Gene News and Research

Latest Gene News and Research

Study uncovers sex-specific differences in neural mechanisms for glucose regulation

Researchers at Tufts University School of Medicine and Tufts Graduate School of Biomedical Sciences have discovered neural mechanisms in mice specific to females that can shift estrogen from playing a protective role in glucose metabolism to one that is disruptive.

6 Aug 2020

Researchers develop a deep learning-based algorithm for predicting sites of DNA methylation

A team of researchers from New Jersey Institute of Technology and Children's Hospital of Philadelphia have developed an algorithm through machine learning that helps predict sites of DNA methylation - a process that can change the activity of DNA without changing its overall structure - and could identify disease-causing mechanisms that would otherwise be missed by conventional screening methods.

6 Aug 2020

Powerful treatment for IPF stops dangerous scar formation in mouse lungs

A pre-clinical study led by scientists at Cincinnati Children's demonstrates that in mice the drug barasertib reverses the activation of fibroblasts that cause dangerous scar tissue to build up in the lungs of people with idiopathic pulmonary fibrosis (IPF).

6 Aug 2020

Study finds evidence of gut dysbiosis in people with Huntington's disease

A world first clinical study of the gut microbiome in people with Huntington's disease (HD) has found that it is not just a disease of the brain, but also of the body.

6 Aug 2020

WVU RNI expands pioneering treatment for Alzheimer’s to open the blood-brain barrier

A hospital nurse for 33 years, Nanette Miller would call her husband Frank at the end of each shift to let him know she was coming home. On Dec. 7, 2018, the phone call came with a somber declaration: "I can't do this anymore."

6 Aug 2020

Tasmanian devil research provides new insights for treating human cancers in future

A rare, transmissible tumor has brought the iconic Tasmanian devil to the brink of extinction, but new research by scientists at Washington State University and the Fred Hutchinson Cancer Research Center in Seattle indicates hope for the animals' survival and possibly new treatment for human cancers.

6 Aug 2020

Specific gene impairment may also protect people with Down syndrome

Scientists from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago discovered that a set of genes with decreased expression in individuals with Down syndrome may lead to clinical abnormalities in this population, such as poor muscle development and heart valve problems.

6 Aug 2020

Gene could predict treatment response in certain breast cancer patients

Scientists have identified a gene which if present in certain breast cancer patients indicates how they will respond to specific therapies.

6 Aug 2020

Unique molecular mechanics can pave way for potential treatments for infections

Unique molecular mechanics allowing parasites to thrive in the guts of one billion people open the door to new treatments that are safe for the host.

6 Aug 2020

Researchers shed new light on epigenetic changes associated with ADNP syndrome

A study led by the Seaver Autism Center for Research and Treatment at Mount Sinai found that two different blood epigenetic signatures associated with ADNP syndrome (also known as Helsmoortel-Van Der Aa syndrome) have only a modest correlation with clinical manifestations of the syndrome. The study results were published online August 5 in the American Journal of Human Genetics.

6 Aug 2020

Scientists create new mouse model of permanent neonatal diabetes

Diabetes seldom occurs in newborns--a condition known as neonatal diabetes. But when it does, it's mostly due to a mutation in a single gene such as the KCNJ11 or insulin (INS).

6 Aug 2020

Carefully engineered spike protein can help develop COVID-19 vaccine

The experimental vaccine against SARS-CoV-2 that was the first to enter human trials in the United States has been shown to elicit neutralizing antibodies and a helpful T-cell response with the aid of a carefully engineered spike protein that mimics the infection-spreading part of the virus.

6 Aug 2020

Researchers investigate why irregular heartbeats occur after stem cell transplantation

Stem cells are heavily studied around the world with the hope to revive damaged body parts unable to regenerate itself. Injured heart muscles are one of these areas which remain impaired in adults who have experienced heart attacks.

5 Aug 2020

3D organoid model helps better understand how tumor grows in natural microenvironment

Scientists at the Wake Forest Institute for Regenerative Medicine (WFIRM) have biofabricated human colorectal cancer miniature organs, called organoids, to better understand how a tumor grows in its natural microenvironment and its response to therapies.

5 Aug 2020

Gene News and Research

Latest Gene News and Research

Study uncovers sex-specific differences in neural mechanisms for glucose regulation

Researchers develop a deep learning-based algorithm for predicting sites of DNA methylation

Powerful treatment for IPF stops dangerous scar formation in mouse lungs

Study finds evidence of gut dysbiosis in people with Huntington's disease

WVU RNI expands pioneering treatment for Alzheimer’s to open the blood-brain barrier

Tasmanian devil research provides new insights for treating human cancers in future

Specific gene impairment may also protect people with Down syndrome

Gene could predict treatment response in certain breast cancer patients

Unique molecular mechanics can pave way for potential treatments for infections

Researchers shed new light on epigenetic changes associated with ADNP syndrome

Scientists create new mouse model of permanent neonatal diabetes

Carefully engineered spike protein can help develop COVID-19 vaccine

Researchers investigate why irregular heartbeats occur after stem cell transplantation

3D organoid model helps better understand how tumor grows in natural microenvironment

A SARS-CoV-2 assay using plant proteins

Discovery of enzyme could provide new route for treating Huntington's disease

New research project receives federal funding to expand treatment options for sickle cell patients

Study provides comprehensive update on ACE2 enzyme with key role in SARS-CoV-2 infection

Study shows the strategies tumor cells use to evade immune defense

Horizon Discovery introduces single cell RNAseq-linked CRISPR screening service

eBook: Using iPSCs models for human disease research and drug discovery eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging