Gene News and Research

Latest Gene News and Research

Novel long-read sequencing reveals complete repertoire of brain-expressed gene isoforms

New research led by the University of Exeter has shed light on the complexity of gene expression in the brain by characterizing the extent of isoform diversity in the human and mouse cortex, including the identification of novel isoforms of genes involved in diseases including Alzheimer's disease, autism and schizophrenia.

16 Nov 2021

Scientists identify new gene that contributes to type 1 diabetes progression

When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.

16 Nov 2021

Two genetic risk variants in Black individuals may exacerbate sepsis and COVID-19 severity

Two genetic risk variants that are carried by nearly 40 percent of Black individuals may exacerbate the severity of both sepsis and COVID-19, a team of researchers from the University of Pennsylvania's Perelman School of Medicine have found.

16 Nov 2021

Identification of transcription regulatory sequences and genes in previously unannotated coronaviruses

Scientists have hypothesized that the presence of regulatory sequences could be effectively used to instantaneously and accurately identify TRS sites as well as the related viral genes in unannotated coronavirus genomes.

16 Nov 2021

Rapid thermal cycling approach for the detection of SARS-CoV-2

Researchers develop an ultrafast detection method for SARS-CoV-2 by direct RT-PCR without RNA extraction that is suitable for large-scale use.

15 Nov 2021

Histone mimicry as a mechanism through which SARS-CoV-2 disrupts host cell epigenetic regulation

A recent study investigates histone mimicry as a mechanism by SARS-CoV-2 for disrupting epigenetic regulation to evade host cell responses to infection.

15 Nov 2021

Study offers new insight into the role of tau proteins in ALS pathogenesis

A team led by investigators at Massachusetts General Hospital has shown that people living with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, who carry a mutation in the C9orf72 gene exhibit elevated levels of tau and phosphorylated tau protein in the motor cortex region of the brain.

15 Nov 2021

Stem cell treatment reduced deaths related to cardiovascular issues, not hospitalization

Stem cell therapy helped to reduce the number of heart attacks, strokes and death among people with chronic, high-risk, NYHA class II or III heart failure with reduced ejection fraction (HFrEF), especially among those who have higher levels of inflammation, yet hospitalization was not reduced, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2021.

15 Nov 2021

Lamin C important for keeping cell’s genetic material organized, research shows

In a study with lab-grown mouse cells, Johns Hopkins Medicine researchers say they have found that a protein that helps form a structural network under the surface of the cell's "command center" — its nucleus — is key to ensuring that DNA inside it remains orderly.

15 Nov 2021

Researchers discover new gene critical for daily behavioral rhythms

Life is organized on a 24-hour schedule. Central to this regular rhythm is the circadian clock, timekeepers that are present in virtually every organ, tissue and cell type. When a clock goes awry, sleep disruption or a variety of diseases can result.

15 Nov 2021

Research expands the general understanding of transcription process in bacteria

Bacteria need to constantly adapt to compete against other species for nutrient sources and to survive against threats such as antibiotics and toxins.

15 Nov 2021

SARS-CoV-2 infection inhibited by CCR2 signaling

A new study discusses the role of monocytes in protecting individuals from SARS-CoV-2.

15 Nov 2021

Standard PCR tests do not pick up new Covid strains, warns expert

Some new strains of Covid-19 are not being picked up by standard PCR tests, reveals leading testing expert Dr Quinton Fivelman. He warns that new mutations mean some variants are not being picked up by the standard, widely-used, single gene tests.

15 Nov 2021

Study provides a new target for therapeutic intervention in Parkinson's disease

In an unexpected discovery, Georgetown University Medical Center researchers have identified what appears to be a significant vascular defect in patients with moderately severe Parkinson's disease.

14 Nov 2021

Scientists develop a single-cell chromatin atlas for the human genome

Researchers at University of California San Diego have produced a single-cell chromatin atlas for the human genome.

14 Nov 2021

£375 million Government funding to improve treatment for neurodegenerative diseases

People living with neurodegenerative diseases could live longer, healthier lives due to innovative new research, following a government commitment to invest £375 million over the next 5 years.

14 Nov 2021

New evidence reveals a cancer-promoting role for MAPK6 enzyme

A team led by scientists at Baylor College of Medicine uncovered new evidence supporting a cancer-promoting role for enzyme MAPK6.

12 Nov 2021

Advanced technique reveals the ultrastructure of huntingtin inclusion bodies

Huntington's disease is a progressively debilitating brain disease that causes uncontrolled movements, psychological problems, and loss of cognition.

12 Nov 2021

GPR126 gene may play an essential role in placental development, study reveals

Scientists working with an experimental mouse model at the Centro Nacional de Investigaciones Cardiovasculares have identified the essential role of the gene GPR126 in the development of the placenta during pregnancy.

12 Nov 2021

Rare disease diagnosis by 100,000 genomes pilot

A team of researchers conducted a pilot study that enrolled families and undertook detailed clinical phenotyping of the proband to evaluate the effect of the whole genome sequencing approach on a genetic diagnosis of rare conditions by the NHS in the UK.

12 Nov 2021

Gene News and Research

Latest Gene News and Research

Novel long-read sequencing reveals complete repertoire of brain-expressed gene isoforms

Scientists identify new gene that contributes to type 1 diabetes progression

Two genetic risk variants in Black individuals may exacerbate sepsis and COVID-19 severity

Identification of transcription regulatory sequences and genes in previously unannotated coronaviruses

Rapid thermal cycling approach for the detection of SARS-CoV-2

Histone mimicry as a mechanism through which SARS-CoV-2 disrupts host cell epigenetic regulation

Study offers new insight into the role of tau proteins in ALS pathogenesis

Stem cell treatment reduced deaths related to cardiovascular issues, not hospitalization

Lamin C important for keeping cell’s genetic material organized, research shows

Researchers discover new gene critical for daily behavioral rhythms

Research expands the general understanding of transcription process in bacteria

SARS-CoV-2 infection inhibited by CCR2 signaling

Standard PCR tests do not pick up new Covid strains, warns expert

Study provides a new target for therapeutic intervention in Parkinson's disease

Scientists develop a single-cell chromatin atlas for the human genome

£375 million Government funding to improve treatment for neurodegenerative diseases

New evidence reveals a cancer-promoting role for MAPK6 enzyme

Advanced technique reveals the ultrastructure of huntingtin inclusion bodies

GPR126 gene may play an essential role in placental development, study reveals

Rare disease diagnosis by 100,000 genomes pilot

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