Gene News and Research

Latest Gene News and Research

Transcriptomics identifies possible COVID-19 therapies

By using a diverse set of transcriptomic SARS-CoV-2 signatures, US researchers put to use their previously developed drug repositioning pipeline to pinpoint potential drug candidates for the treatment of coronavirus disease (COVID-19). The study is currently available on bioRxiv preprint server.

26 Oct 2020

Research uncovers SARS-CoV-2 viral traits critical for the virus in human airways

A new study published on the preprint server bioRxiv* in October 2020 reports the discovery of important viral genomic features that are crucial to its replication in the human airway cells, and its enhancing mutations which increase the rate of replication and determine its target cells.

26 Oct 2020

New inhibitor of SARS-CoV-2 RNA translation

As the search for effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibitors continues, a recent study by Yale University School of Medicine researchers published on the preprint server bioRxiv in October 2020 reports the inhibitory effect of the drug merofloxacin on frameshifting during SARS-CoV-2 replication.

26 Oct 2020

Molecular processes in kidney cells may increase diabetics' vulnerability to COVID-19 infection

People with diabetes -- especially the 20 to 40 percent with diabetic kidney disease -- are among the most at risk for serious complications and death from COVID-19.

23 Oct 2020

Researchers find a new therapeutic approach to combat leukemia

Leukemia frequently originates from the so-called leukemic stem cell, which resides in a tumor promoting and protecting niche within the bone marrow. Scientists from the Max Planck Institute of Biochemistry in Martinsried, Germany, have found a new way to make these cells vulnerable by specifically dislodging these cells from their niches.

23 Oct 2020

Researchers develop lab-grown lung model to study SARS-CoV-2 infection

A team of Duke University researchers has developed a lab-grown living lung model that mimics the tiny air sacs of the lungs where coronavirus infection and serious lung damage take place.

23 Oct 2020

Researchers use viral signatures to reveal transmission patterns of SARS-CoV-2

The coronavirus, responsible for the COVID-19 pandemic, has one official name--SARS-CoV-2. But according to virologists, mutations lead to hundreds of genetically-distinct versions of the virus.

23 Oct 2020

$109 million NIH grant awarded to expand Alzheimer's disease and Down syndrome research

The Alzheimer's Biomarkers Consortium - Down Syndrome, a multi-institution research team, co-led by members from the University of California, Irvine, has been awarded an unprecedented five-year, $109 million grant by the National Institutes of Health, to expand research on the biomarkers of Alzheimer's disease in adults with Down syndrome.

22 Oct 2020

Distinct DNA methylation signature found in the cord blood of newborns diagnosed with ASD

A new study led by UC Davis MIND Institute researchers found a distinct DNA methylation signature in the cord blood of newborns who were eventually diagnosed with autism spectrum disorder (ASD).

22 Oct 2020

DNA vaccine-induced antibodies neutralize SARS-CoV-2

The coronavirus disease (COVID-19) is far from over as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to ravage across the globe. With the vast spread of the virus, many countries who reported flattening the curve over the past months have reported clusters of new cases and second waves of the outbreak.

22 Oct 2020

Virginia Tech doctoral candidate wins NIH award to fuse immunology and neuroscience research

Gabriela Carrillo didn't always aspire to be a neuroscientist. It wasn't until she was providing in-home behavioral analysis therapy for children with autism that she was drawn to the lab.

22 Oct 2020

Study shows how genetic predisposition contributes to the development of multiple sclerosis

About half of the people with multiple sclerosis have the HLA-DR15 gene variant. A study led by the University of Zurich has now shown how this genetic predisposition contributes to the development of the autoimmune disease multiple sclerosis in combination with environmental factors.

22 Oct 2020

Santen joins forces with ophthalmologists in the fight against antibiotic resistance

Santen is delighted to announce the launch of the Re-SOLVE Antibiotic Resistance, which aims to lead the way in the fight against antibiotic resistance.

22 Oct 2020

Tumor DNA in spinal fluid can help track children with aggressive brain tumors

For many cancers, doctors are increasingly looking to the DNA that solid tumors shed into the blood stream to help with diagnosis and monitoring. But brain cancer has been a different story thanks to the natural blockade created by the blood-brain barrier.

22 Oct 2020

Study shows how genome sequencing can track mutations in SARS-CoV-2 virus

A study published in Cell Reports shows how next generation genetic sequencing can track mutations in the SARS-CoV-2 virus, which can in effect help with transmission tracing, diagnostic testing accuracy and vaccine effectiveness.

22 Oct 2020

Newly developed light-sensing protein restores vision in blind mice

A newly developed light-sensing protein called the MCO1 opsin restores vision in blind mice when attached to retina bipolar cells using gene therapy.

22 Oct 2020

Congress should clarify limits of gene-editing technologies, says law professor

Genome editing of human embryos represents one of the most contentious potential scientific applications today. But what if geneticists could sidestep the controversy by editing sperm and eggs instead?

22 Oct 2020

Study may help develop effective therapeutic strategies against COVID-19

People have different susceptibilities to SARS-CoV-2, the virus behind the COVID-19 pandemic, and develop varying degrees of fever, fatigue, and breathing problems -- common symptoms of the illness. What might explain this variation?

22 Oct 2020

Mayo clinic researchers develop a potential test for Machado-Joseph disease

Mayo Clinic researchers, along with national and global collaborators, have developed a potential test for Machado-Joseph disease, or spinocerebellar ataxia type 3 (SCA3) ? a disease that has no cure.

22 Oct 2020

Researchers assess molecular basis of SARS-CoV-2 severity and poor outcomes in lung disease

A recent study published on the preprint server bioRxiv in October 2020 shows that in patients with chronic lung disease, the pattern of gene expression in the different types of cell changes such that the lung epithelium is prepared to tackle SARS-CoV-2 infection. Also, the altered gene programs have an impact on the immune response.

22 Oct 2020

Gene News and Research

Latest Gene News and Research

Transcriptomics identifies possible COVID-19 therapies

Research uncovers SARS-CoV-2 viral traits critical for the virus in human airways

New inhibitor of SARS-CoV-2 RNA translation

Molecular processes in kidney cells may increase diabetics' vulnerability to COVID-19 infection

Researchers find a new therapeutic approach to combat leukemia

Researchers develop lab-grown lung model to study SARS-CoV-2 infection

Researchers use viral signatures to reveal transmission patterns of SARS-CoV-2

$109 million NIH grant awarded to expand Alzheimer's disease and Down syndrome research

Distinct DNA methylation signature found in the cord blood of newborns diagnosed with ASD

DNA vaccine-induced antibodies neutralize SARS-CoV-2

Virginia Tech doctoral candidate wins NIH award to fuse immunology and neuroscience research

Study shows how genetic predisposition contributes to the development of multiple sclerosis

Santen joins forces with ophthalmologists in the fight against antibiotic resistance

Tumor DNA in spinal fluid can help track children with aggressive brain tumors

Study shows how genome sequencing can track mutations in SARS-CoV-2 virus

Newly developed light-sensing protein restores vision in blind mice

Congress should clarify limits of gene-editing technologies, says law professor

Study may help develop effective therapeutic strategies against COVID-19

Mayo clinic researchers develop a potential test for Machado-Joseph disease

Researchers assess molecular basis of SARS-CoV-2 severity and poor outcomes in lung disease

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