Gene News and Research

Latest Gene News and Research

Three new research teams aim to improve therapies for difficult-to-treat pediatric cancers

While incredible progress has been made in advancing pediatric cancer research, critical unmet needs still exist, especially for more aggressive cancers such as neuroblastomas and Ewing sarcoma.

19 Oct 2020

Cytotoxic NK cells also have immunological memory function

Good news for the human immune system: researchers from MedUni Vienna's Departments of Dermatology and Surgery have managed to ascribe an immunological memory function to a subset of cytotoxic NK cells, which have hitherto been regarded as antigen-non-specific.

19 Oct 2020

Study provides possible explanation for progressive course of multiple sclerosis in mice

People with multiple sclerosis gradually develop increasing functional impairment. Researchers at Karolinska Institutet in Sweden have now found a possible explanation for the progressive course of the disease in mice and how it can be reversed.

16 Oct 2020

Tracing lineage to demonstrate direct astrocyte-to-neuron conversion in mouse brain

Regeneration of functional new neurons to repair injured human brain is a long-term unsolved problem up till today.

16 Oct 2020

Researchers develop new strategy to improve siRNA stability

RNA interference is a gene regulatory mechanism in which the expression of specific genes is downregulated by endogenous microRNAs or by small interfering RNAs (siRNAs).

16 Oct 2020

Gene variants may provide clues to successful treatment of pediatric eosinophilic esophagitis

A group of three gene variants, commonly inherited together, may provide clues to more successful treatment of pediatric eosinophilic esophagitis (EoE), a chronic inflammation of the food pipe often confused with gastroesophageal reflux disease (GERD).

16 Oct 2020

CRISPR-based engineered cell lines can accelerate potential treatment targets for SARS-CoV-2

Synthego, the genome engineering company, has collaborated with The Krogan Lab, a world-renowned scientific research unit at the Quantitative Biosciences Institute (QBI) at the University of California, San Francisco (UCSF), to deliver multiple CRISPR-based engineered cell lines to accelerate the study of potential treatment targets for SARS-CoV-2, the novel coronavirus that causes COVID-19 disease.

16 Oct 2020

Patients with soft-tissue cancer show rapid and complete response to novel combination of immunotherapy

A patient with end-stage and rapidly progressing soft-tissue cancer whose tumor did not respond to standard treatment, had a "rapid and complete response" to a novel combination of immunotherapy, according to new research published by a team of scientists from John Theurer Cancer Center at Hackensack University Medical Center and the Georgetown Lombardi Comprehensive Cancer Center, both of whom are part of the Georgetown Lombardi Comprehensive Cancer Center Consortium.

16 Oct 2020

Rapid development of functionally diverse SARS-COV-2 mouse monoclonal antibodies

Now, a recent study published on the preprint server bioRxiv in October 2020 reports the development of a rapid process for generating high-affinity mouse mAbs, and their functional attributes.

16 Oct 2020

Exposure to ancient parasites may be linked to humans’ response to coronavirus

Why are some people more resilient to viruses than others? The answer has eluded scientists for centuries and, in the age of COVID-19, has come to represent one of the holy grails of biomedical research.

16 Oct 2020

Synthetic signals could help control tissue regeneration, guide cellular therapies

For a tiny embryo to develop into an adult organism, its cells must develop in precise patterns and interact with their neighbors in carefully orchestrated ways.

16 Oct 2020

Early trauma leads to changes in blood metabolites, study finds

A study by the Brain Research Institute at UZH reveals that early trauma leads to changes in blood metabolites - similarly in mice and humans.

15 Oct 2020

NIH grants 4D Nucleome award to support research by Gladstone scientists

The National Institutes of Health has granted a 4D Nucleome award to support research by a group of scientists at Gladstone Institutes led by Benoit Bruneau, PhD, and Katie Pollard, PhD.

15 Oct 2020

UTHSC professor receives $2.2 million for research into arterial stiffness and hypertension

In humans, large arteries lose elasticity and thicken with age and other pathological conditions, leading to arteriosclerosis and high blood pressure.

15 Oct 2020

Moffitt study uncovers how specific molecules promote cancer progression

The development of cancer is a highly complicated process, involving multiple genes and signaling pathways that become upregulated or downregulated throughout different stages of tumor growth and spread.

15 Oct 2020

UCI-led researchers receive $3 million NIH grant for 4D Nucleome project

The National Institutes of Health has awarded a team of researchers, led by the University of California, Irvine's Xiangmin Xu, PhD, a five-year, $3 million grant for a project titled, "Single-Cell Analysis of Aging-Associated 4D Nucleome in the Human Hippocampus."

15 Oct 2020

Small molecule restores normal heart development in animal model with rare genetic disorder

A research team at the Greenwood Genetic Center has successfully used small molecules to restore normal heart and valve development in an animal model for Mucolipidosis II (ML II), a rare genetic disorder. Progressive heart disease is commonly associated with ML II.

15 Oct 2020

Small RNA molecule controls major pathogenicity factors of H. pylori

More than half of the world's population carries the bacterium Helicobacter pylori in their stomach mucosa. It often causes no problems throughout life, but sometimes it can cause inflammation, and in some cases, it can even lead to the development of stomach cancer.

15 Oct 2020

Genomic analysis of neuroblastoma sheds light on childhood solid tumors

Researchers have used insight from a comprehensive genomic analysis of neuroblastoma to learn about the process driving one of the most common childhood solid tumors. The findings revealed possible approaches for developing precision medicines to improve patient outcomes. St. Jude Children's Research Hospital scientists led the study, which appears today in the journal Nature Communications.

15 Oct 2020

GIV protein involved in the immune system could form basis for novel therapeutics

The immune response to infections is a delicate balance. We need just enough action to clear away the offending bacteria or viruses, but not so much that our own bodies suffer collateral damage.

15 Oct 2020

Gene News and Research

Latest Gene News and Research

Three new research teams aim to improve therapies for difficult-to-treat pediatric cancers

Cytotoxic NK cells also have immunological memory function

Study provides possible explanation for progressive course of multiple sclerosis in mice

Tracing lineage to demonstrate direct astrocyte-to-neuron conversion in mouse brain

Researchers develop new strategy to improve siRNA stability

Gene variants may provide clues to successful treatment of pediatric eosinophilic esophagitis

CRISPR-based engineered cell lines can accelerate potential treatment targets for SARS-CoV-2

Patients with soft-tissue cancer show rapid and complete response to novel combination of immunotherapy

Rapid development of functionally diverse SARS-COV-2 mouse monoclonal antibodies

Exposure to ancient parasites may be linked to humans’ response to coronavirus

Synthetic signals could help control tissue regeneration, guide cellular therapies

Early trauma leads to changes in blood metabolites, study finds

NIH grants 4D Nucleome award to support research by Gladstone scientists

UTHSC professor receives $2.2 million for research into arterial stiffness and hypertension

Moffitt study uncovers how specific molecules promote cancer progression

UCI-led researchers receive $3 million NIH grant for 4D Nucleome project

Small molecule restores normal heart development in animal model with rare genetic disorder

Small RNA molecule controls major pathogenicity factors of H. pylori

Genomic analysis of neuroblastoma sheds light on childhood solid tumors

GIV protein involved in the immune system could form basis for novel therapeutics

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging