Gene News and Research

Latest Gene News and Research

Stem cells that repair broken bones can also generate arthritic bone spurs

The same stem cells that heal broken bones can also generate arthritic bone spurs called osteophytes, according to a new study in the Annals of the Rheumatic Diseases.

12 Oct 2020

Study provides a new depth of resolution to understand single gene disorders

Traditionally, geneticists divide disorders into "simple," where a single gene mutation causes disease, or complex, where mutations in many genes contribute modest amounts. A new study suggests that the truth is somewhere in between.

12 Oct 2020

Dynamic map reveals how cells fight microbes and preserve memory for future infections

Researchers have charted the activity of tens of thousands of genes in mouse immune cells over the course of an infection.

12 Oct 2020

Study elucidates the role of ERβ in growth of skeletal muscle in female mice

Researchers at Kumamoto University, Japan generated mice lacking the estrogen receptor beta (ERβ) gene, both fiber-specific and muscle stem cell-specific, which resulted in abnormalities in the growth and regeneration of skeletal muscle in female mice.

12 Oct 2020

Computational biology algorithm could help optimize culture conditions required for cell therapy

Cellular therapy is a powerful strategy to produce patient-specific, personalised cells to treat many diseases, including heart disease and neurological disorders.

12 Oct 2020

Gene variations that regulate dopamine levels in the brain may influence mobility of elderly, frail adults

Variations in a gene that regulates dopamine levels in the brain may influence the mobility of elderly and frail adults, according to new research from the University of Pittsburgh Graduate School of Public Health.

12 Oct 2020

Researchers identify new mechanism underlying the progression of FAP-associated Desmoid tumor

Volume 11, Issue 26 of Oncotarget reported that in this study the authors studied the differences in mi RNA expression between sporadic and FAP-associated Desmoid tumors using microarray confirmed by quantitative PCR.

12 Oct 2020

Study shows how mutations in VAV1 gene may promote T-cell tumors in experimental mice

Life is an exquisite orchestration of growth and change, with checks and balances that fine-tune complex entwined interactions, both intrinsic and external.

12 Oct 2020

Scientists discern molecular mechanisms underlying plant parasitism, cross-species grafting

Using the model Orobanchaceae parasitic plant Phtheirospermum japonicum, scientists from Nagoya University and other research institutes from Japan have discerned the molecular mechanisms underlying plant parasitism and cross-species grafting, pinpointing enzyme β-1,4-glucanase (GH9B3) as an important contributor to both phenomena.

12 Oct 2020

Researchers identify molecular mechanisms of IFN responses in SARS-CoV-2 infection

As of October 2020, SARS-CoV-2 causes an ongoing pandemic, with more than 35 million reported cases and more than 1 million deaths worldwide. One prominent feature that distinguishes COVID-19 from SARS in terms of immune responses is the poor induction of a type I interferon (IFN) response by SARS-CoV-2 compared to SARS-CoV and influenza A virus.

12 Oct 2020

NIH provides $9.3 million grant to create new Center for Precision Animal Modeling at UAB

A new Center for Precision Animal Modeling, or C-PAM, has been created at the University of Alabama at Birmingham, supported by a five-year, $9.3 million grant from the National Institutes of Health's Office of Research Infrastructure Programs.

9 Oct 2020

Genomic study shows the evolutionary history of banyan trees and their wasp pollinators

The banyan fig tree Ficus microcarpa is famous for its aerial roots, which sprout from branches and eventually reach the soil.

9 Oct 2020

Study reveals how ovaries maintain a female's fertility

Recently published work from Carnegie's Allan Spradling and Wanbao Niu revealed in unprecedented detail the genetic instructions immature egg cells go through step by step as they mature into functionality.

9 Oct 2020

Researchers apply CRISPR technology to eliminate fusion genes present in tumor cells

The CRISPR/Cas9 gene-editing tool is one of the most promising approaches to advancing treatments of genetic diseases - including cancer -, an area of research where progress is constantly being made.

9 Oct 2020

Virginia Tech to build a cyberinfrastructure for wastewater antibiotic-resistant gene monitoring

Antibiotic resistance is a grand challenge of the 21st century. According to the U.S. Centers for Disease Control and Prevention, antibiotic resistance rates are increasing globally, with an estimated 35,000 related deaths per year in the United States in 2019, compared to 23,000 in 2013.

8 Oct 2020

Breakthrough genetic discovery into the cause of severe neurological conditions

Researchers have made a breakthrough genetic discovery into the cause of a spectrum of severe neurological conditions.

8 Oct 2020

Research uncovers a novel way of preventing or treating epilepsy

Epileptic seizures often originate in small, localized areas of the brain where neurons abnormally fire in unison.

8 Oct 2020

Using mRNA therapies or CRISPR gene editing to treat cystic fibrosis

The potential for treating cystic fibrosis (CF) using mRNA therapies or CRISPR gene editing is possible regardless of the causative mutation. CF clinical trials showing that a genotype-agnostic gene therapy for CF is possible are reviewed in the peer-reviewed journal Human Gene Therapy.

8 Oct 2020

Laser irradiation shows promise as a new treatment modality for osteoporosis

Osteoporosis is a disease in which bone loses mass as a result of age or other influences. This weakening is the leading cause of fractures in the elderly, often after trivial injuries, and makes treating these "pathological fractures" a challenge.

8 Oct 2020

Exome sequencing sheds light on genetic causes of nonimmune hydrops fetalis

A new study by University of California researchers shows the promise of high-throughput DNA-sequencing technologies to improve prenatal diagnosis and pregnancy outcomes for women who have experienced an abnormal prenatal ultrasound.

8 Oct 2020

Gene News and Research

Latest Gene News and Research

Stem cells that repair broken bones can also generate arthritic bone spurs

Study provides a new depth of resolution to understand single gene disorders

Dynamic map reveals how cells fight microbes and preserve memory for future infections

Study elucidates the role of ERβ in growth of skeletal muscle in female mice

Computational biology algorithm could help optimize culture conditions required for cell therapy

Gene variations that regulate dopamine levels in the brain may influence mobility of elderly, frail adults

Researchers identify new mechanism underlying the progression of FAP-associated Desmoid tumor

Study shows how mutations in VAV1 gene may promote T-cell tumors in experimental mice

Scientists discern molecular mechanisms underlying plant parasitism, cross-species grafting

Researchers identify molecular mechanisms of IFN responses in SARS-CoV-2 infection

NIH provides $9.3 million grant to create new Center for Precision Animal Modeling at UAB

Genomic study shows the evolutionary history of banyan trees and their wasp pollinators

Study reveals how ovaries maintain a female's fertility

Researchers apply CRISPR technology to eliminate fusion genes present in tumor cells

Virginia Tech to build a cyberinfrastructure for wastewater antibiotic-resistant gene monitoring

Breakthrough genetic discovery into the cause of severe neurological conditions

Research uncovers a novel way of preventing or treating epilepsy

Using mRNA therapies or CRISPR gene editing to treat cystic fibrosis

Laser irradiation shows promise as a new treatment modality for osteoporosis

Exome sequencing sheds light on genetic causes of nonimmune hydrops fetalis

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging