Gene News and Research

Latest Gene News and Research

Japanese–European scientists detect novel genetic mitochondrial disorder

The list of known genetic mitochondrial disorders is ever-growing, and ongoing research continues to identify new disorders in this category.

15 Apr 2021

CityU researchers identify super-enhancers that stimulate the activity of breast cancer genes

Triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with a high fatality rate. Currently, chemotherapy is the major treatment option, but the clinical result is unsatisfactory.

15 Apr 2021

Anti-diabetic drug metformin inhibits disease progression in Alport syndrome mouse model

Researchers from Kumamoto University have found that the anti-diabetic drug metformin significantly prolongs the survival of mice in a model that simulates the pathology of non-diabetic chronic kidney disease (ND-CKD) by ameliorating pathological conditions like reduced kidney function, glomerular damage, inflammation and fibrosis.

15 Apr 2021

New machine learning method for designing more effective antibody drugs

Antibodies are not only produced by our immune cells to fight viruses and other pathogens in the body. For a few decades now, medicine has also been using antibodies produced by biotechnology as drugs.

15 Apr 2021

Keele researcher awarded prestigious grant to identify treatments for devastating childhood disease

A Keele researcher will embark on a two-year study to identify affordable treatments to help children living with spinal muscular atrophy.

15 Apr 2021

Can biomaterials offer novel therapeutic strategies against COVID-19?

A team of scientists reviews the current and potential impact of the biomaterial sciences on the COVID-19 pandemic.

15 Apr 2021

Study reveals how DNA segments function in cells

A new study co-authored by University of Colorado Cancer Center researcher Srinivas Ramachandran, PhD, shows how DNA segments known as enhancers function in cells.

15 Apr 2021

Study may lead to new therapies for patients suffering from Duchenne muscular dystrophy

A new study, led by the University of California, Irvine (UCI), reveals how chronic inflammation promotes muscle fibrosis, which could inform the development of new therapies for patients suffering from Duchenne muscular dystrophy (DMD), a fatal muscle disease.

15 Apr 2021

Study may lead to new treatment for incurable brain cancer in children

Research by Australian scientists could pave the way to a new treatment for a currently incurable brain cancer in children called Diffuse Intrinsic Pontine Glioma, or DIPG. Affecting about 20 children in Australia each year, DIPG is a devastating disease with an average survival time of just nine months after diagnosis.

15 Apr 2021

Malaria mutations may be gaining a foothold in Africa, shows new data

New data provide the first clinical evidence that drug-resistant mutations in the malaria parasite Plasmodium falciparum may be gaining a foothold in Africa.

15 Apr 2021

Experts to discuss advanced cancer cell and gene therapies at Summit 2021

April 29 marks a pivotal moment in cancer research when the world's brightest minds come together to discuss how to translate the success of CAR T-cell therapies for blood cancers into successful cell and gene therapies for the most complex and deadly solid tumor cancers.

15 Apr 2021

Researchers identify long-sought enzyme that prevents cancer

Researchers have found a long-sought enzyme that prevents cancer by enabling the breakdown of proteins that drive cell growth, and that causes cancer when disabled.

14 Apr 2021

Ponatinib identified as a potent inhibitor of SARS-CoV2-induced cytokine storm

Researchers at the Human Biology Division, Fred Hutchinson Cancer Research Center in Washington, United States, found that the FDA-approved, multi-kinase inhibitor Ponatinib is a potent inhibitor of the N-terminal domain (NTD) -mediated cytokine storm. Ponatinib is an oral drug used for the treatment of chronic myeloid leukemia (CML).

14 Apr 2021

Study offers a non-invasive avenue for monitoring buildings for COVID-19 outbreaks

A study done in rooms where COVID-19 patients were isolated shows that the virus's RNA - part of the genetic material inside a virus - can persist up to a month in dust.

13 Apr 2021

Mouse model closely replicates human NAFLD

Human non-alcoholic fatty liver disease (NAFLD) is a little-understood condition that significantly increases the risk of inflammation, fibrosis and liver cancer and ultimately requires liver transplant.

13 Apr 2021

Researchers discover molecular signatures of aging process in mice

Researchers have identified molecular signatures of the aging process in mice, publishing their results today in the open-access eLife journal.

13 Apr 2021

Aged bone marrow niche restrains function of rejuvenated HSCs, shows study

When leukemia strikes an older person, it is in part due to the aging of his or her hematopoietic stem cells (HSCs).

13 Apr 2021

Altering a mosquito's gut genes shows promise to curb malaria

Altering a mosquito's gut genes to make them spread antimalarial genes to the next generation of their species shows promise as an approach to curb malaria, suggests a preliminary study published today in eLife.

13 Apr 2021

Biology of single-celled organisms reveals potential treatment target for COPD

In a series of experiments that began with amoebas -- single-celled organisms that extend podlike appendages to move around -- Johns Hopkins Medicine scientists say they have identified a genetic pathway that could be activated to help sweep out mucus from the lungs of people with chronic obstructive pulmonary disease a widespread lung ailment.

13 Apr 2021

Gene therapy may offer a new approach to preserving vision in people with retinitis pigmentosa

A gene therapy protects eye cells in mice with a rare disorder that causes vision loss, especially when used in combination with other gene therapies, shows a study published today in eLife.

13 Apr 2021

Gene News and Research

Latest Gene News and Research

Japanese–European scientists detect novel genetic mitochondrial disorder

CityU researchers identify super-enhancers that stimulate the activity of breast cancer genes

Anti-diabetic drug metformin inhibits disease progression in Alport syndrome mouse model

New machine learning method for designing more effective antibody drugs

Keele researcher awarded prestigious grant to identify treatments for devastating childhood disease

Can biomaterials offer novel therapeutic strategies against COVID-19?

Study reveals how DNA segments function in cells

Study may lead to new therapies for patients suffering from Duchenne muscular dystrophy

Study may lead to new treatment for incurable brain cancer in children

Malaria mutations may be gaining a foothold in Africa, shows new data

Experts to discuss advanced cancer cell and gene therapies at Summit 2021

Researchers identify long-sought enzyme that prevents cancer

Ponatinib identified as a potent inhibitor of SARS-CoV2-induced cytokine storm

Study offers a non-invasive avenue for monitoring buildings for COVID-19 outbreaks

Mouse model closely replicates human NAFLD

Researchers discover molecular signatures of aging process in mice

Aged bone marrow niche restrains function of rejuvenated HSCs, shows study

Altering a mosquito's gut genes shows promise to curb malaria

Biology of single-celled organisms reveals potential treatment target for COPD

Gene therapy may offer a new approach to preserving vision in people with retinitis pigmentosa

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research