Gene News and Research

Latest Gene News and Research

Novel approach to gene editing bypasses disease-causing mutations in a gene

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

21 Apr 2021

Interfering RNA nanoparticles could be a potential COVID-19 therapy

Study shows lipid nanoparticle-based siRNA is potent in suppressing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the causative agent of coronavirus disease 2019 (COVID-19) – in cells as well as in mice models.

21 Apr 2021

Researchers explore cost-effective identification method for novel SARS-CoV-2 variants

In a new study, a rapid and cost-effective method of detecting known variants of concern has been developed utilizing capillary electrophoresis, allowing local facilities to screen for and track SARS-CoV-2 variants of concern and implement reactionary procedures.

21 Apr 2021

New efforts to improve the efficacy of nucleotide-based drugs against prostate cancer, bone metastasis

Published in the Advanced Functional Materials, University of Minnesota researcher Hongbo Pang led a cross-institutional study on improving the efficacy of nucleotide-based drugs against prostate cancer and bone metastasis.

21 Apr 2021

Field of mathematics reveals a potential gene that causes acute lymphoblastic leukemia

Using a widely known field of mathematics designed mainly to study how digital and other forms of information are measured, stored and shared, scientists at Johns Hopkins Medicine and Johns Hopkins Kimmel Cancer Center say they have uncovered a likely key genetic culprit in the development of acute lymphoblastic leukemia (ALL).

21 Apr 2021

Characterization of lab-produced neutralizing antibodies targeting SARS-CoV-2

A new study led by Hans-Martin Jäck of the Friedrich-Alexander University Erlangen-Nuremberg in Germany engineered clusters of neutralizing monoclonal antibodies using a transgenic mouse model. A unique characteristic for the antibodies was the different ways it bound to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the overall reduction in the viral spread for human ACE2.

21 Apr 2021

Researchers identify the cause of severe canine juvenile epilepsy

In a study conducted at the University of Helsinki, researchers found a cause for severe epilepsy resulting in death in Parson Russell Terrier puppies at a few months of age. A change in the PITRM1 gene can lead to a dysfunction of mitochondria, the cellular energy pumps.

21 Apr 2021

Study challenges the assumption that all South African Bantu speakers are a single genetic entity

Almost 80% of South Africans speak one of the SEB family languages as their first language. Their origins can be traced to farmers of West-Central Africa whose descendants over the past two millennia spread south of the equator and finally into Southern Africa.

20 Apr 2021

Genethon announces dosing of first patient at pediatric clinical trial platform for neuromuscular diseases

A first participant was dosed at I-Motion, the pediatric clinical trial platform for neuromuscular diseases located at Trousseau hospital in Paris, as part of the gene therapy trial in Duchenne muscular dystrophy (DMD) conducted by Genethon.

20 Apr 2021

Comprehensive roadmap of muscle aging reveals potential targets for treatments

Scientists have produced a comprehensive roadmap of muscle aging in mice that could be used to find treatments that prevent decline in muscle mobility and function, according to a report published today in eLife.

20 Apr 2021

Targeted therapy may be of great benefit in early stage breast cancer

Targeted therapy in early stages of breast cancer can pave the way for a notable higher success rate, shows a study from the University of Bergen, Norway.

20 Apr 2021

Researchers develop new biomaterial that regrows blood vessels and bone

Scientists have developed a new biomaterial that regrows blood vessels and bone, potentially providing a single-stage approach when repairing large bone defects.

20 Apr 2021

Systematic review: Exposure to endocrine-disruptors could elevate breast cancer risk

Exposure to certain endocrine-disrupting chemicals could elevate the risk of breast cancer, according to a new comprehensive systematic review of epidemiological research.

20 Apr 2021

1 in 6 patients with colorectal cancer found to have inherited genetic mutations

A new Mayo Clinic study bolsters evidence that colorectal cancer is often imprinted in family genes and passed on from one generation to the next.

20 Apr 2021

Study provides the first extensive genetic and phenotype landscape of peripartum cardiomyopathy

Researchers at Penn Medicine have identified more genetic mutations that strongly predispose younger, otherwise healthy women to peripartum cardiomyopathy (PPCM), a rare condition characterized by weakness of the heart muscle that begins sometime during the final month of pregnancy through five months after delivery.

20 Apr 2021

POT1 gene linked to glioma development mediates its effects in a sex-specific manner

Researchers at Baylor College of Medicine and collaborators at other institutions have discovered that POT1, a gene known to be associated with risk of glioma, the most common type of malignant brain tumor, mediates its effects in a sex-specific manner.

20 Apr 2021

Gene News and Research

Latest Gene News and Research

Novel approach to gene editing bypasses disease-causing mutations in a gene

Interfering RNA nanoparticles could be a potential COVID-19 therapy

Researchers explore cost-effective identification method for novel SARS-CoV-2 variants

New efforts to improve the efficacy of nucleotide-based drugs against prostate cancer, bone metastasis

Field of mathematics reveals a potential gene that causes acute lymphoblastic leukemia

Characterization of lab-produced neutralizing antibodies targeting SARS-CoV-2

Researchers identify the cause of severe canine juvenile epilepsy

Study challenges the assumption that all South African Bantu speakers are a single genetic entity

Genethon announces dosing of first patient at pediatric clinical trial platform for neuromuscular diseases

Comprehensive roadmap of muscle aging reveals potential targets for treatments

Targeted therapy may be of great benefit in early stage breast cancer

Researchers develop new biomaterial that regrows blood vessels and bone

Systematic review: Exposure to endocrine-disruptors could elevate breast cancer risk

1 in 6 patients with colorectal cancer found to have inherited genetic mutations

Study provides the first extensive genetic and phenotype landscape of peripartum cardiomyopathy

POT1 gene linked to glioma development mediates its effects in a sex-specific manner

Scientists identify protein that operates closely with a genetic mutation to spur lung cancer growth

Study reveals why intellectual disability risk for younger siblings is low

Simple dietary supplement ameliorates schizophrenic traits in mice

Topical drug regenerates, restores function of erectile nerves damaged by radical prostatectomy

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research