Gene News and Research

Latest Gene News and Research

Scientists identify molecular mechanism behind weight gain in patients taking antipsychotics

Scientists with UT Southwestern's Peter O'Donnell Jr. Brain Institute have identified the molecular mechanism that can cause weight gain for those using a common antipsychotic medication.

12 May 2021

CNIO researchers unravel why motor neurons die in ALS patients

In Amyotrophic Lateral Sclerosis (ALS), the progressive death of neurons that control body movement leads to paralysis of muscles in the limbs and gradually of the whole body, which ultimately makes it impossible to breathe. ALS is currently untreatable, and its cause is unknown.

12 May 2021

Investment in primary prevention can reduce rheumatic heart disease in the African Union

Rheumatic heart disease (RHD) remains a major cause of cardiovascular disease in Africa, even as acute rheumatic fever and RHD have become rare in high-income countries.

12 May 2021

Investigational gene therapy can restore immune function in children with inherited immunodeficiency disorder

An investigational gene therapy can safely restore the immune systems of infants and children who have a rare, life-threatening inherited immunodeficiency disorder, according to research supported in part by the National Institutes of Health.

12 May 2021

Researchers conduct first-in-man clinical trial for new stem cell technology

Institutes and centres under the SingHealth Duke-NUS Academic Medical Centre (AMC) are joining hands together with Singapore's first private cord blood bank, Cordlife Group Limited (Cordlife), to test a novel technology that expands the number of blood-forming stem cells from stored umbilical cord blood (UCB) in a first-in-man study in Singapore.

12 May 2021

Low dose of a four-drug combination helps prevent cancer metastasis in mice

Low doses of a four-drug combination helps prevent the spread of cancer in mice without triggering drug resistance or recurrence, shows a study published today in eLife.

11 May 2021

Personalized vaccine can provide effective immunization against cancer

Marie-Claude Bourgeois-Daigneault and her team at the CRCHUM are using mice to show how a combination of peptides and oncolytic viruses, used as an adjuvant, can provide effective immunization against cancer.

11 May 2021

Novel 'CopyCatcher' detects when precise copying of genetic information takes place in cells

Researchers at the University of California San Diego have laid the groundwork for a potential new type of gene therapy using novel CRISPR-based techniques.

11 May 2021

Experimental gene therapy successfully treats children born without an immune system

An experimental form of gene therapy developed by a team of researchers from UCLA and Great Ormond Street Hospital in London has successfully treated 48 of 50 children born with a rare and deadly inherited disorder that leaves them without an immune system.

11 May 2021

MIT researchers generate the complete gene annotation of SARS-CoV-2 genome

In early 2020, a few months after the Covid-19 pandemic began, scientists were able to sequence the full genome of the virus that causes the infection, SARS-CoV-2. While many of its genes were already known at that point, the full complement of protein-coding genes was unresolved.

11 May 2021

New tool may safely block gene linked to factors that cause heart disease

Looking to safely block a gene linked to factors known to cause heart disease, scientists at the University of Colorado Anschutz Medical Campus may have found a new tool - light.

11 May 2021

Severe COVID-19 linked to genetic clotting predisposition

Thus, the need to stratify the risk of severe or critical disease in patients presenting with SARS-CoV-2 infection remains a crying necessity. A new preprint research paper posted to the medRxiv server discusses the relationship between severe disease and pre-existing susceptibility to clots and other diseases of the cardiovascular system.

11 May 2021

Machine learning approach helps study human hypothalamus at the single-cell level

Human brain organoids are remarkable platforms for modeling features of human brain development and diseases.

11 May 2021

New approach combines molecular and medical imaging data to diagnose cancer type

Despite our remarkable advances in medicine and healthcare, the cure to cancer continues to elude us. On the bright side, we have made considerable progress in detecting several cancers in earlier stages, allowing doctors to provide treatments that increase long-term survival.

11 May 2021

Researchers explore effects of reduced gravity on mouse skeletal muscles

Most of us have imagined how free it would feel to float around, like an astronaut, in conditions of reduced gravity. But have you ever considered what the effects of reduced gravity might have on muscles?

11 May 2021

Natural products a rich source for novel antiviral compounds

In a recent review in the journal Viruses, researchers look at natural products that can be identified as potential alternative antiviral agents. The reviewers discussed the antiviral activities of several natural products towards DNA and RNA viruses with an analytical approach. The researchers detailed the cellular/viral targets of the active molecules and their impact on the infection and viral replication cycle.

10 May 2021

Gene News and Research

Latest Gene News and Research

Scientists identify molecular mechanism behind weight gain in patients taking antipsychotics

CNIO researchers unravel why motor neurons die in ALS patients

Investment in primary prevention can reduce rheumatic heart disease in the African Union

Investigational gene therapy can restore immune function in children with inherited immunodeficiency disorder

Researchers conduct first-in-man clinical trial for new stem cell technology

Low dose of a four-drug combination helps prevent cancer metastasis in mice

Personalized vaccine can provide effective immunization against cancer

Novel 'CopyCatcher' detects when precise copying of genetic information takes place in cells

Experimental gene therapy successfully treats children born without an immune system

MIT researchers generate the complete gene annotation of SARS-CoV-2 genome

New tool may safely block gene linked to factors that cause heart disease

Severe COVID-19 linked to genetic clotting predisposition

Machine learning approach helps study human hypothalamus at the single-cell level

New approach combines molecular and medical imaging data to diagnose cancer type

Researchers explore effects of reduced gravity on mouse skeletal muscles

Natural products a rich source for novel antiviral compounds

Machine learning technique detects epigenetic drivers of cancers

Rice University neurobiologist wins NIH grant to study enteric nervous system development

Normalizing cholesterol metabolism in microglia alleviates chronic neuropathic pain

Esophageal cancers turn on ancient viral DNA hidden in our genome

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging