in intake of simple sugar (sucrose, isomerized sugar (corn syrup)) from beverages and diets in modern society. The intake of simple sugars in adolescents in which mental disorders frequently occur is higher than any other generations.

28 Dec 2021

APOE4 allele gene linked to increased risk of severe COVID-19

A study conducted at the University of Helsinki and the Helsinki University Hospital suggests that the APOE4 allele may also increase cerebral microhemorrhages related to COVID-19 and associate with mental fatigue related to long COVID.

27 Dec 2021

LJI researchers discover how loss of TET enzymes can lead to B cell lymphoma

Scientists at the La Jolla Institute for Immunology have uncovered how loss of TET enzymes can lead to B cell lymphoma. Their research, published in Nature Immunology, could potentially open opportunities for designing drug treatment strategies to target malignant cells in many cancers.

24 Dec 2021

Single-patient pilot study shows the ability of antisense oligonucleotide to suppress mutant ALS gene

Using a short, synthetic chain of chemically modified nucleotides engineered in the RNA Therapeutics Institute at UMass Chan Medical School, Robert H. Brown Jr., DPhil, MD, Jonathan Watts, PhD, and colleagues have shown the ability to suppress mutant forms of an ALS gene known as C9ORF72 in a single-patient pilot study.

24 Dec 2021

Alpha variant of SARS-CoV-2 evolved mutations to evade the immune system

The Alpha variant of SARS-CoV-2 - the first "variant of concern" - evolved mutations that allowed it to more efficiently suppress the immune system's early response to infection, according to a new study led by scientists at the University of California, San Francisco's Quantitative Biosciences Institute and University College London.

24 Dec 2021

Are our bowel habits written in our DNA?

In this interview, News-Medical talks to Dr. Mauro D’Amato about how there could be clues about the regularity of bowel movements within our genes.

24 Dec 2021

Recently evolved region of the ‘dark genome’ provides clues to treatment of schizophrenia, bipolar disorder

Scientists investigating the DNA outside our genes - the 'dark genome' - have discovered recently evolved regions that code for proteins associated with schizophrenia and bipolar disorder.

23 Dec 2021

Omicron has enhanced infectivity that is only weakly neutralized by vaccination or prior infection

Scientists used virus-like particles and found that Omicron showed increased infectivity, relative to the B.1 and B.1.1 strains, which was similar to the Delta variant.

23 Dec 2021

Blocking function of a blood-clotting protein may help prevent or treat periodontal disease

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research, part of the National Institutes of Health.

23 Dec 2021

New insights into how red meat-rich diet increases cardiovascular disease risk

A Cleveland Clinic-led study has revealed new insights into how a diet rich in red meat increases risk for cardiovascular disease. The findings were published in Nature Microbiology and build on more than a decade of research by lead author Stanley Hazen, MD, PhD.

23 Dec 2021

Impact of the rapid spread of the SARS-CoV-2 Omicron variant in Southern Africa

A new study has focused on the genomic profile and early transmission dynamics of Omicron. This study revealed the dominance of the Omicron variant in regions with high levels of population immunity.

23 Dec 2021

Assessing the clinical severity of the SARS-CoV-2 Omicron variant

A recent preprint examines the proportion of Omicron infection and the risk of severe disease with this variant of SARS-CoV-2.

23 Dec 2021

Decline in protection against SARS-CoV-2 Omicron in prior infected and fully vaccinated

In a recent study posted to the medRxiv* preprint server, researchers investigated the distribution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta and Omicron variants among coronavirus disease 2019 (COVID-19) positive individuals who were either naive, fully vaccinated, or had a previous infection to further investigate possible escape from vaccine- or infection-induced immunity by Omicron compared to Delta.

22 Dec 2021

Gene News and Research

Latest Gene News and Research

Study suggests saliva swabs may be more suitable for omicron detection

Human iPSC-derived fallopian tube organoids reveal the origins of common ovarian cancer

New study targets the methylation profile of microglia from human brain

Structural blueprint of nanoparticles developed to target neutrophils responsible for acute lung inflammation

Excessive intake of simple sugar in adolescents could be a risk factor of psychiatric disorders

APOE4 allele gene linked to increased risk of severe COVID-19

LJI researchers discover how loss of TET enzymes can lead to B cell lymphoma

Single-patient pilot study shows the ability of antisense oligonucleotide to suppress mutant ALS gene

Alpha variant of SARS-CoV-2 evolved mutations to evade the immune system

Are our bowel habits written in our DNA?

Recently evolved region of the ‘dark genome’ provides clues to treatment of schizophrenia, bipolar disorder

Omicron has enhanced infectivity that is only weakly neutralized by vaccination or prior infection

Blocking function of a blood-clotting protein may help prevent or treat periodontal disease

New insights into how red meat-rich diet increases cardiovascular disease risk

Impact of the rapid spread of the SARS-CoV-2 Omicron variant in Southern Africa

Assessing the clinical severity of the SARS-CoV-2 Omicron variant

Decline in protection against SARS-CoV-2 Omicron in prior infected and fully vaccinated

Eating sugar is healthy for some Greenlanders with a genetic variation

Newly discovered species of Enterococcus bacteria named after the John Innes Centre

Amino acid valine plays a key role in the growth of T cell acute lymphoblastic leukemia

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging