Gene News and Research

Latest Gene News and Research

Evaluation of cross-reactive T cell responses between SARS-CoV-2 and common-cold human coronaviruses

A new study investigated SARS-CoV-2 spike protein responses targeted by cross-reactive T cells that were isolated from convalescent COVID-19 individuals along with previously uninfected donors.

25 Jan 2022

How artificial intelligence is poised to reshape medicine

In a recent review published in the journal of Nature Medicine, researchers discussed the results of a two-year weekly effort to track and communicate significant developments in medical (artificial intelligence) AI. They included prospective studies as well as developments in medical image analysis that have narrowed the gap between research and implementation.

24 Jan 2022

In Portugal risk of hospitalization from Omicron is 75% lower than Delta

Researchers from Portugal reported a 75% risk reduction in hospitalizations for individuals infected with Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared to the Delta variant and a shorter length of stay and lower mortality if hospitalization does occur. Their paper is currently available on the medRxiv* preprint server while undergoing peer review.

24 Jan 2022

Low-cost test could open new avenues for earlier diagnosis, treatment of rare genetic disorders

A newly developed test to screen for three rare genetic disorders simultaneously in newborns was feasible, reliable and scalable, according to a new study.

24 Jan 2022

Common cystic fibrosis drugs work by directly aiding the protein folding process, study shows

Protein misfolding is a likely culprit in many degenerative disorders. Cystic fibrosis, for instance, is caused by mutations in the CFTR gene that prevent the eponymous protein from assuming its proper configuration.

24 Jan 2022

Novel experimental drug designed to silence FUS gene may help treat ALS

Using an experimental drug, researchers were able to suppress a mutated amyotrophic lateral sclerosis (ALS) gene.

24 Jan 2022

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)."

24 Jan 2022

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

In a new study, researchers evaluated the single-cell transcriptomes from bronchiolar lavage in three adult cohorts comprising of obese and non-obese SARS-CoV-2 patients.

24 Jan 2022

Novel gene therapy for diseased muscle fiber repair

In this interview, News-Medical speaks to Dr. Jyoti K. Jaiswal about his latest research into gene therapies for limb-girdle muscular dystrophy 2B.

24 Jan 2022

Short- and long-term systemic responses in the golden hamster following SARS-CoV-2 or influenza A virus infection

A group of researchers used the golden hamster as a model system to better understand the long-term impacts of SARS-CoV-2 infection.

24 Jan 2022

Impact of clustered mutations in SARS-CoV-2 Omicron spike function

In a new study, researchers explored the characteristics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern (VOC) Omicron BA.1 sublineage clustered mutations.

24 Jan 2022

Characterization of unique pathogenesis of SARS-CoV-2 Delta variant in mouse model

Researchers have investigated the pathology and inflammatory response to the Delta variant in mice.

24 Jan 2022

Alpaca-derived antibody fragment disrupts interaction between SARS-CoV-2 spike protein and human ACE2

Researchers have been investigating the potential for using nanobodies – special immune particles from llamas and alpacas – against the disease.

24 Jan 2022

Gene replacement therapy could help mend a broken heart, study suggests

How can you mend a broken heart? According to researchers from Japan, in some cases gene replacement therapy just might do the trick.

24 Jan 2022

Researchers find ELF5 gene a leading candidate behind severe COVID-19

Are there any risk factors that predispose patients to severe COVID-19 outcomes? A recent study published in the medRxiv* preprint server sheds light on this popular question. Using a combination of population genetics to single-cell RNA sequencing, European researchers identified the respiratory epithelial cell-specific ELF5 gene as a potential mediator for severe COVID-19 cases.

24 Jan 2022

Gene News and Research

Latest Gene News and Research

Evaluation of cross-reactive T cell responses between SARS-CoV-2 and common-cold human coronaviruses

How artificial intelligence is poised to reshape medicine

In Portugal risk of hospitalization from Omicron is 75% lower than Delta

Low-cost test could open new avenues for earlier diagnosis, treatment of rare genetic disorders

Common cystic fibrosis drugs work by directly aiding the protein folding process, study shows

Novel experimental drug designed to silence FUS gene may help treat ALS

Researchers develop a computational approach to identify genomic safe harbors for therapeutic genes

Attenuated tissue immune responses against SARS-CoV-2 in obese and non-obese patients

Novel gene therapy for diseased muscle fiber repair

Short- and long-term systemic responses in the golden hamster following SARS-CoV-2 or influenza A virus infection

Impact of clustered mutations in SARS-CoV-2 Omicron spike function

Characterization of unique pathogenesis of SARS-CoV-2 Delta variant in mouse model

Alpaca-derived antibody fragment disrupts interaction between SARS-CoV-2 spike protein and human ACE2

Gene replacement therapy could help mend a broken heart, study suggests

Researchers find ELF5 gene a leading candidate behind severe COVID-19

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

Genetic marker linked to higher risk of death in COVID-19 patients

Novel SARS-CoV-2 mutations reported in chronic HIV patients

SARS-CoV-2 Omicron associated with fewer lower and more upper respiratory tract symptoms

Study finds more than 1,000 gene-activation differences between female and male mouse brains

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research