Gene News and Research

Latest Gene News and Research

Researchers describe the key facet of sexual determination in mammalian models

Early in human development, during the first trimester of gestation, a fetus may have XX or XY chromosomes that indicate its sex. Yet at this stage a mass of cells known as the bipotential gonad that ultimately develops into either ovaries or testes has yet to commit to its final destiny.

7 May 2021

Molecular clues explain why some neurons are more susceptible than others in Alzheimer’s disease

In the brain of a person with Alzheimer's disease, neurons degenerate and die, slowly eliminating memories and cognitive skills. However, not all neurons are impacted equally.

7 May 2021

A single archaeal enzyme can produce a spectacular range of natural and non-natural cardiolipins

Cells of all life forms are surrounded by a membrane that is made of phospholipids. One of these are the cardiolipins, which form a separate class due to their unique structure.

7 May 2021

Bubonic plague had long-term impact on human immune genes, indicates study

Scientists examining the remains of 36 bubonic plague victims from a 16th century mass grave in Germany have found the first evidence that evolutionary adaptive processes, driven by the disease, may have conferred immunity on later generations of people from the region.

7 May 2021

Study may lead to personalized treatments for cystic fibrosis

Some 2,103 mutations have been identified in patients with cystic fibrosis (CF), the most common fatal genetic disease in Canada, and together they pose huge challenges for patients and researchers, including those affiliated with Université de Montreal and its teaching hospital, the Centre hospitalier de l'Université de Montréal (CHUM).

7 May 2021

Israeli study shows real-world efficacy of Pfizer-BioNTech’s COVID-19 vaccine

Researchers have conducted an analysis of nationwide surveillance data from Israel demonstrating the real-world effectiveness of Pfizer-BioNTech’s BNT162b2 vaccine at protecting against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

6 May 2021

Study provides a better understanding of the complex interplay of ncRNAs with gene regulation

Researchers at the University of Eastern Finland have discovered previously unknown non-coding RNAs (ncRNAs) involved in regulating the gene expression of vascular endothelial growth factors (VEGF), the master regulators of angiogenesis.

6 May 2021

Embryo gene editing in IVF can have potential major impacts on humanity

A global conference on human fertility has been warned of huge societal and ethical challenges regulating advances in gene editing in assisted reproduction.

6 May 2021

Black swan DNA could offer insight into how humans respond to bird flu

In a world-first, scientists from The University of Western Australia have assembled the entire DNA of the black swan, which could offer insight into how the bird, and even humans, respond to bird flu and other pandemics in the same family of viruses.

6 May 2021

Researchers study sex-specific gene mutation linked to autism

After reviewing a database of gene mutations in children with autism spectrum disorder (ASD), a team of Medical University of South Carolina (MUSC) researchers decided to study a specific gene mutation that likely caused ASD in a girl.

6 May 2021

Study reveals a new form of muscular dystrophy associated with pathogenic changes in JAG2 gene

In about a quarter of patients with hereditary diseases, the cause of the disease remains unclear even after extensive genetic testing. One reason is that we still do not know enough about the function of many genes. Of the 30,000 known genes, just a little more than 4,000 have been found to be associated with hereditary diseases.

6 May 2021

Monocytes promote viral control during SARS-COV-2 infection

In a paper recently uploaded to the preprint server bioRxiv by Vanderheiden et al. (May 4th, 2021) the contribution of monocytes in promoting protective immunity from SARS-CoV-2 is investigated in a murine model, suggesting that CCR2 plays the role of an inflammation modulator in early infection.

6 May 2021

Nanoscope presents optical gene delivery, OCT-guided electrophysiology platforms at ARVO annual meeting

Nanoscope Technologies LLC, a biotechnology company developing gene therapies for treatment of retinal diseases, is featuring multiple scientific presentations highlighting its groundbreaking research on optical gene delivery for vision restoration and OCT-guided electrophysiology platforms for characterization of retinal degeneration and assessment of efficacy of cell-gene therapy at the 2021 ARVO annual (virtual) meeting, May 1-7.

5 May 2021

Novel pipeline identifies millions of molecular targets in SARS-CoV-2

Researchers in the United States have developed a novel pipeline for high-throughput, automated annotation of the genes, proteins and functional domains in the genome of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

5 May 2021

Researchers show how low-protein diet during pregnancy can cause kidney problems in babies

Besides being underweight, babies born to women whose diet lacked sufficient protein during pregnancy tend to have kidney problems resulting from alterations that occurred while their organs were forming during the embryonic stage of their development.

5 May 2021

New genetic mutation increases risk for atrial fibrillation, heart failure in Black people

A new mutation found in a gene associated with an increased risk of atrial fibrillation poses a significantly increased risk for heart failure in Black people.

5 May 2021

Study suggests GILZ protein as a promising anti-hepatic fibrosis drug target

Scientists from Russia and Italy studied a new axis of the pathway that prevents the development of liver fibrosis. The role of GILZ protein in curbing the disease progression was shown in a study using mice models and confirmed by clinical data.

5 May 2021

Certain parts of the innate immune response can be trained in response to HIV

Immunity often calls to mind the adaptive immune response, made up of antibodies and T cells that learn to fight specific pathogens after infection or vaccination.

5 May 2021

Study identifies novel combination therapy to help patients with advanced lung cancer

A new study by researchers at the UCLA Jonsson Comprehensive Cancer Center has identified a novel combination therapy to potentially help overcome resistance to immunotherapy in people diagnosed with advanced lung cancer.

5 May 2021

Researchers identify new immunotherapy treatment target for acute myeloid leukemia in children

Researchers have identified a gene expressed in children with acute myeloid leukemia (AML) that could serve as a new immunotherapy treatment target, according to a new study published today in Blood Advances, a journal of the American Society of Hematology.

5 May 2021

Gene News and Research

Latest Gene News and Research

Researchers describe the key facet of sexual determination in mammalian models

Molecular clues explain why some neurons are more susceptible than others in Alzheimer’s disease

A single archaeal enzyme can produce a spectacular range of natural and non-natural cardiolipins

Bubonic plague had long-term impact on human immune genes, indicates study

Study may lead to personalized treatments for cystic fibrosis

Israeli study shows real-world efficacy of Pfizer-BioNTech’s COVID-19 vaccine

Study provides a better understanding of the complex interplay of ncRNAs with gene regulation

Embryo gene editing in IVF can have potential major impacts on humanity

Black swan DNA could offer insight into how humans respond to bird flu

Researchers study sex-specific gene mutation linked to autism

Study reveals a new form of muscular dystrophy associated with pathogenic changes in JAG2 gene

Monocytes promote viral control during SARS-COV-2 infection

Nanoscope presents optical gene delivery, OCT-guided electrophysiology platforms at ARVO annual meeting

Novel pipeline identifies millions of molecular targets in SARS-CoV-2

Researchers show how low-protein diet during pregnancy can cause kidney problems in babies

New genetic mutation increases risk for atrial fibrillation, heart failure in Black people

Study suggests GILZ protein as a promising anti-hepatic fibrosis drug target

Certain parts of the innate immune response can be trained in response to HIV

Study identifies novel combination therapy to help patients with advanced lung cancer

Researchers identify new immunotherapy treatment target for acute myeloid leukemia in children

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