Gene News and Research

Latest Gene News and Research

Researchers gain new insights into the pathology of Usher syndrome

Human Usher syndrome (USH) is the most common form of hereditary deaf-blindness. Sufferers can be deaf from birth, suffer from balance disorders, and eventually lose their eyesight as the disease progresses.

12 Jul 2021

Researchers discover new genetic driver of autism and other developmental disorders

A research group including Kobe University's Professor TAKUMI Toru (also a Senior Visiting Scientist at RIKEN Center for Biosystems Dynamics Research) and Assistant Professor TAMADA Kota, both of the Physiology Division in the Graduate School of Medicine, has revealed a causal gene (Necdin, NDN) in autism model mice that have the chromosomal abnormality called copy number variation.

9 Jul 2021

Malfunction in the cell’s powerhouse causes sporadic Parkinson disease

The major cause of Parkinson’s Disease is a dysregulation of immune genes central for fighting against viruses, a new study reveals.

9 Jul 2021

Mating can turn off a single gene for multiple generations, study shows

Evidence suggests that what happens in one generation--diet, toxin exposure, trauma, fear--can have lasting effects on future generations.

9 Jul 2021

Metabolites of intestinal bacteria can positively influence the efficacy of tumor therapies

Certain metabolites of bacteria from the intestine make immune cells more aggressive as a new study conducted by scientists from Würzburg and Marburg reveals. The findings could help improve cancer therapies.

9 Jul 2021

Doctors weigh pros and cons of prescribing hot-button Alzheimer’s drug

As physicians and health policy experts debate the merits of Aduhelm, the first new drug for Alzheimer's disease approved in 18 years, patients want to know: "Will this medication help me — and how much?"

9 Jul 2021

Breakthrough SARS-CoV-2 infection among fully vaccinated likely to be less transmissible

Researchers in the United States have conducted a study suggesting that individuals fully vaccinated against coronavirus disease 2019 (COVID-19) who develop breakthrough infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are less likely to transmit the virus to others than unvaccinated infected individuals.

8 Jul 2021

Researchers identify potential new treatment targets for Alzheimer's disease

A research team at Washington University School of Medicine in St. Louis has identified potential new treatment targets for Alzheimer's disease, as well as existing drugs that have therapeutic potential against these targets.

8 Jul 2021

Scientists discover potential marker for the success of immunotherapy in lung cancer patients

Lung cancer has the highest mortality rate of all cancers, and treatment options are extremely limited, especially for patients with oncogenic mutations in the KRAS gene.

8 Jul 2021

Researchers uncover genetic markers associated with COVID-19 infection risk and severity

An international collaboration uncovers several genetic markers associated with SARS-CoV-2 infection and COVID-19 severity.

8 Jul 2021

Study uncovers mutations in Polycomb group gene as underlying cause of novel neurological disorder

A multi-institutional study has discovered spontaneous mutations in RNF2 (RING2) gene as the underlying cause of a novel neurological disorder.

8 Jul 2021

B.1.1.7 variant of SARS-CoV-2 is more transmissible than B.1.526

A new paper available on the medRxiv* preprint server presents evidence that the B.1.1.7 VOC is more transmissible than the B.1.526 strain.

7 Jul 2021

An antioxidative stress regulator helps keep muscles from becoming weak in low gravity

Most kids dream of growing up to be astronauts; but the downside of spending extended amounts of time in low gravity is that astronauts' muscles tend to shrink and weaken through disuse. Now, researchers from Japan have identified a protein that affects how muscles respond to space flight.

7 Jul 2021

Study: Gene editing therapy for early-stage Huntington’s disease may have long-lasting benefits

In a new study on mice, Johns Hopkins Medicine researchers report that using MRI scans to measure blood volume in the brain can serve as a noninvasive way to potentially track the progress of gene editing therapies for early-stage Huntington's disease, a neurodegenerative disorder that attacks brain cells.

7 Jul 2021

Rare genetic variants have a big impact on the risk of developing type 2 diabetes

Scientists at the University of Cambridge have identified rare genetic variants - carried by one in 3,000 people - that have a larger impact on the risk of developing type 2 diabetes than any previously identified genetic effect.

7 Jul 2021

Researchers identify early functional deficiencies in neurons derived from Parkinson's patients

Researchers from IDIBELL and the University of Barcelona have described that neurons derived from Parkinson's patients show impairments in their transmission before neurodegeneration.

7 Jul 2021

Study addresses potential interrelations between AID/APOBECs and the SARS-CoV-2 virus

Together with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called APOBEC proteins are important factors in the body's immune response and offer fast and effective protection against a large number of DNA and RNA viruses.

7 Jul 2021

Study identifies specialized immune cells that sculpt inhibitory neurons to regulate brain wiring

From the bark of a puppy to the patter of rain against the window, our brains receive countless signals every second. Most of the time, we tune out inconsequential cues--the buzz of a fly, the soft rustle of leaves in the tree--and pay attention to important ones--the sound of a car horn, a bang on the door.

7 Jul 2021

Research shows how loss of de-N-glycosylation enzyme causes detrimental effects

Peptide: N-glycanase (NGLY1) is an evolutionarily conserved enzyme for removing N-linked glycans (N-glycans) from glycoproteins and is involved in proteostasis of N-glycoproteins in the cytosol. In 2012, a rare genetic disorder called NGLY1 deficiency was discovered by an exome analysis.

7 Jul 2021

Uncovering cellular mechanism related to gene silencing therapies

Gene silencing therapies are used to interfere with, or "silence", the expression of genes that are associated with disorders. Now, a team at TMDU has uncovered some of the cellular mechanisms by which the silencing therapies act in cells.

7 Jul 2021

Gene News and Research

Latest Gene News and Research

Researchers gain new insights into the pathology of Usher syndrome

Researchers discover new genetic driver of autism and other developmental disorders

Malfunction in the cell’s powerhouse causes sporadic Parkinson disease

Mating can turn off a single gene for multiple generations, study shows

Metabolites of intestinal bacteria can positively influence the efficacy of tumor therapies

Doctors weigh pros and cons of prescribing hot-button Alzheimer’s drug

Breakthrough SARS-CoV-2 infection among fully vaccinated likely to be less transmissible

Researchers identify potential new treatment targets for Alzheimer's disease

Scientists discover potential marker for the success of immunotherapy in lung cancer patients

Researchers uncover genetic markers associated with COVID-19 infection risk and severity

Study uncovers mutations in Polycomb group gene as underlying cause of novel neurological disorder

B.1.1.7 variant of SARS-CoV-2 is more transmissible than B.1.526

An antioxidative stress regulator helps keep muscles from becoming weak in low gravity

Study: Gene editing therapy for early-stage Huntington’s disease may have long-lasting benefits

Rare genetic variants have a big impact on the risk of developing type 2 diabetes

Researchers identify early functional deficiencies in neurons derived from Parkinson's patients

Study addresses potential interrelations between AID/APOBECs and the SARS-CoV-2 virus

Study identifies specialized immune cells that sculpt inhibitory neurons to regulate brain wiring

Research shows how loss of de-N-glycosylation enzyme causes detrimental effects

Uncovering cellular mechanism related to gene silencing therapies

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research