Gene News and Research

Latest Gene News and Research

Inflammation may contribute to the persistence of C. diff infection, shows study

A new study from North Carolina State University shows that the inflammation caused by Clostridioides difficile (C. diff) infection gives the pathogen a two-fold advantage: by both creating an inhospitable environment for competing bacteria and providing nutrients that enable C. diff to thrive.

19 Jan 2021

Research finds new evidence about the mechanisms controlling skin repair and regeneration

As the air continues to dry and temperatures drop, the yearly battle against dry hands and skin has officially begun. New research from Northwestern University has found new evidence deep within the skin about the mechanisms controlling skin repair and renewal.

19 Jan 2021

Researchers identify new drug combination that can treat acute myeloid leukemia

Scientists have identified two drugs that are potent against acute myeloid leukemia (AML) when combined, but only weakly effective when used alone.

19 Jan 2021

New method could provide additional insight into brain tumors

A look at RNA tells us what our genes are telling our cells to do, and scientists say looking directly at the RNA of brain tumor cells appears to provide objective, efficient evidence to better classify a tumor and the most effective treatments.

19 Jan 2021

Genomics reveals distinct patterns of emergence of SARS‐CoV‐2 spike variants in Columbus, Ohio

Recently researchers from the United States reported the results of a SARS‐CoV‐2 genomic surveillance conducted between April 2020 and January 2021 in Columbus, Ohio. Their work is released as a preprint on the bioRxiv server.

18 Jan 2021

About 60 percent of SARS-CoV-2 cases in England tied to new variant by the end of December

One new SARS-CoV-2 variant of concern, called 202012/01, started to spread in England in late October. A new study published on the pre-print server medRxiv found that 60 percent of daily COVID-19 cases screened by the Alderley Park Lighthouse Labs were tied to 202012/01, also known as lineage B.1.1.7 or 20B/501Y.V1. This suggests a rapid spread of the new variant across the country.

18 Jan 2021

Researchers define tumor invasion machinery orchestrated by a master cancer gene

Researchers investigated how cancer genes lead to the breakdown of the capsule that prevents cancerous cells from invading the surrounding healthy tissues and - find a hijacked "molecular crowbar".

18 Jan 2021

Study finds new evidence about the positive role of androgens in breast cancer treatment

Researchers at the University of Adelaide have found new evidence about the positive role of androgens in breast cancer treatment with immediate implications for women with estrogen receptor-driven metastatic disease.

18 Jan 2021

New computational technique accurately differentiates between data from tumor cells and normal cells

In an effort to address a major challenge when analyzing large single-cell RNA-sequencing datasets, researchers from The University of Texas MD Anderson Cancer Center have developed a new computational technique to accurately differentiate between data from cancer cells and the variety of normal cells found within tumor samples.

18 Jan 2021

New SARS-CoV-2 variant emerges in the U.S.

Even as the rollout of vaccines all over the world brings a glimmer of hope that the current coronavirus disease 2019 (COVID-19) pandemic may end in the near future, new variants continue to emerge, some with the potential to escape vaccine-induced or therapeutic antibodies. Now, a new preprint research paper published on the bioRxiv server describes a new American variant that may have become the dominant strain in the USA.

18 Jan 2021

Mothers of children with autism have many significantly different metabolite levels, study finds

Now, a study by researchers at the Rensselaer Polytechnic Institute, Arizona State University, and the Mayo Clinic found that mothers of children with autism spectrum disorder had several marked different metabolite levels two to five years after they gave birth compared to mothers of normally developing children.

17 Jan 2021

Research suggests St. John's Wort and Echinacea could protect against COVID-19

Researchers in Saudi Arabia have conducted a study demonstrating the antiviral effects of two medicinal herbs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

17 Jan 2021

New therapeutic approach enables functional recovery after spinal cord injury in mice

Using gene therapy, a research team has succeeded for the first time in getting mice to walk again after a complete cross-sectional injury. The nerve cells produced the curative protein themselves.

16 Jan 2021

Study: NTRK fusions are far more frequently seen in pediatric tumors

In a large study of pediatric cancer patients, researchers from Children's Hospital of Philadelphia have analyzed the frequency, fusion partners, and clinical outcome of neurotrophic tyrosine receptor kinase (NTRK) fusions, which are clinical biomarkers that identify patients suitable for treatment with FDA-approved TRK inhibitors.

16 Jan 2021

Study reveals significant role of ADAMTS1 protein in uveal melanoma

Scientists from the University of Granada and GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research), in a study led by Juan Carlos Rodríguez-Manzaneque, have demonstrated the significant role of a protein called ADAMTS1 in uveal melanoma, one of the rarest and most aggressive cancers that exist, which develops in the eye.

15 Jan 2021

Myelin‐specific T cells implicated in central nervous system disease in monkeys

Scientists have uncovered new clues implicating a type of herpes virus as the cause of a central nervous system disease in monkeys that's similar to multiple sclerosis in people.

15 Jan 2021

Researchers discover unexpected role for the clock gene in prostate cancer progression

Our biological or circadian clock synchronizes all our bodily processes to the natural rhythms of light and dark. It's no wonder then that disrupting the clock can wreak havoc on our body.

15 Jan 2021

New tests may help reveal the transcriptome of SARS-CoV-2 and predict disease course

As the COVID-19 pandemic continues to infect people in their hundreds of thousands around the world, a new study describes a panel of novel tests for genomic (g) and subgenomic (sg) mRNAs generated by SARS-CoV-2. Most assays in use at present are either qualitative or semi-quantitative, and cannot evaluate the transcription molecules in detail.

14 Jan 2021

EGR1 protein acts as a master regulator of inflammation in macrophages, study suggests

Scientists at The Wistar Institute discovered that Early Growth Response 1 (EGR1), a protein that turns on and off specific genes during blood cell development, inhibits expression of pro-inflammatory genes in macrophages.

14 Jan 2021

Researchers develop a tiny, yet effective method for preventing premature birth

In a study in mice and human cells, Johns Hopkins Medicine researchers say that they have developed a tiny, yet effective method for preventing premature birth.

13 Jan 2021

Gene News and Research

Latest Gene News and Research

Inflammation may contribute to the persistence of C. diff infection, shows study

Research finds new evidence about the mechanisms controlling skin repair and regeneration

Researchers identify new drug combination that can treat acute myeloid leukemia

New method could provide additional insight into brain tumors

Genomics reveals distinct patterns of emergence of SARS‐CoV‐2 spike variants in Columbus, Ohio

About 60 percent of SARS-CoV-2 cases in England tied to new variant by the end of December

Researchers define tumor invasion machinery orchestrated by a master cancer gene

Study finds new evidence about the positive role of androgens in breast cancer treatment

New computational technique accurately differentiates between data from tumor cells and normal cells

New SARS-CoV-2 variant emerges in the U.S.

Mothers of children with autism have many significantly different metabolite levels, study finds

Research suggests St. John's Wort and Echinacea could protect against COVID-19

New therapeutic approach enables functional recovery after spinal cord injury in mice

Study: NTRK fusions are far more frequently seen in pediatric tumors

Study reveals significant role of ADAMTS1 protein in uveal melanoma

Myelin‐specific T cells implicated in central nervous system disease in monkeys

Researchers discover unexpected role for the clock gene in prostate cancer progression

New tests may help reveal the transcriptome of SARS-CoV-2 and predict disease course

EGR1 protein acts as a master regulator of inflammation in macrophages, study suggests

Researchers develop a tiny, yet effective method for preventing premature birth

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging